‼️ Landmark #lungcancer research published today in Cell
Scientists at the Francis Crick Institute and UCL have discovered a 14-protein blood signature that predicts lung cancer more than 5 years before diagnosis, works in never-smokers, and could identify who benefits from prevention treatment.
People with high levels of these proteins were the ones who actually benefited from a drug to damp that inflammation down, cutting their lung cancer risk nearly in half.
This could finally give us something lung cancer has never had: a way to prevent it in the people most at risk.
https://t.co/SaZwBHnxvZ
#LCSM
The most important paper of #ASCO26 just dropped in Nature Med! Or any other @asco or @myESMO meetings to be honest. When you hear someone present “the toxicities were acceptable”, please respond “downplaying toxicities is not acceptable”. Thank you @NatureMedicine for publishing this piece.
https://t.co/ydAfoTWVJ0
We have 34 faculty, trainees, & staff attending and presenting at the 13th Annual Southeastern Immunology Symposium in Asheville, including Adil Ijaz, PhD; Nicholas Gascoigne, PhD; and Marco Orecchioni, PhD, (@MarcoOrecchioni) each with oral presentations.
#SIS2026#immunology
A new Science #Immunology Review delves into the transcriptional and #epigenetic regulatory mechanisms that shape #macrophage identity and function in health and disease. https://t.co/MYOZv9Edxy
A couple weeks ago, members of IMMCG traveled to Bellevue, Washington, for ATVB's annual Vascular Discover 2026 Scientific Sessions. Klaus Ley, MD, presented, Ravi Komaravolu, PhD, (@angiogen) presented his poster, and our group was featured in the @American_Heart email!
Excited to share our latest paper, out today @CellCellPress. We found that large pieces of the human genome can transfer between cells upon direct contact, endowing recipient cells with heritable phenotypic changes. (1/7)
https://t.co/SbshGhofN0
Early morning Early Career Training Session at #VascularDiscovery26
All-star panel of @ATVBCouncil faculty sharing their advice on cultivating leadership skills, time management, balance, mentorship/sponsorship & more
🔑 Leadership is hard work, specifically budget time for it
Listening to Peter Libby speak at #VascularDiscovery26 about atherosclerosis is always a masterclass in cardiovascular biology.
Some of the related recent papers:
https://t.co/MnQo8pdObg
https://t.co/0H9wQhQRK7
@AHAScience
I am happy to share our protocol paper for wildDISCO technology, a platform for whole-body immunolabeling, clearing and 3D imaging of intact mice at cellular resolution using standard IgG antibodies. https://t.co/f4R8DN0MqZ
This work presents technical details for wildDISCO (Mai&Luo...Ertürk, Nature Biotechnology, 2023, https://t.co/pL6VgT9nF0. The protocol enables deep antibody penetration across the entire body, including challenging regions such as bone marrow, spinal cord and deep organ tissues.
With this approach, we can now map neuronal, vascular, lymphatic and immune systems across the whole organism and study disease processes, cancer metastasis, microbiome interactions and systemic biology in unprecedented detail. The workflow also integrates light-sheet imaging, virtual reality visualization and online atlas generation.
Work led by @jieluo692, @HongchengM . We hope this protocol helps many labs worldwide explore biology at true organism-wide scale.
#DISCO #Clearing #NatureProtocols #SpatialBiology #Imaging #TissueClearing #LightSheetMicroscopy #SystemsBiology #AI #Neuroscience #CancerResearch #wildDISCO
Yesterday, I was giving an intro talk to our dept's new PhD students. Technical things aside, my number 1 suggestion has remained the same over the years: Treat your PhD like a job.
- Avoid 1.5h lunch and three tea breaks.
- Avoid gossiping and loitering at work.
- Lab at 9 am and leave at 6 pm. Being productive till 11 pm in the lab is a lie people till themselves when their day starts at 1 PM.
Everything worth doing can be done with high intensity focus during work hours. And having fun in life is the secret to being productive in a marathon.
Currently my favorite video from the lab...
Mapping of blood vessels and nerves in whole embryos of rhesus macaque.
They form scale-free fractals of dimensions 3 and 2, independently of development stage.
More here: https://t.co/LqZrO7Wnfp