Very happy to announce our recent study is now available in JAMA Network Open. We investigated potential causal relationships between maternal antihypertensive drug exposure during pregnancy and offspring outcomes using Mendelian randomization. (1/4)
https://t.co/1UFd7Nfxm0
of intrauterine drug exposure on neonatal outcomes and provide an additional source of evidence, which may be triangulated with observational analyses and RCTs to indicate outcomes of interest for trials and highlight areas for enhanced pharmacovigilance. (4/4)
Our paper is out in the #EuropeanJournalofNutrition! We found #adiposity may not be the only factor responsible for the associations between #UPFs and some upper-aerodigestive tract #cancers 🍔🍟🥤⤵️
https://t.co/V5HvKbpSnr
Very happy to see the work from my rotation year, investigating whether childhood maltreatment interacts with genetic susceptibility to cardiovascular disease in the @uk_biobank, published in @PLOSONE https://t.co/q7ks0OK81L (1/3)
'Weak and pleiotropy robust sex-stratified Mendelian randomization in the one sample and two sample settings' 🧵
Our work is published at Genetic Epidemiology @genepisociety https://t.co/PvuNC8FJgU 1/
@AlexTISYoung@IntJEpidemiol Thanks! Within the review we don’t make any comparison between methods, and signpost the reader to the full paper for the full details.
Very happy to announce the publication of my recent paper "How to estimate heritability: a guide for genetic epidemiologists" in @IntJEpidemiol, now available here 🥳https://t.co/JRA7q9OEnY
Thank you to to all of my fantastic collaborators @venexia @RosaCheesman @bristimtom @mendel_random @nm_davies for all of their support and hard work on this project!
Further, it enables comparison of their suitability for different research questions with respect to the underlying assumptions, biases and suitability of the data one may have.
Understanding these elements is important to correctly interpret results and weight evidence.
If you're interested in CVD drug targets, Mendelian randomization or aortic valve stenosis, come see poster PB1518! Would also love to chat with zebrafish or CRISPR people 🤗 #ASHG22
If you're interested in how weight loss alters gene expression to protect from colorectal cancer come see my poster at #ASHG! Poster PB1215 in the cancer posters session this afternoon
Breast tissue is particularly susceptible to exposures between menarche and first birth. If at #ASHG22 check my poster looking at the effects of body size during this life stage on breast cancer (PB3471) @mrc_ieu w/ @mendel_random@ammhughes@iTomRichardson @alexhavdahl et al.
If you're at #ASHG and interested in Mendelian randomization of maternal exposure on foetal outcomes come and see my work with @nm_davies @venexia@mendel_random@BurdenChristy @alexhavdahl poster PB3446 😁