Carl Moons

Epidemiology;UMCU;Cochrane;Health Innovation Netherlands (HiNL);Center for Side Effects Implants;Prediction Models;Medical tests&apps;Chief Editor Diag&Prog Res

[Carl Moons @CarlMoons]

@EllaFlemyng @Richard_D_Riley @cochranecollab Thanks Ella and colleagues for making this great endeavour within Cochrane possible!!!

[Carl Moons @CarlMoons]

We agree and work hard to have the handbook out at the end of 2024

[Fannie Apostolidou Kiouti @f_apostolidou_q]

@Richard_D_Riley @AlbertoEMaraolo @CarlMoons Can't be too soon!

[Richard Riley (R²) @Richard_D_Riley]

And @CarlMoons showcasing the handbook at #cochranelondon

[Ella Flemyng @EllaFlemyng]

And then there was prognosis! @CarlMoons @Richard_D_Riley
introducing the new #CochranePrognosisHandbook - our youngest in the @cochranecollab Handbook family with 1st chapters due in late 2024

[TRIPODStatement @TRIPODStatement]

COMING SOON -> Draft TRIPOD+AI checklist & paper on recommendations for reporting #ArtificialIntelligence studies driven by #MachineLearning and #Statistics for healthcare out with co-authors for comments.

#gettingclose #transparency

[Gary Collins @GSCollins]

Among the many important recommendations in the UK House of Commons report on Reproducibility and Research Integrity, recommendations 11 and 12 are resonate 👇

--> https://t.co/jrtGl2ZBDC

#statstwitter #methodsmatter #notohobbystatisticians

[TRIPODStatement @TRIPODStatement]

We're seeing lots of reviews of prediction models, particularly as a consequence of lots of machine learning studies

So we've developed some reporting recommendations for systematic reviews / meta-analyses of prediction models

https://t.co/9LFLJM67lS

#openaccess #statstwitter

[Gary Collins @GSCollins]

@Zaks1000 @Kym_Snell @bmj_latest @blevis_epi @Richard_D_Riley @CarlMoons @TPA_Debray @hans_reitsma @pauladhiman No this is a different reporting guideline (for systematic reviews of prediction models)

TRIPOD+AI is coming...

[Carl Moons @CarlMoons]

It is indeed - and the paper that shows that is almost out as well.

[Abel Torres Espin @AbelTorresEspi2]

@pauladhiman @GSCollins @DrGSBullock @Richard_D_Riley @BenVanCalster @BenjaminSpeich @CarlMoons @CSMOxford Great work. I have my suspicion this is not only in oncology but generalized across medicine and health, unfortunately

[Maarten van Smeden @MaartenvSmeden]

Are you a prediction modeling expert and not yet invited to participate in the Delphi of PROBAST+AI, we would love to hear from you!

Send me a DM with your name and email, and I'll get you a personal invitation link

[Carl Moons @CarlMoons]

A great overview of methodological aspects that may still need to be improved when developing machine learning or AI based prediction models for diagnosis, prognosis, prevention or monitoring. Thanks to many colleagues who made this tremendous amount of work possible.

[Gary Collins @GSCollins]

NEW PAPER in @JClinEpi -> "focus is required on handling of missing values, methods for internal validation, & reporting of calibration to improve [...] studies on #machinelearning-based prediction models" https://t.co/WCDEkIpkbj

#OpenAccess #StatsTwitter #DataScience #MLtwitter

[TRIPODStatement @TRIPODStatement]

We've heard on the grapevine, there are still people who are not using the TRIPOD statement (😲we know) to report their prediction model study.

Enlighten them by pointing them to

https://t.co/ZoJLrj5izn (checklist)
https://t.co/TdtPbSksAw (explanation/examples)

#statstwitter

[Ewoud Schuit @ewoudschuit]

Roderick Venekamp, Lotty Hooft, Irene Veldhuijzen, Wouter vd Bijllaardt @SuzanPas Vivian Zwart @EstherLodder Marloes Hellwich, Marco Koppelman @Rimo42 Constantijn Wijers, Irene Vroom, Leonard Smeets @La_Nagel Wanda Han, Jan Kluytmans, Susan vd Hof, Janneke vd Wijgert @CarlMoons

[The BMJ @bmj_latest]

The performance of some home testing kits for covid-19 appears to have declined as the omicron variant emerged, suggests study based on three widely used rapid antigen tests. Performance improved when tests used both nose and throat samples
https://t.co/u3gDvWpDAS @carlmoons

[Carl Moons @CarlMoons]

If one is interested in the accuracy of Covid-19 self tests - when used at home (a real world validatie study) - you may want to read this paper. A comprehensive self test validation study, also investigating the added value of throat to nose sampling.

[The BMJ @bmj_latest]

The performance of some home testing kits for covid-19 appears to have declined as the omicron variant emerged, suggests study based on three widely used rapid antigen tests. Performance improved when tests used both nose and throat samples
https://t.co/u3gDvWpDAS @carlmoons

[Carl Moons @CarlMoons]

A unique endeavour this has been. My great Thanks to everyone across the globe, who contributed their data and/or expertise to this challenging but hugely important project that we started already in 2020! You all did it!

[Maarten van Smeden @MaartenvSmeden]

NEW PAPER
Large external validation of covid-19 prediction models for mortality @bmj_latest
TL;DR: performance highly heterogenous -- often pretty bad --, but some positive exceptions too that require some recalibration
https://t.co/iYThZtXpFj

[Maarten van Smeden @MaartenvSmeden]

NEW PAPER
Large external validation of covid-19 prediction models for mortality @bmj_latest
TL;DR: performance highly heterogenous -- often pretty bad --, but some positive exceptions too that require some recalibration
https://t.co/iYThZtXpFj

[Nico Gagelmann @NicoGagelmann]

@pauladhiman @GSCollins @DrGSBullock @Richard_D_Riley @BenVanCalster @CarlMoons @BenjaminSpeich @CSMOxford @BotnarOxford @ndorms Great article! Congrats!

[Carl Moons @CarlMoons]

@CMc_PhD @pauladhiman @GSCollins @DrGSBullock @Richard_D_Riley @BenVanCalster @BenjaminSpeich @CSMOxford @BotnarOxford @ndorms @AI_Sian97 Yes, the first domain (participants) but also the second (predictors) and third domain (outcome) includes signalling questions that address differences in data collection, in/exclusion, predictor measurements and outcome assessments between participants.

[Maarten van Smeden @MaartenvSmeden]

@pauladhiman @GSCollins @DrGSBullock @Richard_D_Riley @BenVanCalster @CarlMoons @BenjaminSpeich @CSMOxford @BotnarOxford @ndorms Great work Paula! Adding the link here for easy access: https://t.co/fmlB6gHPHH