Cleveland Clinic MD

News and insights for physicians and clinical professionals from @ClevelandClinic | Research, case studies and the latest advances in patient care.

[Cleveland Clinic MD @CleClinicMD]

A 59-year-old with a history of bipolar disorder, HIV, cocaine abuse complicated by non-ischemic dilated cardiomyopathy and seizure disorder was admitted from an outside hospital.

The patient presented with concerns for respiratory failure and concern for medication-induced liver injury.

On arrival, the patient decompensated with worsening shock and encephalopathy, which required mechanical ventilation.

More about the case: https://t.co/2YxYo2vKqC

[Cleveland Clinic MD @CleClinicMD]

A new LLM-based tool is helping identify contraindications to thrombolysis by analyzing patient records in real time.

This system can alert providers to red flags that may not surface during fast-paced clinical decisions.

See how artificial intelligence is being trained to support safer, faster stroke intervention: https://t.co/fsVvaa1r8Q

[Cleveland Clinic MD @CleClinicMD]

Minimally invasive adrenal surgery continues to evolve with techniques designed to reduce recovery time and improve precision.

The mini back scope approach offers a targeted pathway that avoids entering the abdominal cavity, which may lower risk and support faster healing: https://t.co/LVAele3Ktw https://t.co/LVAele3Ktw

[Cleveland Clinic MD @CleClinicMD]

A four-year-old patient with multiple diagnoses was brought to the pediatric otolaryngology clinic for severe congestion, mucus and oral aversion.

Learn more about the case, including a mysterious finding: https://t.co/ZgYTA6nimm

[Cleveland Clinic MD @CleClinicMD]

We have launched a national tumor board dedicated to DNA repair and telomere biology disorders.

Bringing together multidisciplinary experts, this initiative supports clinicians managing some of the most complex and rare cancer-related conditions.

See how this national tumor board is shaping a more collaborative approach to rare disease management: https://t.co/0C0DMkakSi

[Cleveland Clinic MD @CleClinicMD]

Sudden cardiac death in athletes is rare, but when it happens the impact is devastating for families, teams and communities.

Screening protocols, emergency action plans and rapid access to defibrillators can make the difference between tragedy and survival.

Learn how a comprehensive approach to athlete heart health is helping protect lives on and off the field: https://t.co/IcOb2o81WF

[Cleveland Clinic MD @CleClinicMD]

A 72-year-old man with a history of smoking presented with a diagnosis of Extramammary Paget disease of his oral mucosa.

The patient had been seen by a community-based oral and maxillofacial surgeon due to unexplained weight loss over one year, as well as tenderness of his oral mucosa when eating, drinking and toothbrushing over the previous two months.

More about the case: https://t.co/J8ILakeOUi

[Cleveland Clinic MD @CleClinicMD]

Obesity in older adults is often misunderstood and undertreated.

But the risks and the opportunities for intervention are real at every age.

Effective management goes beyond weight loss alone. It requires preserving muscle mass, supporting mobility and addressing the whole patient with thoughtful, individualized care: https://t.co/qpAXHzIWPB

[Cleveland Clinic MD @CleClinicMD]

Specialized care for patients with diabetes goes beyond glucose control. It requires coordinated support that addresses complications, risks and long term health.

A multidisciplinary approach helps identify issues earlier and connect patients with the right expertise at the right time.

See how integrated care models can improve outcomes and support patients at every stage of their journey: https://t.co/TfUo4C77wG

[Cleveland Clinic MD @CleClinicMD]

A 2-month-old presented after being born premature with life-threatening congenital heart defects. He is our youngest patient to undergo a rare procedure where surgeons reroute the arteries to establish healthy blood flow: https://t.co/lZmR7PThSA

[Cleveland Clinic MD @CleClinicMD]

Cognitive fluctuations are a key but underrecognized feature in Alzheimer’s disease.

New insights suggest these temporary lapses may reveal underlying neurobiological changes related to sleep disruption, inflammation and vascular function.

Explore how understanding fluctuations could refine both diagnosis and care: https://t.co/SdlgDKq4Og

[Cleveland Clinic MD @CleClinicMD]

An international trial found that tavapadon improves symptom control in Parkinson’s disease. It also showed effectiveness as a standalone treatment for newly diagnosed patients. The drug was generally well tolerated, supporting its use as both an initial and add-on therapy: https://t.co/JfLFxKVBJI

[Cleveland Clinic MD @CleClinicMD]

A 4-month-old female presented with high-grade unilateral vesicoureteral reflux and a history of recurrent febrile urinary tract infection. At the time, her VUR was managed with antibiotic prophylaxis, a preferred approach for younger, nontoilet-trained children or milder forms of VUR.

5 years later, she was finally a candidate for surgery: https://t.co/he62rrshTb

[Cleveland Clinic MD @CleClinicMD]

Researchers have discovered a gene that predisposes patients to osteosarcoma, the bone tumor with the worst prognosis in children and adolescents.

While past studies have explored pathogenic variants in approximately 100 cancer-predisposing genes, this is the first time that pathogenic signals were comprehensively investigated across genes in DNA repair pathways.

More about the findings: https://t.co/RlQ4Hhj6XN

[Cleveland Clinic MD @CleClinicMD]

Dual agonist incretin therapy is demonstrating superior outcomes compared to GLP-1 monotherapy in both weight reduction and glycemic control.

The data reinforces a more aggressive, mechanism-driven approach to metabolic disease management: https://t.co/OP4GEgY61f

[Cleveland Clinic MD @CleClinicMD]

A 45-year-old female who was diagnosed with juvenile myositis in the 1980s presented for further evaluation of inflammatory myositis.

She was referred to our Neuromuscular Medicine Clinic, where genetic testing corroborated a rare diagnosis.

More about the case: https://t.co/ff0wqVSkgP

[Cleveland Clinic MD @CleClinicMD]

Endonasal skull base surgery is minimally invasive, but VTE risk still matters. Assumptions about low risk may miss key patient factors.

Risk is not just about the procedure. It is about the patient, timing and perioperative decisions.

See how evolving evidence is refining prevention strategies and shaping smarter care: https://t.co/n3Bcmk1e8s

[Cleveland Clinic MD @CleClinicMD]

AI is reshaping diabetic retinopathy detection. Fundus cameras can now identify disease earlier and more efficiently.

This shift brings screening closer to patients and helps prevent avoidable vision loss.

More about the technology: https://t.co/o5xVWXOqwQ

[Cleveland Clinic MD @CleClinicMD]

A new case report highlights what may be the first documented hypertensive emergency resulting from a combination of medications and psilocybin mushrooms.

The patient was a 42-year-old man with treatment-resistant major depressive disorder who developed severe hypertension and chest pain shortly after ingesting 1 gram of Psilocybe cubensis mushrooms.

More about the case: https://t.co/X2YlIgPORK

[Cleveland Clinic MD @CleClinicMD]

Cancer treatment can affect more than physical health. For many men, it can also have a lasting impact on sexual health and quality of life.

While these challenges are common, conversations about them are often avoided. The right support and treatment can help men address concerns and regain confidence after cancer: https://t.co/CKtEnBUR0i