ANE International

We aim to raise awareness, provide information & support families with #AcuteNecrotizingEncephalopathy ANE is typically triggered by #Influenza & other viruses.

[ANE International @aneinternationa]

For information on #acutenecrotizingencephalopathy or to contact us at ANE International, please refer to our website. https://t.co/4vrNJgCfh6

[ShorterLab @ShorterLab]

RanBP2-dependent SUMOylation of G3BP2 inhibits formation, and promotes disassembly, of stress granules | Molecular Biology of the Cell https://t.co/7p6zc49KSY

[Neurochecklists @neurochecklists]

This is acute necrotizing encephalopathy https://t.co/jKLHdeODG5

[Pediatric Pandemic Network @pedspandemic]

PPN has updated its Influenza-Associated Encephalopathy or Encephalitis (IAE) and Acute Necrotizing Encephalopathy (ANE) resource to help guide patient care. Update includes information on case reporting, clinical characteristics of ANE, and more: https://t.co/erd93nHUY2

[Casanova Lab @casanova_lab]

Brilliant work !
Acute necrotizing encephalopathy associated with COVID-19 in a pediatric patient and a systematic review https://t.co/MDnO9a0akk

[ANE International @aneinternationa]

@cboyca @grok @Saraih33 @BGatesIsaPyscho 109 cases of influenza encephalopathy. 26 cases of ANE (US only).
ANE is not the only type of encephalopathy caused by influenza, but it is the most devastating. Influenza is not the only virus to cause ANE.

[ANE International @aneinternationa]

@ZdenekVrozina Thanks so much for helping to raise awareness of ANE. 👏👏

[ANE International @aneinternationa]

#ANEawareness #acutenecrotizingencephalopathy
#covid #influenza #braininjury

[Zdenek Vrozina @ZdenekVrozina]

The worst form - acute necrotizing encephalopathy (ANE) - inflammatory and hemorrhagic destruction of deep brain structures.
Children with ANE had 44× higher odds of death or severe disability.
ANE isn’t a mild complication - it’s a neuroinflammatory catastrophe.

[Ronald M. Chavin @rmchavin]

Běijīng, Zhōngguó
*By Day 28, acute necrotizing encephalopathy had killed 45.9% of our kids
*Among severe kids with ANE-SS ≥5, 65.7% died
*Death rates were 38.9% (2022), 36.8% (2023), but only 16.7% (2024)
*We could afford Actemra only for our severe kids
https://t.co/DkZPQmaa5C

[sikandar adwani @SikandarAdwani]

15-year-old boy

4 days of fever → seizures → unconscious

CT scan: bilateral thalamic hypodensities.

Not your routine viral encephalitis.

This is where you must think of Acute Necrotizing Encephalopathy (ANE) — a para-infectious cytokine storm that needs early steroids & immunomodulation.

🧠 Recognize early. Act fast. Outcomes depend on it.
#NeuroTwitter #ANE #Encephalopathy #NeurocriticalCare

[I Vaccinate @IVaccinateMI]

"Acute necrotizing encephalopathy" is a rare flu complication in kids, causing brain swelling and immune reactions.

This serves as a harsh reminder of the importance of the flu vaccine, as most of the affected kids had not received it. Read more here: https://t.co/P6YuTrgH71

[Vera Ghali, MD @veraghali]

Influenza-associated acute necrotizing encephalopathy (IA-ANE), is a rare and severe neurologic complication, that causes high morbidity and mortality that presents with encephalitis, fever, seizures, thrombocytopenia, elevated liver enzymes, and elevated protein in the cerebrospinal fluid (CSF), and requires prompt clinical assessment, intensive management and treatment, and prevention.

[Ingo Helbig @IngoHelbig]

Influenza and acute necrotizing encephalopathy – the genetic dimension | Beyond the Ion Channel

...we just published our blog post on Acute Necrotizing Encephalopathy (ANE) and RANBP2 from the recent study in JAMA.

https://t.co/dk8KMZLxc5

[ANE International @aneinternationa]

@tunfairuz We too were very saddened to hear this. #ANEawareness 🥹

[World Federation of Neurology (WFN) @wfneurology]

WFN highlights the latest Neuroinfectious Disease Update [August '25], covering critical developments in influenza-associated encephalopathy (IAE) and acute necrotizing encephalopathy (ANE), H5N1-related encephalitis, and the recent Nipah virus outbreak in Kerala, India. The report emphasizes the importance of early recognition and research on these severe neurologic complications to strengthen global brain health.

Read more here 👉 https://t.co/lQ7k5yO7tU

[ANE International @aneinternationa]

@osalepsy #ANEawareness 👏👏👏

[ANE International @aneinternationa]

@VSLanziotti @NEJM @yoncabulutmd @SapnaKmd @drarunbansal @danicds72 @DrKanaris @LaCampo4 @PedsICU_tweets @PedsICU_JC @Luis_Nando_Carv Thank you for sharing. Awareness is greatly needed. Too many families in our community are initially turned away, "it's just the flu". 🥹 #ANEawareness

[ANE International @aneinternationa]

#ANEawareness
#AcuteNecrotizingEncephalopathy
#influenza
#virus #acquiredbraininjury 🦠🤒⚡️🧠

[Stanford Children's @StanfordChild]

Stanford Medicine researchers hope to raise awareness about a condition called influenza-associated acute necrotizing encephalopathy, to inform parents and physicians about its prevention and treatment. https://t.co/WGYoHAaTc7

[ANE International @aneinternationa]

@StanfordChild Great work, thank you!👏👏

[ANE International @aneinternationa]

⚡️ANE can strike without warning—in anyone, at any age.
Follow the link in our bio for the full story.

👨‍👩‍👧‍👧Together, we can raise awareness.
👨‍👩‍👦‍👦Together, we can save lives. #influenza #ANEawareness
#AcuteNecrotizingEncephalopathy

[ANE International @aneinternationa]

@pash22 @erikaedwardsnbc Thank you for sharing and raising awareness. 😊