CyanoGrowth

everything phototrophic growth: cyanobacteria, green biotech, metabolic network reconstruction, systems biology, microbial ecology, microbial evolution

[CyanoGrowth @CyanoGrowth]

New article "Resource allocation models: theory and applications in microbial biotechnology" with https://t.co/GX25pk24av: https://t.co/Ht4vPBCDmZ

[CyanoGrowth @CyanoGrowth]

here we go ...

[CyanoGrowth @CyanoGrowth]

New preprint on a kinetic model of cancer metabolism: https://t.co/rNCly0iWYJ (no cyanos this time).

[CyanoGrowth @CyanoGrowth]

New paper out today: https://t.co/7DX2YSByUA A collaboration with Almut Schulze, Matti Snaebjornsson and others from DKFZ on imbalanced glycolysis and energy stress due to uncontrolled FBP accumulation. Not cyanobacteria, but still good! Pdf: https://t.co/wz5NFzVHfT

[CyanoGrowth @CyanoGrowth]

EWBC 2024 is ready to go!

[CyanoGrowth @CyanoGrowth]

New review online "Design of microbial catalysts for two-stage processes", and thanks to all involved, in particular Kiyan, for the great work!
https://t.co/j8m7k3GCE4

[CyanoGrowth @CyanoGrowth]

We study an updated reconstruction of Synechocystis 6803 and show that light absorption, O2 evolution, O2 consumption, biomass yield, ATP/NADPH production, and growth rate taken together give rise to a quantitative and consistent overall picture of cyanobacterial energetics.

[CyanoGrowth @CyanoGrowth]

New article online now: A quantitative description of light-limited cyanobacterial growth using flux balance analysis #PLOSCompBio https://t.co/F1gWm3L1DQ

[CyanoGrowth @CyanoGrowth]

We have a new preprint on cyanobacterial metabolism!
Our approach, based on FBA, provides quantitative description of cyanobacterial growth, and accounts for a variable quantum yield and photodamage, thereby going beyond "conventional" FBA.
https://t.co/lRxcglepui

[CyanoGrowth @CyanoGrowth]

Today is another installment of our Forum on "Economic Principles of Cell Physiology" (EPCP). This time about "Divergent strategies of proteome allocation by fast- and slow-growing bacterial species" (Jan 9, 5:30pm, CET) on Zoom. Register: https://t.co/1t0hAJRxTh

[CyanoGrowth @CyanoGrowth]

off to "Mechanisms of Molecular Evolution" ...

[CyanoGrowth @CyanoGrowth]

New article! I am very happy about it, it contains quite a few interesting thoughts: Trade‐offs between the instantaneous growth rate and long‐term fitness: Consequences for microbial physiology and predictive computational models. https://t.co/fKQ10GNPT1

[CyanoGrowth @CyanoGrowth]

today is also another session on our forum on quantitative microbiology: https://t.co/1t0hAJRxTh 5:30pm CET!
#CellularEconomyForum

[CyanoGrowth @CyanoGrowth]

And one more paper on time-optimal adaptation in metabolic network models (this one is a bit more technical): https://t.co/RN319FkYbD

[CyanoGrowth @CyanoGrowth]

in brief: growth rate itself does not determine productivity. A fast growing strain might be like a sports car that goes fast by guzzling up fuel, not by being productive or efficient. We also need to look at further parameters to determine productivity (yield, efficiency).

[CyanoGrowth @CyanoGrowth]

still not the most proficient twitter user here, but we got a new paper on fast growing cyanos: Fast-growing phototrophic microorganisms and the productivity of phototrophic cultures. Biotechnology and Bioengineering, 119, 2261– 2267. https://t.co/sZeFif2abK

[CyanoGrowth @CyanoGrowth]

Our latest paper is online now: Modelling microbial communities using biochemical resource allocation analysis https://t.co/CiZ5HuEe8H

[CyanoGrowth @CyanoGrowth]

And to put the account to good use: Our latest paper "Optimal proteome allocation strategies for phototrophic growth in a light-limited chemostat" is now online: https://t.co/iFL6TYAgj3

[CyanoGrowth @CyanoGrowth]

"Hello World!" My first attempt at twitter. It will be a slow start ...