Ångus Hodder

🩸💉🍕🧛🏼‍♂️

[Ångus Hodder @AngusHodder]

https://t.co/Jza5wTR7jl Thrilled paper on routine WGS for children with cancer out today in @NatureMedicine , alongside wider stories https://t.co/dZV8CbBSBL… WGS can provide varied benefits beyond extensive molecular testing
❓Should WGS be SOC for all children with cancer?

[Jack Bartram @DrJackBartram]

Please help this very worthwhile charity @ItsNeverYou22 to get this law back on the table. Support the Parents of Sick Children - Support Hugh's Law https://t.co/zf2y5s9qko via @UKChange

[Jack Bartram @DrJackBartram]

Thank you to all the patients and families involved in this pivotal study which proves the real time, real world evidence for the benefit of whole genome sequence in childhood cancer.

[Great Ormond Street Hospital for Children @GreatOrmondSt]

Heard of whole genome sequencing? Thanks to a national initiative, it's available to all children diagnosed with cancer in England.

Our latest study shows that it can guide on treatment plans for children and reduce the number of tests they need.
https://t.co/IloVFos5uL

[Sky News @SkyNews]

'Genome sequencing gives information about the genome that may be shared with other family members.'

@AngusHodder discusses the child cancer breakthrough research that can help doctors know 'if they need to monitor children and families'

#SJUK https://t.co/immDwEwbK2

📺Sky 501

[Ångus Hodder @AngusHodder]

@SkyNews Anyone interested in the research can see the full paper at https://t.co/Jza5wTRF8T full paper here in @NatureMedicine @DrJackBartram @sangerinstitute @GreatOrmondSt

[Richard Scott @Rich_Genomics]

New research via @NHSgms showing WGS can improve the care of children with cancer.

A great example of using innovative technology to inform individualised care, and of what we can achieve together for patients with WGS as a part of public healthcare

https://t.co/46W5oa70zt

[Oxford-Harrington Rare Disease Centre @OHRareDisease]

A powerful example in @NatureMedicine of how whole genome sequencing can improve clinical care in paediatric oncology and inform individualised medicine for children with cancer @AngusHodder @SarahLeiter @DrJackBartram @AditiVedi and teams @CRUKCamPaeds @NHSgms

[ALL Hub @ALL_Hub_]

CONGRESS #EHA2024 | Sujith Samarasinghe @GreatOrmondSt shares initial findings from the phase II ALLTogether1 DS trial evaluating blinatumomab as chemotherapy-replacement for children and young adults with Down Syndrome B-cell ALL (N=33). The primary endpoint was met, with 91% patients being MRD undetectable at the end of cycle 1. Grade 3/4 toxicity events were significantly lower compared to UKALL 2011 trial. No deaths, relapse, or secondary cancer were reported, however, a higher rate of seizures was observed. #ALLsm #leusm #MedicalCongress

[Ångus Hodder @AngusHodder]

@CRUKresearch Whoop

[andi roy @andiroy]

Many thanks to @CRUKresearch and @GOSHCharity for funding this project. We are a team of clinicians, parents, scientists and data analysts working together #TeamScience. @DrJackBartram @milnetom68 Andrew Blake @OxfordOncology and many more collaborators. Can’t wait to get started

[Jack Bartram @DrJackBartram]

Goodbye multi-header microscope, over 25 years of service in @GreatOrmondSt Haematology lab. Countless lives saved, diagnoses made and educated thousands. You never complained once. Happy retirement. 🩸🔬

[Sara Ghorashian @sghorashian]

Pilot data supporting a role for maintenance chemotherapy following early B cell recovery after CART for B-ALL in transplant ineligible patients. Needs longer follow up and prospective study. Thanks to Maria Gabelli and @maca_moe_

[Sara Ghorashian @sghorashian]

Featuring our very own Dr Sujith Samarasinghe!

[BBC News (World) @BBCWorld]

Exciting new cancer drug kinder than chemotherapy https://t.co/cS5k3uO0kq

[Ångus Hodder @AngusHodder]

Great publicity this am https://t.co/x6ZIVyEdQU
from our @JCO_ASCO paper (https://t.co/78zdRxz889)
🫵Blina is safe+effective chemo-replacement for chemo-intolerant children
❓Now how should Blina be used for all children with B-ALL?

[Leukaemia UK @LeukUK]

Great to see a kinder, less toxic treatment option available for some children with B-ALL.

Blinatumomab has less side effects than standard chemotherapy and is fully portable, meaning it can be given on the go and patients spend less time in hospital. 👏
https://t.co/LD9iJcF9P8

[David O'Connor @drdavidoconnor]

Just out in @BloodJournal – our study exploring the origin of late relapses in T-ALL. Here's a short thread with our unexpected results!

https://t.co/bWACBlepRb

[Joshua Fein @joshuaafein]

Okay - updated version, now easily browsable. https://t.co/rOFfDYCkGi This is a pdf of #ASH23 abstracts (no figures, but URLs). Organized by session, so you should be able to find something interesting by ctrl-F and then browse from there. Cover art by DALL-E. Caveats below

[andi roy @andiroy]

Last few days to apply!