Christopher Esk

Assistant professor, Uni Innsbruck; Research associate, Knoblich lab, IMBA

[The Knoblich Lab @Knoblich_lab]

Excited to share our latest preprint (@biorxivpreprint) on brain organoid development. Lead by Julia Naas and Meritxell Balmaña (@txellbalmana) with Arndt von Haeseler, Christopher Esk (@christopher_esk) and colleagues across Vienna. @MaxPerutzLabs, @IMBA_Vienna, @CeMM_News.

[Veronica Krenn @krenn_veronica]

Excited to share this work now published @naturemethods and to have contributed to develop this interesting model of cortical patterning. A fantastic collaborative work with another @Knoblich_Lab alumnus @BosoneCamilla , @castaldi_davide @CarloEmanueleV1 @humantechnopole

[Christopher Esk @christopher_esk]

Wohoo! Great work, @FahrenbergerM , on improving scRNA-seq analyses. Easy to use, implementation in Seurat workflow, better results across the board! Happy to have pitched in. Congratulations!

[Martin Fahrenberger @FahrenbergerM]

I m happy to present our latest preprint, and the main work of my PhD-project:
"GTestimate: Improving relative gene expression estimation in scRNA-seq using the Good-Turing estimator"
In this manuscript we introduce a new normalization method for scRNA-seq data.

[Martin Fahrenberger @FahrenbergerM]

I m happy to present our latest preprint, and the main work of my PhD-project:
"GTestimate: Improving relative gene expression estimation in scRNA-seq using the Good-Turing estimator"
In this manuscript we introduce a new normalization method for scRNA-seq data.

[Dominik Lindenhofer @DLindenhofer]

Very pleased to share our recent preprint for a targeted scDNA-scRNA-seq method. Thx a lot to everyone who contributed!

https://t.co/sSBn3R6saz

[Nature Cell Biology @NatureCellBio]

💫Two new papers and a joint News & Views article:
@Knoblich_lab & co perform whole-tissue #LineageTracing in human #CerebralOrganoids to reveal that a subpopulation of symmetrically dividing cells can adjust its lineage size depending on tissue demands.
https://t.co/RsABGzrRSm

[The Knoblich Lab @Knoblich_lab]

📢 We’re excited to share another story published this week in @NatureCellBio! An effort led by @DLindenhofer, Simon Haendeler, @christopher_esk & @jamielittleboy1.

Cerebral organoids display dynamic clonal growth and tunable tissue replenishment
(https://t.co/xJNLOJspxN)

🧵1/9

[IMBA imbavienna.bsky.social @IMBA_Vienna]

New paper alert! Jürgen Knoblich and his team describe how so many more neurons are generated in the human brain than in the brains of other animals. Now out at Nature Cell Biology. Find out more: https://t.co/qB8CUZHIWZ

[The Knoblich Lab @Knoblich_lab]

📢 Paper alert! Here's our latest @CellStemCell story, led by @catarinacsmc.

The corpus callosum safeguards interhemispheric communication in the human brain.
𝘈𝘙𝘐𝘋1𝘉 mutations cause agenesis/absence of the CC.
But by which mechanisms? ⤵
https://t.co/fmZbFCbLjo

🧵1/10

[The Knoblich Lab @Knoblich_lab]

We are excited to share our latest work on developing a model of the human dopaminergic system with functional dopaminergic innervation, which we use to study Parkinson’s cell therapy as well as the reward system, published today in Nature Methods (https://t.co/2Xf6JyG3K2).

[Christopher Esk @christopher_esk]

Cell biologist, author and fantastic mentor! Now I just need to work on my poem writing. Thanks for the great interview!

[nature @Nature]

Frances Brodsky is a cell biologist at University College London. She is also the author of three mystery novels set in the world of bench science https://t.co/UuJ09thWzM

[Nadine Ortner @OrtnerNadine]

So excited to finally share our work on one of the two first construct-valid mouse models of gating-modifying CACNA1D (Cav1.3) variants implicated in neurodevelopmental and endocrine dysfunction in @JCI_insight. https://t.co/SGXpLAj58d

[Christopher Esk @christopher_esk]

Thank you for the great meeting where this idea was crafted: Study Group Molecular Neurobiology of the @GBM_eV. And Biological Chemistry @degruyter_pub.

[Christopher Esk @christopher_esk]

Interested in genetic screening in human brain models? Check out our review. Great collaboration with @StemCellUibk.

https://t.co/JFZJbr9XQp

[Christopher Esk @christopher_esk]

Congratulations to @ChongLi_cl and everyone in @Knoblich_lab and @TreutleinLab
on this very cool project finally being published alongside https://t.co/yx1VeZ8bIF. I am very happy to have pitched in a little bit.

[The Knoblich Lab @Knoblich_lab]

We are thrilled to share our latest work, a collaborative effort with @TreutleinLab, in Nature (https://t.co/pChgPCFEOM). We introduce CHOOSE, a powerful screening system within cerebral organoids, through which we identified developmental defects associated with autism.
🧵1/7

[Francesca Finotello @Francesca_Fin_]

📢 Our review on next-generation #deconvolution of the tumor microenvironment has been published on @IRCellMolecBio! 🎉 https://t.co/9eOm2YGuU7

Kudos to @lorenzo_merotto @mzopog and @ConstantinZackl!

@DiSC_uibk @uniinnsbruck

[The Knoblich Lab @Knoblich_lab]

📣 Preprint alert!
Check out our latest story, led by @catarinacsmc.

The corpus callosum safeguards interhemispheric communication in the human brain.

𝘈𝘙𝘐𝘋1𝘉 mutations cause agenesis/absence of the CC.
We wanted to know why. 🤓

🧵1/9
https://t.co/RwkEOBpf31

[Francesca Finotello @Francesca_Fin_]

📢#PhD and #PostDoc positions in my group at @uniinnsbruck @DiSC_uibk to computationally reconstruct cancer interactomes from NGS multiomics

@FWF_at project in collaboration with @LabiLab5 @villunger @_JoelRiley

https://t.co/DyDhGG2CLF
https://t.co/gwS0EGgCvf

Please RT! 🙏

[Christopher Esk @christopher_esk]

„Remove academic age limits on ERC grants” - Jetzt unterschreiben! https://t.co/KqdyriNaPq via @Change

[Angeliki Spathopoulou @ASpathopoulou]

I am very honored to receive the Early Stage Funding from the University of Innsbruck, a research funding meant to support small projects of young scientists! I am looking forward to a fruitful year full of exciting new data! #iPSCs #stemcells @StemCellUibk @uniinnsbruck