Gracias @Leo___Lagos por la nota sobre nuestro trabajo: ciclopéptidos naturales como herbicidas e inhibidores de cianobacterias (Cyclopeptides Natural Products as Herbicides and Inhibitors of Cyanobacteria: Synthesis of Versicotides E and F)
En esta nota contamos como un grupo de químicas juntan fuerzas con un hongo marino para enfrentar a los agrotóxicos y a las cianobacterias al mismo tiempo. Brillante trabajo de @anth_LP, Gloria Serra y muchos colegas más.
https://t.co/VcOwldrOIC
BREAKING NEWS
The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.
Paper Alert🚨 @PeterChemBio1 group has developed the first cell active inhibitor of #mRNA deadenylation. Published in @angew_chem congrats to @SunitPal_HBS et al.
https://t.co/eswS2moqFo
#SobreCiencia » Productores exterminan plagas pero también polinizadores con productos tóxicos.
🗣️: “Hay que saber bien cómo funciona el sistema para hacer manejos que minimicen el uso de agroquímicos”, dice Carmen Rossini, co-responsable del Lab. de Ecología Química @FqUdelar.
🏆Felicitamos a la Dra. Cecilia Saiz, ganadora del 16º Premio L’Oréal Unesco “Por las Mujeres en la Ciencia” de #Uruguay.
Más información: https://t.co/iQojRF53ZO
Another successful result of our unique & fruitful collaboration with @AstraZeneca :
N-Biphenyl Pyrrolinones & Dibenzofurans as RNA-Binding Protein LIN28 Inhibitors Disrupting the LIN28–Let-7 Interaction | ACS Med. Chem. Lett. - published by Wu lab (CGC) https://t.co/rjEdGceR3F
Dynamic Phosphorus!
Our new paper in @angew_chem introduces phosphorus V as exchange center in dynamic covalent cascade processes, simulating molecular walkers to find new ways to enter or prevent entry into cells.
https://t.co/rkxse3TdOy
Great Evening spent at @mpimoph most awaited Diwali celebrations 🎉 nicely organised by the Indian community and fully backed up by others 🤩 great food and lots of fun activities ☺️
Validation of a New Methodology to Create Oral Drugs beyond the Rule of 5 for Intracellular Tough Targets | Journal of the American Chemical Society #Lipinski#Ruleof5#OrallyAvailable#Drugs#Protein#KRAS https://t.co/7QfIzG2R6o
Fantastic work led by Zhou in our group, see below his facile semisynthetic method for fluorescent tools which paved the way for an in-depth understanding of SUMO specificity and revealed some more secrets about my favourite DUBs (USP36 and USP16). @MalteGersch@mpimoph@J_A_C_S
I am very much looking forward to this virtual event on October 4th and to sharing the screen with @AlannaSchepartz, @NinaHartrampf & Herbert Waldmann. Thank you, @ChristianAOlsen, for the invitation. If you are interested, you can register for free!
Unprecedented hydrophobic peptides by incorporation of an SCF3 group either directly to an aromatic amino acid followed by SPPS, or by Trp-selective late functionalization of peptides. See the #JOrgChem article by @JureGregorc et al https://t.co/oNVcelAD1X @BioCIS@IskraJernej
#SAMURI is a new #ribozyme for RNA-catalyzed labeling of RNA. It uses a new cell-permeable SAM analogue and generates a novel propargylated nucleotide in RNA. Check out the full story https://t.co/Y4yPDxe3oI
https://t.co/XRzE1CdcpY
Today our preprint on the development of a synthesis tag (SynTag) for chemical protein synthesis came out on ChemRxiv: https://t.co/01ZTI7GnwO 🥳
@Hartrampf_Lab @elysetwilliams @AlienorJeandin@UZH_Chemistry
María Méndez Pérez @sanofi with an unusual example of structure-based design: custom-build binders to albumin for generating novel long-acting variants of insulin to treat diabetes. #EFMCASMC23@EuroMedChem