Constance 😷🍁

[nature @Nature]

An antiviral pill has, for the first time, been shown to prevent COVID-19 in people exposed to the SARS-CoV-2 virus

https://t.co/OgfUZ00Hd4

[charlos @loscharlos]

If you see someone wearing a mask and your reaction is "why are they still doing that?" — It's because they're following the science, and you're not.

You're following a social norm created by the corporate takeover of public health, and they're not.

No need to further wonder!

[Dr. Lucky Tran @luckytran]

“We are told by leaders that we are the future. But when it comes to the ongoing pandemic, our present is being stolen right in front of our eyes.”

Incredible speech by Violet Affleck who warned about COVID & Long Covid, & advocated for masks & clean air at the UN today!

[AJ Leonardi, MBBS, MPH, PhD @fitterhappierAJ]

NIH RECOVER has found that incidence of long covid for infections in 2023 and 2024 has not been decreasing since 2021 and in fact, may steadily be increasing!

https://t.co/Af1w4CuQbp

This is despite assurances from Zeynep that 'novelty was severity' and Dr. Akiko Iwasaki saying:

"immunologically it's unlikely that you're going to develop long covid after a second or third infection because you've already developed some levels of immune responses"
https://t.co/FHSzthNGLT

"Top notch" analysis from experts like Zeynep claims, means nothing if they cannot use that information to understand and predict.

This is a failed analysis because immune responses do not equate to competent and effectual immunity, something that I have been shouting to individuals that seek to merely enumerate T cell reactivity following infection.

I was accused of lacking nuance and alarmism for claiming
1) covid harms the t cell arm of immunity
and
2) covid was intrinsically severe and I expected immune responses to decay with time

It seems as though others lacked nuance in their assessments. Also, doesn't the increasing trend of long covid incidence suggest there could be an effect from immune harm or growing immune incompetence?

Trust me, I am aware of the seniority of the individuals that I am calling out. Do you know how many times these people, despite being way off the mark, have used their positions as data collectors to assuage the public, have been awarded and courted by the National Academies of Science? The award is for saying the politically palatable thing.

https://t.co/Af1w4CuQbp

[@Riemerville @Riemerville]

A dear friend of mine, very careful about Covid, just caught it for the first time. I suggested rest, electrolytes, H1 & H2 blockers, zinc, and Paxlovid or metformin. What else would you suggest?

[charlos @loscharlos]

“A growing number of scientists believe the SARS-CoV-2 virus may be subtly altering our immune systems. If correct, their hypothesis will change how we understand everything from RSV to shingles to sepsis.”

“It’s certainly impacting our immune health & probably.. overall health”

[AJ Leonardi, MBBS, MPH, PhD @fitterhappierAJ]

Pretty much everyone ever infected has the signature of Covid embedded in their bodies, chronic T cell activation studies show.

Some people feel sick, and only a proportion link it to Covid.

[AJ Leonardi, MBBS, MPH, PhD @fitterhappierAJ]

Over a three year period, the risk of some cancer diagnoses doubled after SARS Cov 2 infection

Some will claim these people were susceptible to viruses anyway and thats why they had this outcome

Show me a person that isn’t susceptible to SARS COV 2 infection

I told you so

[Barry Hunt @BarryHunt008]

Good News!

Canadian Standards Association (CSA) has called for universal respirator use in healthcare settings & when performing patient care outside of healthcare settings (eg – in the home) in the latest edition of CSA Z94.4, Selection, use and care of filtering respirators.

[Dr. Sean Mullen @drseanmullen]

I keep seeing the question:
“Why is the government still acting like COVID isn’t airborne?”
Folks… where have you been?
They have admitted it. Quietly. Occasionally. Buried in a PDF.
But they don’t stress it.
They still lead with handwashing.
They still avoid requiring masks.
They say “ventilate” but don’t mandate clean air.
Because a full-throated acknowledgment would mean:
→ retrofitting schools and nursing homes
→ regulating indoor air across industries
→ protecting workers, kids, patients… by law
→ and worst of all (for them)...
It would mean liability.
Lawsuits. Settlements. Accountability.
And the buildings that need fixing?
They’re owned by politicians.
Their families. Their donors. Their friends.
So they’ll whisper the truth,
and shout the lie.
Because if they admitted it’s airborne their whole system would go up in aerosols. 💨

[PolyBio @polybioRF]

Dr. Amy Proal last week: “When people get an infection, there’s a huge assumption that it just clears after their symptoms go away… Little amounts of the pathogen [can persist] in parts of your tissue, parts of your nerves—where they can still drive inflammation and directly hijack the functioning of your mitochondria.”

