Travis Wiles

Exploring the unseen connections between animals and the microbial world. 🦠🧫🧬🔬🐟🧪💊

[Travis Wiles @bunsen_B]

@implosian @baym @HealthNYGov Wow! Awesome Siân, congrats!

[Travis Wiles @bunsen_B]

Check out the rest of the preprint to see the coolest aspect of Phollow: tracking interbacterial transmission!

[Travis Wiles @bunsen_B]

Posting some of the amazing movies captured by first author @christianlizett that can be found in our recent preprint...

[bioRxiv Microbiology @biorxiv_micrbio]

Phollow: Visualizing Gut Bacteriophage Transmission within Microbial Communities and Living Animals https://t.co/vTzKognIii #biorxiv_micrbio

[Travis Wiles @bunsen_B]

...and it was incredible to find that enteroendocrine cells (green in this movie) appear to quickly internalize phages, or debris from cell lysis (white). pink = nuclei of intestinal tissues.

[Travis Wiles @bunsen_B]

First preprint from the Wiles Lab! We used an approach we call "Phollow" to study phage replication and transmission by live imaging!

[bioRxiv Microbiology @biorxiv_micrbio]

Phollow: Visualizing Gut Bacteriophage Transmission within Microbial Communities and Living Animals https://t.co/vTzKognIii #biorxiv_micrbio

[Travis Wiles @bunsen_B]

@tinoco_lab @UCIBioSci @UC_PPFP @SD_IRACDA @MelanomaReAlli @NIAIDFunding @DeptofDefense LET'S GO! Awesome news!

[Travis Wiles @bunsen_B]

Radiant bacteria by @christianlizett

[Travis Wiles @bunsen_B]

@QuinaScience @Starbucks Silvia gets the best drinks!

[Travis Wiles @bunsen_B]

@NkrumahGrant 🙌

[Travis Wiles @bunsen_B]

@zebragut So far, not with this strain.

[Travis Wiles @bunsen_B]

Grad student Courtney Knitter captured this electric image of a Vibrio species (magenta) colonizing the zebrafish gut. Cyan marks cells of the zebrafish that are producing inflammatory signals.

[Travis Wiles @bunsen_B]

@JasenkaPhd Oh, yes! They are expressing dTomato!

[Travis Wiles @bunsen_B]

@JasenkaPhd A fluorescence stereo microscope 🙂

[Travis Wiles @bunsen_B]

@JasenkaPhd @christianlizett Nope, just for fun (for now😬)

[Travis Wiles @bunsen_B]

��such fun images of 3 member E. coli communities in the zebrafish gut by postdoc Liz Ortiz! @christianlizett

[Travis Wiles @bunsen_B]

@DesbanLaura Or at least maybe these neurons…https://t.co/uH8sMNPOJr

[Travis Wiles @bunsen_B]

@DesbanLaura Actually TNF:GFP…those are DRGs I believe

[Travis Wiles @bunsen_B]

So inspired by my recent trip to New Hampshire for the @GordonConf on Microbial Population Biology…was able to grab a bike and roll some gravel too!