Bruning Structural Lab

Research lab at the University of Adelaide with a focus on structural biology, protein chemistry, drug discovery, and enzymology

[Bruning Structural Lab @BruningLab]

Was lucky to meet up with former PhD students from BruningLab: Andrew Marshall (UWA), Andrew Thompson (Oxford/WEHI) and Jordan Pederick (UA)

[Bruning Structural Lab @BruningLab]

Congratulations @StephNguyenPhD and good luck on all future protein preps. I’m sure there will be many.

[Stephanie Nguyen @StephNguyenPhD]

Ayyy the letter has arrived! Ya girl is officially #PhDone A quick moment of celebration in the lab before I get back to my protein prep 🥲 @UniAdelSciences @BruningLab

[Bruning Structural Lab @BruningLab]

Congratulations Dan on delivering a great poster! Very well deserved!

[Bruning Structural Lab @BruningLab]

A brand new review written by @FrkicRebecca sheds light on how we can treat type 2 #diabetes by inhibiting PPARy phosphorylation

[Journal of Biological Chemistry @jbiolchem]

"The therapeutic potential of inhibiting PPARγ phosphorylation to treat type 2 #diabetes"

@UniofAdelaide @FrkicRebecca #JBCReviews #drugdesign

https://t.co/TVCffCQ8JI

[Bruning Structural Lab @BruningLab]

Some fantastic work from @acmarshallphd from his time in Adelaide

[Andrew C Marshall @acmarshallphd]

By tweaking this #enzyme in only a handful of places we made it activated by K+ ions… some #proteins are remarkably engineerable! @BruningLab https://t.co/nGgjTzmkVy... (1/3)

[Stephen Bell @BellP450Chem]

Latest work from the lab is published
https://t.co/juKAUEq6QE
#biocatalysis, #ozchem, #P450s
Lead by Master students Rebecca @RebeccaChao29 and Ian @LordOfSpatulas
@AdelaideChem
@UQ_SCMB

[RSC Chemical Biology @rsc_chembio]

🔥 New advance article for RSC Chemical Biology! 🔥 Andrew Abell, @BruningLab et al @UniofAdelaide exploring a cell permeable bimane-constrained PCNA-interacting #peptide! #chembio #bimane

🧐 Read the #TransparentPeerReview #OpenAccess article 👉https://t.co/knfdpXpFW5

[Bruning Structural Lab @BruningLab]

That’s a wrap for @StephNguyenPhD who gave her completion seminar last week. She’s off to @WEHI_research to continue on her structural biology journey. Best of luck!

[Dr Blagojce (BJ) Jovcevski @BJJovcevski]

It's been an absolute pleasure having you @StephNguyenPhD as a student with the @BruningLab ☺️ Super happy for you!!! @WEHI_research is going to be very lucky to have you!!! 🎉🎉💪💪

@AdelaideProtein @UniAdelSciences

[Bruning Structural Lab @BruningLab]

Exciting work coming from @StephNguyenPhD. Read the preprint on @biorxivpreprint!

[Stephanie Nguyen @StephNguyenPhD]

So excited to be part of this work on #SARSCoV2. Available to read on @biorxivpreprint! https://t.co/p797jGIvzd

[Stephanie Nguyen @StephNguyenPhD]

Another year, another synchrotron trip! ⚡️💎

[Stephen Bell @BellP450Chem]

New work from My lab and collaborators at UQ on understanding the mechanism of stereoselective P450 catalysed epoxidations
https://t.co/Fu6zgObIz1
#ozchem #P450 @AdelaideChem @UQ_SCMB

[Bruning Structural Lab @BruningLab]

A comprehensive review written by @StephNguyenPhD and @TruongJia - an interesting read for #antifungal enthusiasts

[Stephanie Nguyen @StephNguyenPhD]

Aaand it’s published! I’ve written a review for @FrontMolBioSci with @TruongJia and @BruningLab that discusses exciting and unconventional fungal 🍄 pathways we could be targeting in our search for new #antifungal #drugs 💊

https://t.co/VWznarmHna

[Bruning Structural Lab @BruningLab]

Some fresh #aspergillus research from @StephNguyenPhD published in @FEBSJournal - a tremendous amount of work to elucidate the structural determinants of nucleoside selectivity of the enzyme, nucleoside-diphosphate kinase

[Stephanie Nguyen @StephNguyenPhD]

My 1st first author paper is out! A paper I’m so proud of because I learnt everything I now know about crystallography from this protein 💎 big thanks to our collaborators @blagojce11 @PukalaLab @BruningLab

https://t.co/JjKVlQJwTb

[Bruning Structural Lab @BruningLab]

Congratulations to @FrkicRebecca on submitting her PhD thesis! Wishing her all the very best for the future 💕

[Rebecca Frkic @FrkicRebecca]

I have just submitted my PhD thesis at @UniofAdelaide! Shout out to those legends who have made my experience amazing. This journey has been so incredible and I am so excited for what is next to come!

[Bruning Structural Lab @BruningLab]

A snapshot of some of the exciting projects we have been working on using #proteincrystallography

[Bruning Structural Lab @BruningLab]

A new publication from @StephNguyenPhD from her time in the Booker Lab that started her work on #fungi and #antifungals with Dr. Sternicki and Dr. Polyak. Check it out!
https://t.co/qEzjr3SPig

[Bruning Structural Lab @BruningLab]

Soaking up some sun and enjoying Christmas lunch with the Bruning family 🌲☀️

[Bruning Structural Lab @BruningLab]

@MichelleCouls18 Adorable! We love it 😍

[Bruning Structural Lab @BruningLab]

@aimeehorsfall You spent weeks purifying PCNA. YOU’RE ONE OF US NOW.

[Bruning Structural Lab @BruningLab]

An insightful review written by @aimeehorsfall from #AbellGroup for anyone interested in #peptidomimetics, cancer therapeutics and #PCNA

[ChemBioChem @ChemBioChem]

Targeting PCNA with #peptidomimetics for therapeutic purposes (@BruningLab @UniofAdelaide) #drugdesign #cancer https://t.co/fosDG4BOvN