Dallinar

[Dallinar @Dallinar]

@Noortwyck @DrNadolsky Semaglutide intense dietary intervention group w/premade meals, biweekly meetings with dietitians and prescribed exercise regimens: 5.7% weight loss vs 16.0% with semaglutide https://t.co/HISWd4MRex

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@Noortwyck @DrNadolsky I���m saying on average in clinical trials participants in the lifestyle intervention group lose 5-7% body weight. If we call 10% clinically meaningful then maybe 25-33% achieve clinically meaningful body weight reduction, as opposed to 75%+ in the medication groups

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@Noortwyck @DrNadolsky “Small percentage” in clinical trials very intensive lifestyle intervention produces 5-7% weight reduction. The majority of patients in those clinical trials fail to produce meaningful weight reduction and that’s with the best lifestyle interventions possible

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@kevinnbass How do you survive without navigation though?

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@fan_bedford @realbedford Seems like a normal price to me?

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@NonsenseKiller7 @rashmeeushah @AnnMarieNavar @ericpetersonMD Read the first paper I linked from the European Atherosclerosis Society. It argues (successfully in my mind) that ldl has been proven to be causal

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@rashmeeushah @AnnMarieNavar @ericpetersonMD 1. LDL is linearly causal in ASCVD https://t.co/hhfDjR6TOL
2. Atherosclerosis is a decades long process
3. Lifetime risk of ASCVD in females is 39%
4. Lipid lowering therapies are extremely safe and effective even in completely healthy individuals https://t.co/yr2dMvDR0R

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@MichaelAlbertMD Sarcasm?

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@DigiEconomist @gladstein The energy companies make more money and are thus able to build out more grid capacity because they have demand from miners that wouldn’t otherwise be there

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@JLVelasquezP11 @DrNadolsky Please explain how a doctor makes money from prescribing a medication. Perhaps you’re unaware that we do not get paid for prescriptions

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@Drlipid Especially when combo meds exist that allows patient to still only take one pill, why not add ezetimibe to most all statin regimens

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@kevinnbass Irrespective of reduce-it an effect was seen in RCTs for CVD https://t.co/McLcQduaN0

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@FormulaUR_ Yes! Honestly don’t see this type of content anywhere else, keep it up

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@m_franceschetti @scanlinjoe @eightsleep Will the new sensors be essential for new features in the foreseeable future? Or just make things more accurate?

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@JuliaB_fitness @Marc_Veld I feel like good data is really lacking in this area though, are there studies showing efficacy? And putting to rest safety concerns of high dosages?

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@kevinnbass The combination ace/arb + amlodipine pills are great

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@JPSwcpmc Or a combo pill! Almost no downside

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@kevinnbass Btw you were totally right on how good the Premier Proteins are, been chugging those things on a regular basis

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@kevinnbass Be well!

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@kevinnbass This includes SPRINT. Perhaps paradoxically it seems logical to preventatively treat aggressively in younger people when fall risk is zero and be more conservative at older age. Not sure if any explicit data exist but logically it makes sense from the existing data

[Dallinar @Dallinar]

@kevinnbass The data on all-cause mortality seems less certain from this meta-analysis showing essentially no difference, especially in lower BP groups