[Dr. Sean Mullen @drseanmullen]

The good news is: COVID won’t kill you instantly anymore.
The bad news is: it’ll rot your insides while you smile through a team meeting …
a meeting about why you're suddenly breathless, confused, and forgetting names...
…symptoms that, pre-pandemic, meant cardiovascular disease and early-onset dementia.
But that can’t be right.
You're only 25.
Must be burnout. Or vibes. Or the weather.

[T. Ryan Gregory 🇨🇦 @TRyanGregory]

Meet "Nimbus", aka SARS-CoV-2 variant NB.1.8.1.

🧵

1/

[Dr. Sean Mullen @drseanmullen]

I don’t think people ‘get it’ when it comes to asymptomatic transmission.

We’ve known since early 2020 that people without symptoms—either because they haven’t developed them yet or never will—can still spread disease. But health systems around the world keep making the same mistake: they build their entire outbreak response around people who feel sick. This review calls that out.

The authors in this paper (link 👇) looked across 15 pathogens, from SARS-CoV-2 to malaria to polio, and found a messy, inconsistent landscape. Not only is there no standard language for what we mean by “asymptomatic,” but many public health strategies act like these folks don’t exist—despite being central drivers of outbreaks.

Key takeaways:
1.Asymptomatic ≠ Harmless. Across nearly all diseases studied, a significant chunk of transmission comes from people without symptoms. With COVID, that’s more than half of all spread. With polio? Up to 99%.
2.This isn’t just about COVID. We’ve seen this with TB, malaria, dengue, HIV, typhoid—and even hints with Ebola. The issue isn’t the virus or bacteria—it’s the blind spot in our response.
3.The vocabulary is a mess. We toss around terms like “asymptomatic,” “pre-symptomatic,” “subclinical,” or “carriers,” but public health programs rarely define these clearly, which leads to gaps in tracking and treatment.
4.Evolution favors stealth. Some pathogens evolve to fly under the radar—transmitting more before people even realize they’re sick. Think of it as a biological strategy: don’t knock the host off their feet too early.
5.We’re designing policies for the wrong targets. Testing, isolation, vaccination strategies—all tend to focus on visible symptoms. That approach might have worked for smallpox, but it fails when your biggest spreaders don’t cough, sneeze, or even feel off.
6.Surveillance is outdated. We’re not collecting the right data. And when we do, we’re often using tools and definitions that underestimate silent spread. The paper recommends updating both methodology and mindset.

Bottom line?
If we keep ignoring the silent majority of transmitters, we’re playing catch-up with every new outbreak. We need clearer terminology, better detection, and interventions that acknowledge that just because someone feels fine doesn’t mean they’re not infectious.

Source: https://t.co/0CpIwfZURi

[Dr. Pat Soon-Shiong @DrPatrick]

Loss of p53 is now being reported from multiple sources. Very concerning.

[The Yeti of Kananaskis @kananaskinyeti]

Covid killed the pope. And the queen. And Pele. It’s the reason Biden dropped out. It’s why your favourite artist is sick, stopped touring or has come down with serious health complications. It’s why the kids are failing at school, it’s why the schools are failing. It’s all Covid

[Dr. Pat Soon-Shiong @DrPatrick]

https://t.co/WyGX2VdT8H

[Constance 😷🍁 @Constanc333]

@Ninawildflower Hi - I'd like to join please!

[Dr. Lucky Tran @luckytran]

Please ignore tired pieces in publications like the Atlantic that are still trying to stigmatize mask wearing.

Wearing a mask to prevent sickness from airborne viruses is a science-informed position, and it has been that way for over 100 years.

[AJ Leonardi, MBBS, MPH, PhD @fitterhappierAJ]

I wish Michael Mina and Zeynep Tufekci would have told us this "textbook virus" may cause cancer, like Dr. Patrick Soon-Shiong has said.