BroadPharm

BroadPharm is a worldwide leading supplier of high quality PEG Linkers, Click Chemistry, Dye Labeling and Biotin Labeling reagents. #biotech #ClickChemistry

[BroadPharm @BroadPharm]

Our latest blog post explores the world of phosphoramidites, the building blocks of oligonucleotide synthesis. Dive in now: https://t.co/PM6HwdbL7s #Phosphoramidites #OligonucleotideSynthesis #ResearchAdvancements

[BroadPharm @BroadPharm]

Maximize the potential of #Lipids in Drug Delivery! Read our latest blog to discover the science behind this innovative method. A must-read for all in the #biotech and #mRNA vaccines. 💊📚 #InnovativeResearch #research

https://t.co/pbDHr2yXtv

[BroadPharm @BroadPharm]

Scientists used a maleimide-PEG linker to conjugate a drug to a peptide. The maleimide end reacted with cysteine residues, binding the peptide to a PEG linker loaded with the imatinib drug

Check out our supply of PEG linkers today: https://t.co/nqNp9kTrOg

#biochemistry #biotech

[BroadPharm @BroadPharm]

One click chemistry reaction that has gained recognition in recent years is the trans cyclooctene/tetrazine (TCO/Tz) reaction. Using this reaction, one can perform bioorthogonal chemistry. Checkout our supply today!

Catalog: https://t.co/kCJpXQ4Shb

#biotech #science #research

[BroadPharm @BroadPharm]

Here at BroadPharm we are excited to offer over 500 high purity Click Chemistry Reagents (tools) and Kits. We are here to support your research needs. Check out our selection today! https://t.co/EWE8pb1Wwe

[Chemistry World @ChemistryWorld]

‘A new age of chemical interrogation of complex biological systems awaits’ – The 2022 Nobel prize in chemistry has been shared equally between click chemistry pioneers Morten Meldal and Barry Sharpless, and bioorthogonal chemistry founder Carolyn Bertozzi
https://t.co/IQuenaFMUG

[BroadPharm @BroadPharm]

Branched PEG is a class of multi-arm PEG linkers. Molecules with multiple payloads & targeting moities can be constructed to increase drug-antibody ratio. The increased size also increases half-life in vivo and reduces nonspecific degradation.

Catalog: https://t.co/y3go7FFoNB

[BroadPharm @BroadPharm]

Ionizable lipids are neutral at physiological pH & protonated at acidic pH. Because of this, they provide effective RNA delivery by protecting RNA from degradation and assisting in cytosolic transport.

BroadPharm offers a variety of lipids here: https://t.co/t7NGEsyi8r

#biotech

[BroadPharm @BroadPharm]

Ionizable lipids are organic molecules that are neutral at physiological pH & protonated at acidic pH. 5 types of ionizable lipids used in RNA delivery: unsaturated, multi-tail, polymeric, biodegradable, & branched-tail.

Catalog: https://t.co/t7NGEsyi8r

#Chemistry #Lipids #mRNA

[BroadPharm @BroadPharm]

#TargetedTherapy #CancerResearch #Biotech #PROTAC #Research

[BroadPharm @BroadPharm]

Proteolysis-targeting chimera (PROTAC) protein degraders are heterobifunctional small molecules consisting of two ligands joined by a linker. One ligand recruits and binds a protein of interest while the other ligand recruits and binds an E3 ubiquitin ligase.

[BroadPharm @BroadPharm]

We offer PROTAC products such as BET inhibitors, E3 ligase ligands, and PROTAC linkers of various lengths to facilitate your research needs. Our catalog can be found here: https://t.co/DaiBBjaTRK. For more info, contact us at [email protected] call us at [phone].

[BroadPharm @BroadPharm]

Did you know the surface charge of a lipid nanoparticle influences what organ is targeted? A neutral charge targets the liver, negative charge targets the spleen, and positive charge targets the lungs!

Browse our catalog of ionizable lipids here: https://t.co/YXNuaDFVQ8

[BroadPharm @BroadPharm]

Click Chemistry is utilized in drug development, bioconjugation, and labeling in mild conditions and inert to naturally occurring functional groups. Check out our catalog of products here: https://t.co/TBfLcZre8r

#biotech #chemistry #pharmaceutical

[BroadPharm @BroadPharm]

We launched our MagicLink kit for biomolecules conjugation. These kits include oligo, HRP and alkaline phosphatase antibody conjugation kits, streptavidin conjugation kit, and protein-protein crosslinking kit, APC, and PE conjugation kits.

Link: https://t.co/owI9wkpTiT

[BroadPharm @BroadPharm]

Take a look at our catalog of in stock ionizable lipids here: https://t.co/YXNuaDFVQ8

[BroadPharm @BroadPharm]

Ionizable lipids are a class of lipid molecules which remain neutral at physiological pH, but are protonated at low pH, making them positively charged. SM-102 is an example with the amine site that can be protonated at low pH.

#Lipids #Science #Biotech #LipidNanoparticle #mRNA

[BroadPharm @BroadPharm]

BroadPharm is widely known as the leading supplier of monodisperse polyethylene glycol (PEG) linkers, but BroadPharm also sells PEG polymer compounds to aid in your R&D and production needs.

Browse through our PEG catalog here: https://t.co/HcXpsFy6lT
#pegpolymers #science

[BroadPharm @BroadPharm]

BroadPharm’s MagicLink™ protein conjugation kit (https://t.co/NluvEReQLf) is based on the 3rd generation crosslinking tech and PEG chemistry. MagicLink can link two biomolecules such as proteins, antibodies, nucleic acids for applications such as FC, ELISA, WB, etc.
#biotech

[BroadPharm @BroadPharm]

Lipid nanoparticle delivery attracted tremendous attention with its success in delivery of mRNA in the #Covid19 vaccine. We developed a series of lipids such as cationic, ionizable, helper, pegylated, & branched lipids which can be found here: https://t.co/kgjHy3d7Qs.
#science