@GermHunterMD @MadyHeldman@JoshuaHillMD@fredhutch The “glass half empty” point of view would be that even close to the day of diagnosis, sensitivity for invasive aspergillosis was still only 38%, comparable to serum galactom. Advantage probably more in the rare fungi, or when standard diagnostic tests (including PCR) negative?
Wij zoeken een nieuw hoofd voor de Medische Microbiologie & Infectieziekten waar zoveel geweldige collega’s met veel plezier samenwerken in zorg, onderzoek, onderwijs en opleiding. @NVMM_NL @HeimanW @JulietteSeverin https://t.co/Gvwg5At8a1
@sarah_delliere Yeh, and in the invitation we get to write an article for the issue of our nationality, we will get a fantastic 50% lower publication fee (which still is like 1500 euro).
@mkeulemans@UniUtrecht Als infectioloog in Erasmus MC van 2020-22 fulltime met covid patienten en onderzoek in de weer geweest. In de volgende decennia zie ik de klimaatcrisis als een grotere bedreiging dan een volgende pandemie. Noodtoestand lijkt me dus goede woordkeuze.
@DrMJoyner@onepeloton Wow, not bad at all. Will post my very boring flat curve of a 4 hour training on zwift tomorrow while watching the last 4 hours online of “The tour of Flanders” UCI monument raise. It is the biggest sporting event of the year in Belgium, 1.000.000 spectators along the 273 km ride
1/5 Hey @Apple and @EU_Commission, In our family of 5, we bought 3 Apple MAC computers over the last 15 years. Now also the most recent one no longer receives OS updates (and as a result also no MS Office updates). This has nothing to do with “an outdated slow computer”...
4/5 When will the EU oblige Apple to guarantee OS updates for at least 15 years for operating systems, when the hardware and processor is not at all outdated (and demand that Apple explains their customers what part of the hardware has to be updated to get OS updates again.
@GermHunterMD @SammyHuygens@jochembuil Thanks for posting. No simple conclusions to be made. All depends on perspective one takes. Looking at patients in whom A.fumigatus was detected and resistance PCR succesful, 14% had azole resistance. But looking at the n=293 population undergoing BAL and PCR, it was 3%.
@EricTopol@BramanteCarolyn For a sec endpoint, even predefined I would not dare to conclude effectivity for long-covid. The more because there are now have been so many intervention trials on covid that a statistical finding at P0.01 for a secondary endpoint means even less. Hypothesis generating perhaps.
@mkeulemans@persveilig Ik denk dat ze Chatgpt gebruiken om dit soort idiote reacties te posten want inhoudelijke argumenten schrijven is wat te ingewikkeld voor ze. Ga biljarten Keulemans komt van iemand met Belgische wortels en wel weer grappig dus niet IA. Raymond Ceulemans was meervoudig WC 3-banden
As an example; after phase 1/2 trials are completed, pivotal phase 3 trials on new antifungal drugs typically take another 3 to 5 years to complete (5/8)