Leveraging intrinsic flexibility to engineer enhanced enzyme catalytic activity | Proceedings of the National Academy of Sciences https://t.co/GCXInhtSPb
Molecules of the Month - November | https://t.co/db73sLG7G5
Two oral SARS-CoV-2 antivirals to help tame Covid, a remarkably selective CDK7 kinase inhibitor (>4000x), and a recently approved once-daily MET inhibitor among this month's.
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Selvan et al.'s data suggest that an optimal rhGAA ERT would require both N-glycan and proteolytic processing to attain the most efficient enzyme for glycogen hydrolysis and treatment of Pompe disease
https://t.co/49G9KnQ4gf