Alessandro Sclafani

[Isabel Martín Fuentes @Isamarffu]

🚨New publication🚨
“Gait Variability Is Associated With Gray Matter Volumes Implicated in Cognitive Function”
A cross-sectional analysis from the @aguedaproject, now in Innovation in Aging
https://t.co/QR6iG6fKYy
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[Alessandro Sclafani @Ale_sclafani]

🧠6/6
🙏 A huge thank you to the @profithugr team and @aguedaproject for all the work behind this publication. I’m truly grateful for your support and availability throughout the process!

[Alessandro Sclafani @Ale_sclafani]

🧠4/6
📢Practical implications
Shift time toward MVPA. Replacing sedentary behavior, light PA, or excess sleep time with MVPA could be a promising strategy to support region-specific brain health in cognitively unimpaired older men

[Alessandro Sclafani @Ale_sclafani]

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💬Given the exploratory nature of this study, these results require further validation in larger samples and longitudinal designs

#BrainHealth #HealthyAging #PhysicalActivity #Alzheimers #MVPA #AmyloidBeta #Neuroscience #Research #CoDA

[Alessandro Sclafani @Ale_sclafani]

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📉Another interesting finding
We found a dose–response pattern according to the PA guidelines. Particularly, ‘very active’ males (more than 300 min/week of MVPA) showed lower hippocampal Aβ levels than ‘inactive’ males (less than 150 min/week of MVPA)

[Alessandro Sclafani @Ale_sclafani]

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📉Key findings
Movement behaviors were not associated with global amyloid levels or executive function. However, higher moderate-to-vigorous physical activity (MVPA) may be protective against hippocampal amyloid levels in older males

[Alessandro Sclafani @Ale_sclafani]

🚨‍‍New publication by @aguedaproject !🚨
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“Association of 24h-movement behaviors with cerebral and hippocampal amyloid beta (Aβ) levels and executive function in cognitively normal older adults: a compositional data analysis from the AGUEDA trial”
https://t.co/bDy459rr6q

[Alessandro Sclafani @Ale_sclafani]

Thanks to @bhecongress for the opportunity to share my preliminary results on the association between hippocampal beta amyloid levels and movements behaviors. It was a great pleasure partecipate in this amazing congress. See you in the next one! #bhe24 #brain #health #research

[Patricio Solis Urra @Patricio__Solis]

Exciting news! Our resistance exercise-based RCT (AGUEDA) protocol paper (https://t.co/2kBfeFcdlA), focusing on brain health in cognitively older adults, has been published in Frontiers in Human Neuroscience this week. Here are some key highlights: