Ha An

Single-cell Specialist | Sequencing, functional screening, 3D culture & more

[Anh Nguyen @anh_nhn_]

🔥Time for my favorite bacterial lipid: 🦠Hopanoids!🦠 Our lab new preprint shows that a lipid's double bond position can affect hopanoid-lipid interaction, and consequently, net membrane properties!
Check out here for more:

[Massachusetts Institute of Technology (MIT) @MIT]

A new method for purifying protein drugs, such as antibodies or insulin, is much less expensive than conventional approaches. “The goal is to reduce the cost so that this kind of drug manufacturing becomes affordable,” says Kripa Varanasi. https://t.co/XAppJsafBL

[Ha An @Andiscovery]

Happy to be back to a big in-person event like #ASHG2022. It feels familiar yet so different after the last 2 years. Here I am again, ready to learn and to make some great connections 😊#DolomiteBio

[RNA-Seq Blog @RNASeqBlog]

The Big Data Portal enables scientists worldwide to connect to the @bioturing server and analyze in real time the largest collections of #singlecell datasets. https://t.co/cmTBcxVh6W

[Holger Heyn @hoheyn]

IT IS OUT @NatureBiotech.
Super-sensitive #singlecell RNAseq with Smart-seq3. Full-length transcriptome and very deep phenptyping information. We all shouldn't use anything else from now on. Congrats @sandberglab!
https://t.co/934rk6e5fJ

[Jeremy Hirota @jeremyhirota]

Our preprint profiling host molecules related to SARS-CoV-2 infection in human lung tissue and epithelium - at gene and protein level - is now out.
@DrLindskog @ACDoxey @IPFdoc @sci_questions @Millerlab_atMac @MossmanLab @PollutionLab @McMasterU

https://t.co/EVkB6lZ1vp

[Teichlab @teichlab]

You can now check our COVID-19 Cell Atlas online! https://t.co/RpmEJ4tEfL Great team effort to unravel the cell-specific expression of ACE2 and TMPRSS2 across human tissues @sangerinstitute @humancellatlas

[Shalek Lab @shaleklab]

1/7
In light of the spread of SARS-CoV-2, we are sharing published and unpublished scRNA-seq datasets across both health and disease that harbor cells expressing ACE2 and TMPRSS2, which are critical for SARS-CoV-2 entry into host cells.

[BioTuring @bioturing]

#scRNAseq revealed a progressive diverge in transcriptional profile of CAR-T cells in the blood from that of the infusion product (kudos to @AlyssaSheih, @ValentinVoillet & colleagues at @fredhutch)
The dataset is now indexed in BBrowser: https://t.co/l93fnuh9QP

[Holger Heyn @hoheyn]

Bechmarking #scRNAseq vs #snRNAseq in lung tissue.

1. Same number of genes and molecules when including intronic reads.
2. Less mitochondrial and housekeeping genes in snRNA.
3. Much more epithelial cells snRNA.
4. Much less immune cells in snRNA.
https://t.co/3szq8KgdpB

[Ha An @Andiscovery]

CITE-Seq data analysis/ 10X Genomics Feature Barcoding data analysis with BioTuring Browser
https://t.co/OtpEjSHoWw

[Ken Osaki @ken_osaki]

The landscape of lung bronchoalveolar immune cells in COVID-19 revealed by single-cell RNA sequencing | medRxiv https://t.co/44xt1uzW3F

[Waggoner Lab @LabWaggoner]

Clonotypic expansion of effector-like T cells not only in tumour tissue but also in normal adjacent tissues and peripheral blood associates with clinical response to cancer immunotherapy https://t.co/wGQQNu2WK6

[Xiaole Shirley Liu @XShirleyLiu]

A Herculean effort from Sarah Teichmann lab to profile 250K scRNA-seq (and scTCR-seq) of human thymi in human life stages. Great resource to learn T cell maturation and development. https://t.co/5DpvpKfaY8

[Ha An @Andiscovery]

@AlbertVilella Wow, your worksheet is very informative. Thank you!

[Cecilia Domínguez Conde @CDominguezConde]

Our work on T-cell lineage commitment and TCR recombination in the native thymic microenvironment across human lifespan is online! Fantastic team led by @park_jongeun, Sarah Teichmann, @Muzz_Haniffa and @taghon_t
https://t.co/2ni2H5lgv4

[Fabian Theis @fabian_theis]

We're excited to release a #scanpy update for the analysis and visualization of #spatialTranscriptomics data, focussing on @10xGenomics Visium and MERFISH, thx @g_palla1. Tutorial at https://t.co/zDj2dWkHzp
Support for different data types and integration with #scRNAseq soon!

[BioTuring @bioturing]

Multiple gene query will also be available in the upcoming version of BioTuring #Singlecell Browser, along with the #CITEseq plugin. Stay tuned!

Explore BioTuring Browser: https://t.co/l93fnuh9QP

#scRNAseq

[Linghua Wang, MD, PhD @IamLinghua]

A very useful review! CD8 + T cell states in human cancer: insights from single-cell analysis | Nature Reviews Cancer https://t.co/hNJqQ326Vm

[Ha An @Andiscovery]

Hi Turkey, this is the last chance for you to use BioTuring Single-cell Browser!!!