Ximin Chi

Group leader in School of Life Science, Xiamen University.
Structural biology of membrane proteins.

[Ximin Chi @Ciemen7]

An enjoying collaboration with Renhong Yan and Zilong Wang! The asymmetric conformational change of NaS1 during transport cycles was revealed. Besides, the structure of ACA bound NaDC1 can facilitate allosteric regulatory molecules development of SLC13s.

https://t.co/P99QgmYSsA

[Ximin Chi @Ciemen7]

Our new paper is online now~We predicted and summarized the folds of human SLCs, at the same time solved a new-fold transport protein --- SLC44A1. https://t.co/LuRMxqXKLG

[Tamir Gonen @gonenlab]

A simple explanation to sample preparation in #cryoem #MicroED experiments

[Ximin Chi @Ciemen7]

The paper of KCC2 and KCC3 is here~~
Glad the paper is still alive after so many related structures published. Importantly, the first structure of chemical bound SLC12 family protein is reported here. The potential dimer modulator is charming~
https://t.co/pL212fuKC6

[Transporters and Solute carriers @solutecarriers]

Structural insights into the gating mechanism of human SLC26A9 mediated by its C-terminal sequence https://t.co/dCvcEwalae

[Druse Labs @druselabs1]

#crystallization

[Ximin Chi @Ciemen7]

What a fierce competition in the field!😂
Molecular basis for regulation of human potassium chloride cotransporters https://t.co/1CfXVepBQw

[Ximin Chi @Ciemen7]

Molecular basis for allosteric regulation of the type 2 ryanodine receptor channel gating by key modulators https://t.co/8V55lZkFKy

[Ximin Chi @Ciemen7]

Modulation of cardiac ryanodine receptor 2 by calmodulin https://t.co/CJZm3m3iXa

[Paolo Swuec @PS_cryoEM]

@Kaelberviridae Here it is! We carefully check clips and rings one by one to remove damaged or bent. Still we recover 80% of them. In 2 years none failed in column.

[Ximin Chi @Ciemen7]

Oh, no.

[Phyre2 @Phyre2server]

Dear all: Bad news. Despite 2k+ letters of support, 90k unique users per year and >7.5k citations, the BBSRC has rejected our application for funding. Future very uncertain. Thank you all for your support.

[Da-Neng Wang @danengw]

Congratulations to Yifan for his election to the American Academy of Arts and Sciences!

[Ximin Chi @Ciemen7]

Titan map. https://t.co/ICI4RS1OiD

[bioRxiv @biorxivpreprint]

Structure and autoregulation of a P4-ATPase lipid flippase https://t.co/qeULu84d3C #bioRxiv

[Ximin Chi @Ciemen7]

Remarkable. https://t.co/q8Mqkvzqfr

[Ximin Chi @Ciemen7]

May be the hope of many dying projects which have no crystal, and too small for cryo-EM.
https://t.co/pVnxVpb2Zp

[Ximin Chi @Ciemen7]

Here is my first paper. https://t.co/kIDbv5vswX

[Ximin Chi @Ciemen7]

@LanderLab @markherzik @Mengwooo How did you decide the defoucus range for data collection? It must be a hard balance between SNR and resolution.