BTX

BTX Harvard Apparatus develops and manufactures electroporation and electrofusion equipment, cuvettes, electrodes and buffers for life science research.

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Researchers at Texas A&M University have created a simple, scalable method for phage display Fab library creation using the BTX ECM 399. Read the paper here: https://t.co/I1eNUQt3B4

#antibodies #drugdiscovery #electroporation

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A variant Cas9 nuclease and cell cycle synchronization increased precise homology‐directed repair (HDR) relative to error‐prone nonhomologous end joining (NHEJ) in human hematopoietic stem cells (hHSC) in a model of sickle-cell disease: https://t.co/E46agx9ocQ

#sicklecelldisease

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A new proteomics based approach has been used to study the altered molecular mechanisms during inactivation of pathogenic bacteria in food products sterilized using Pulsed Electric Field (PEF) aka electroporation: https://t.co/k8nb6dDsDK

#proteomics #foodsafety #electroporation

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Melatonin can help you get a good night’s sleep, but a new study shows it may also help embryos overcome oxidative stress during electrofusion SCNT (using the ECM 830 generator and BTX cytofusion medium C). Read the paper here: https://t.co/k0AHxXtdMG

#CRISPR #oxidativestress

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The specificity of anti-sense oligonucleotides (ASO) such as siRNA, and CRISPR guide RNA (sgRNA) is critical to their effectiveness, either as a therapeutic or a research tool. See how off target effects of ASOs are being empirically studied in this paper: https://t.co/ZqIqN73qLF

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Learn how electroporation is enabling researchers to create modified bacteria that can produce clean hydrogen biofuel. Read our new blog here: https://t.co/br0UtQ1ZnL

#electroporation #biofuels #cleanenergy

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Happy National Ice Cream! Did you know the BTX ECM 830 was used to create an ice cream enriched with calcium-loaded probiotic bacteria to slow melting rates? Read the paper here: https://t.co/6287ssPpsj

#nationalicecreamday #calcium #probiotic

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Plasmid DNA vaccines delivered with BTX ECM 830 electroporation show enhanced tissue specific targeting of T and B-cells when adjuvants that include cytokines or chemokines are added. Read the paper here: https://t.co/zvoXLW9p1j

#immunization #dnavaccines #electroporation

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Happy 24th birthday to the very first cloned sheep, Dolly! The somatic cell nuclear transfer process that created Dolly utilized an electrofusion generator like the BTX ECM 2001. Read the original publication in Nature here: https://t.co/wCzJsGRsps

#dollythesheep #happybirthday

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Researchers have created a new large mammal model for Hemophilia B. This can be used for both pharmaceutical and gene therapy development. Read the paper here: https://t.co/yHQM7NFTEG

#genetherapy #drugdiscovery #hemophilia

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We offer solutions for cell fusion and mammalian electroporation to fit your needs. Learn more about the NEW ECM 2001 LITE and the ECM 2001 +here: https://t.co/LBMPEDDial

#electrofusion #electroporation #cellengineering

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Electrofusion offers an efficient, reliable, and scalable monoclonal antibody production process for biologic drug discovery or life science research applications. Download our Hybridoma Application Note here: https://t.co/S283J70aTa

#biotech #hybridoma #drugdiscovery

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Learn about a high-efficiency method to transform Chlamydomonas reinhardtii. Read our new blog here: https://t.co/QWPusu8re8

#electroporation #cellbiology #chlamydomonas

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Join us at the 2020 American Association for Cancer Research (@AACR) Virtual Meeting. Click here for meeting information and free registration: https://t.co/Xh0WKphuRT

#AACR2020

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Electrochemotherapy with the BTX ECM 830 and curcumin (a yellow pigment from the tumeric plant) enhanced apoptosis of triple negative breast cancer cells + downregulated key metabolic pathway proteins. Read the paper here: https://t.co/MT2QSEV9UG #electroporation #cancerresearch

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Researchers at Elon University, supported by the Gates Foundation 'Reinvent the Toilet Challenge,' are using the BTX ECM 830 electroporator to deactivate parasitic worms and eggs in wastewater. Check out their poster here: https://t.co/WlSz5EimDg

#electroporation #wastewater

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Learn how electroporation is being utilized in vaccine research to direct the body’s immune system to attack melanoma Cancer cells. Read our new blog here: https://t.co/8xjJpWhMl3

#vaccine #cancerresearch #electroporation #immunology

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Researchers at Vanderbilt University use hybridoma-producing technologies such as the BTX ECM 2001 Electrofusion Generator to make monoclonal antibodies as potential treatments to treat COVID-19. Learn more about antibodies targeting SARS-CoV-2 here: https://t.co/PFx8LcEbZZ

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ECM 630 was used in assays to study the role of putative methyltransferase MtrP in the cell wall synthesis pathway. MtrP may be a new drug target for Mycobacterium and Corynebacterium which cause tuberculosis and diphtheria. https://t.co/AOJr4sksIi #electroporation #microbiology

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Did you know that there is a free comprehensive protocol database for #electroporation and #electrofusion research? We offer over 1,000 protocols searchable by instrument, cell/tissue type, application/transfectant, and citation here: https://t.co/gRPmMKcdAA #transfection