Bio2Byte

We investigate how the dynamics, conformational states and available experimental data of proteins relates to their amino acid sequence.

[Bio2Byte @Bio2Byte]

Bio2byte is excited to welcome our new master's students!
Golnar Chapnevis, Arathy Uday, Ayda Azadegan, Melika Seirani, Tutku Ekin Bayrı, and Nigel Wens.
Wishing you all the best as you embark on your exciting thesis projects. Good luck 👏🏽

[Bio2Byte @Bio2Byte]

Our recent work on predicting the #cancer driver #mutations combining the evolutionary information and protein language model (#plm) is out in Biorxiv.

https://t.co/IVmLwX7wYF

[Bio2Byte @Bio2Byte]

Spatial proteomics in the context of #protein #modifications, #structure #function and #dynamics. Visit @Pathmanaban_'s poster this evening at the #BSPREUPA2023 Congress.

[Pathmanaban Ramasamy @Pathmanaban_]

Working in #spatial #proteomics?
Like to know how the post-translational modifications (#ptms) of #proteins varies between and within #tissue types?
Wondering how does that compare with the protein #behavior?

Find the answers at my poster (# 152) in #BSPREUPA2023 conference.

[Pathmanaban Ramasamy @Pathmanaban_]

At #ASMS2023 and interested in Post-translational modifications of proteins? Feel free to join me this afternoon where I will be talking about my recent work on #tissue specific #PTM maps in #human #proteome. Especially on tissue specific protein #phosphorylation.

[Bio2Byte @Bio2Byte]

Registrations are open! Check the link below. #Challenges and #opportunities in #AI based research in #hospitals.

[icity.brussels @icity_brussels]

🔥Join us on October 6th🆓Register now!👉https://t.co/fJyRmGVLvY
🖥 Wim Vranken will present the TumorScope project, which strives to overcome the amount, complexity, & protection of health-related data & to stimulate innovation in the #AI-driven interpretation of #patientdata.

[Bio2Byte @Bio2Byte]

At Today's poster session @ECCBinfo David will present his work on large scale conformational dataset, that links the #peptide #sequence and #phosphorylations to changes in backbone conformations and #dynamics.
Poster number: P189-T
Track: Proteins
#ECCB2022

[Bio2Byte @Bio2Byte]

Hello #ECCB2022. Don't forget to check Sophie's poster this evening. Sophie will present her poster on "Using #AlphaFold2-generated #structural information to improve detection of #evolutionary adaptations in #proteins".
Poster number: P150-T
Track: Genomes
@ECCBinfo

[Bio2Byte @Bio2Byte]

@Pathmanaban_ from our group will present his work on "Tissue specific protein modification map of the human proteome. He will explain about the tissue specific patterns on protein #ptms both at protein and at site level. Interested? Please visit his poster "P008-M" this evening.

[Bio2Byte @Bio2Byte]

@joelrockm from our group will present his poster at #ECCB2022 @ECCBinfo on "Deciphering the RRM-RNA recognition code: A computational analysis". If you are working on protein-RNA interaction, please do stop by at poster number P187-M this evening.

[Bio2Byte @Bio2Byte]

At #ECCB2022? Check @GavaldaGarcia's poster P181-M.

Jose from our group will present ConforMine, a predictor of protein #Conformational
Variability from amino acid #sequence. His poster features an explanation of both the #biophysical basis and the estimator for this metric.

[Bio2Byte @Bio2Byte]

Hope everyone is having an amazing day at @ECCBinfo #ECCB2022. Here is our @Bio2Byte delegation with interesting topics. Don't forget to pass by our poster stands. Looking forward to meeting you.

[Bio2Byte @Bio2Byte]

@ECCBinfo #ECCB2022

[Jose Gavalda-Garcia, PhD @GavaldaGarcia]

First talk by our group leader @wim_vranken at #ECCB2022 for his @ELIXIREurope talk

[Bio2Byte @Bio2Byte]

Hello #ECCB2022, In today's Session#1 under #ELIXIR @ELIXIREurope track, Wim Vranken will be talking about the resources and synergies between three ELIXIR communities; #proteomics, Intrinsically disordered proteins(#IDPs) and 3D-#Bioinfo at Auditorium Anna Tramontano at 10 AM.

[Bio2Byte @Bio2Byte]

#Scop3P an @ELIXIRnodeBE service developed by @Pathmanaban_ in collaboration with @compomics, links human phosphorylation sites with protein structures and biophysical characteristics. Check the link below and give it a try! Feedbacks are welcome.

[ELIXIR Belgium @ELIXIRnodeBE]

📢Scop3P provides a unique and powerful resource for researchers to explore and understand the impact of phospho-sites on human protein structure and function.
✅Why not try it out? https://t.co/KWlSpMvZ1n 🔗

#bioinformatics #openscience #opensource #DataScience @ResearchSoft

[Bio2Byte @Bio2Byte]

Another interesting perspective on highly dynamic and/or structurally ambiguous behavior of protein regions and the challenges involved in describing these ambiguous regions from the biophysical aspects.

[Tamas Lazar @LazTamas]

We're glad to share our latest publication on the challenges in describing the conformation and dynamics of proteins with ambiguous behavior, authored among others by @JoelRockM @LazTamas @GavaldaGarcia @KTzavella @Pathmanaban_ @Grau_Isel and @Wim_Vranken:
https://t.co/xRK9qx8725

[Bio2Byte @Bio2Byte]

RNAct conference tailoring RNA binding proteins and RNA targeting. September 14 and 15 in Valencia, Spain. Register here: https://t.co/l4q14zM95V

[Wim Vranken @wim_vranken]

Protein-RNA interactions are essential - the RNAct MSCA-ITN conference (14-15/09/22, Valencia, Spain), focusses on how proteins bind RNA, and how we can tailor RNA binding proteins for synthetic biology and biosensor development - register at https://t.co/gnz2RvYzAS! @eu_rnact

[Journal of Proteome Research @JProteomeRes]

Using the wealth of available phospho-proteomics #MassSpec data, the @compomics & @Bio2Byte labs demonstrate the advantage of data reprocessing for a more reliable & comprehensive view of proteome-wide P-sites. https://t.co/PKJZHthD8C

[Bio2Byte @Bio2Byte]

Our recent work shows an interesting view on the reliability of #protein #phosphorylation sites from other gold standard resources when compared to re-processed data from #Scop3p. Also shows their possible impact on #structures, functional #domains and #biophysical properties.

[Pathmanaban Ramasamy @Pathmanaban_]

Are you working on #protein #phosphorylations (#PTMs)? Ever wondered where these modifications are occurring on protein #structures and how that would affect their biophysical properties, structural transitions and #mutations?
Then this is for you!
https://t.co/IHk3Z4Iq1o

[Bio2Byte @Bio2Byte]

Workshop on AI based solutions for health care. Together with @imec_smit. More details in the thread.

[imec-smit, VUB @imec_smit]

What are challenges around the #development and #implementation of clinical #AI solutions? 🏥

SMIT researcher Lawrence Van den Bogaert will present on #AI for #healthcare on the 15th of June.

Registration link : https://t.co/Jgt2VuuCI8

[Bio2Byte @Bio2Byte]

Excellent work from one of our PhD student @Pathmanaban_ showing how re-processing of public #proteomics data can help identify reliable P-sites and the possible dynamics involved in protein phosphorylation.

[Pathmanaban Ramasamy @Pathmanaban_]

We present a large scale integrated approach to understand the #human phosphosites and phosphoproteins by placing them in a variety of possible contexts such as #sequence, #structure, #disorderedness and #biophysical properties.

https://t.co/1UJoNM9i38