Co-Operative Studies on Brain Injury Depolarizations (COSBID) is a research interest group focused on cortical spreading depolarizations #TBI#stroke#SAH#ICH
When 100+ spreading depolarizations run through the temporal lobe of a brain injured human being, the question of treatment goes beyond academic musings. We need answers.
Today marks 75 years of spreading depression research! August 14, 1944, Leão's landmark paper was received for publication in @JNeurophysiol. It would take 58 years for Leão's work to be translated to the clinic, sparking a #SpreadingDepolarizations Renaissance! #TBI#stroke#SAH
Thanks to Drs. Suzuki and Oka for hosting another excellent COSBID meeting - the first in Asia - in Yokohama, Japan. Excellent discussions and science among a very thoughtful group. #spreadingdepolarizations
If you haven't already, please be sure to register for this year's #COSBID2019 in Yokohama, Japan!
https://t.co/bHEbttinHY or see https://t.co/33nmCGhJER for more information!
Very good visualizations of cortical spreading depolarizations #AANAM
Radial, spiral and reverberating waves of spreading depolarization occ... https://t.co/CCTaEDTKFm
The Continuum of #spreadingdepolarizations is the SECOND most cited reference @_JCBFM of the last three years! Congrats to the @JedHartings and co-authors!
https://t.co/iJmuqFhbwD
A case of amyloid angiopathy presenting with 15-20 min transient neuro symptoms (‘amyloid spells’) related to migraine-like #spreadingdepolarizations. Characteristic MRI and biopsy confirmed the diagnosis! @COSBID#AANAM
Looking forward to presenting our work from @UofR@URNeuroscience on the role of the #glymphatic system in driving cerebral edema after acute ischemic stroke tomorrow at #AANAM@AANMember. Stop by room 118A at 3:50pm!
Why isn't there a perfect animal model for aneurysmal subarachnoid hemorrhage? We wrote this article to try answering the question, and to start a conversation about what sorts of outcomes matter for translation to patients. https://t.co/DCQjU9v6hH https://t.co/vFO0NVEGX5
A technical guide to imaging cerebral blood flow in rodents @_JCBFM from David Kleinfeld's lab @UCSDNeuro@UCSDHealth@UCSDnews - Two-Photon Microscopy to Study Blood Flow and Neurovascular Coupling https://t.co/xPopn6xkJ3
Just ONE WEEK until our next #BrainMatters webinar! Join us on March 1st at 1pm EST to learn more about spreading depolarizations in the injured brain with Sharon Jewell.
Register here: https://t.co/U7GPczvUz1
Interesting study! Especially in light of recent work on cilostazol (also inihibits plt aggregation and promotes vasodilation via phosphodiesterase inhibiton). Wonder what the effects of terutroban are on #spreadingdepolarizations? #SAH
Thromboxane–prostaglandin receptor antagonist, terutroban, prevents neurovascular events after subarachnoid haemorrhage: a nanoSPECT study in rats
#FOAMcc
https://t.co/v0Xnkyq1et