Dan Carbin

Works on health policy and strategy. Thinks about lots of other stuff. Still believes it is possible to disagree with you and like you as a person.

[Dan Carbin @DanCarbin]

It is shocking to me that someone could have a single great great great grandparent who was Canadian and have right to get CDN citizenship for them and their kids at any time. That is a pretty low bar. https://t.co/nXdosojGfu

[Dan Carbin @DanCarbin]

Honest question: Has "Communist China" ever filed an FOI request to get any government record in Ontario? Don't they just hack into our IT systems and take what they want? https://t.co/5t0QCHlTsQ

[Dan Carbin @DanCarbin]

If this kind of change keeps up it will require significant changes to the regulatory and funding process for drugs in all countries. We are going to see a wave of new innovation.

[Mgoes (bio/acc 🤖���) @m_goes_distance]

It's genuinely insane how much progress biotech has made in the last 90 days:

- Two years ago I watched Lucy Therapeutics shut down after 7 years and $42M from Bill Gates, never reached human trials. Last month DeSci crowdfunded €2.5M in 72 hours for Dr Barbacid cancer trials and went straight to human trials. Zero VCs and zero committees in the middle. And it's not even about the money. The goodwill

- Gene therapy cost $2-4M per treatment a year ago because manufacturing was artisanal and nobody was actually solving it. Now automation's dropping costs toward $200. Turns out it was an engineering problem all along.

- Just a year ago, the FDA wouldn't touch longevity.
In January 2026, first FDA-approved human trial reversing cellular age launched (ER-100). We're testing age reversal in humans right now. Not mice.

- Psychedelics stuck in regulatory hell for 50 years.
In February 2026, Compass crushed Phase III for psilocybin in treatment-resistant depression.

- In 2023, AI drug discovery was hype. $17B got invested, zero approved drugs.
Early 2026, Ginkgo x OpenAI ran over 200k autonomous experiments, 36K of those were unique. Protein costs dropped by 40% and they're already shipping commercially. Discovery timelines collapsed.

- Just last year, FDA required full GMP pre-Phase 2, moved at 1950s speed. This quarter,we're fast-tracking frontier therapies, relaxing requirements, launching pilots. Something shifted and the regulatory wall is cracking.

- In 2024, clinical trials had to run in US at 2x cost, half the speed. Right now in Singapore and China running trials 50% cheaper, 2x faster. Companies routing around FDA entirely. The US model is optional.

I could keep going on with these, but you realize that the bottleneck was never the science. It was funding models, regulatory speed, manufacturing, geography etc

And most of them are breaking since last October.

Biotech has shed 30 years of broken infrastructure in 5 months and I can't be more bullish.

bio/acc.

[Dan Carbin @DanCarbin]

I worked for a Premier & 2 Cabinet Ministers. Having your correspondence subject to FOI is a PITA, but it is the price of serving the public in a democracy. This move is profoundly bad public policy. By making it retroactive, it reeks of cover-up. https://t.co/tigAyBg45J

[Dan Carbin @DanCarbin]

The rigidity in Canadian thinking about this kind of thing is so disappointing as a citizen & taxpayer. I would much prefer that the costs of hosting a commercial event (the World Cup) be covered by corporate sponsors as opposed to tax payers. https://t.co/sDpY3gP8Dy

[Dan Carbin @DanCarbin]

Opinion: How must the world stand up to Donald Trump? /via @globeandmail https://t.co/EKEaPX1YXA: Social Network / Media

[Dan Carbin @DanCarbin]

@mikepompeo In this case, I think potash would be more appropriate than pottage, but really what choice does the guy have given your imperialist bullying?

[Dan Carbin @DanCarbin]

It is so sad that this kind of exercise is now so necessary - https://t.co/KpLQ5peFu1

[Dan Carbin @DanCarbin]

It was pretty clear at the time that this was a depressing lurch towards authoritarianism in Canada. It just happened to come from the left and thus didn’t align with the dominant narrative of the moment, allowing Trudeau to mostly get a way with it. https://t.co/48Qmt5vl7h

[Dan Carbin @DanCarbin]

The choice may be boring, but these “critics” need to find a real problem to tackle / bloviate about. Just absurd. https://t.co/fNSrtsQG18

[Dan Carbin @DanCarbin]

Well, this certainly sounds like a boondoggle #onpoli - “Brampton-based Scooty Mobility, which rents e-scooters, was given $1 million to teach 100 workers about the “transformative impact of AI in fintech” https://t.co/8OXbkE7EsX

[MeidasTouch @MeidasTouch]

Here’s the original clip of Ronald Reagan from April 25, 1987, where he delivered a complete and total rebuke against tariffs. Trump is calling Reagan’s words in this video “FAKE” and “fraudulent.” They’re 100% real. And the original clip is actually far worse for Trump, as much is left out of the ad. Watch this clip and read the full transcript:

Throughout the world, there's a growing realization that the way to prosperity for all nations is rejecting protectionist legislation and promoting fair and free competition. Now, there are sound historical reasons for this. For those of us who lived through the Great Depression, the memory of the suffering it caused is deep and searing. And today, many economic analysts and historians argue that high tariff legislation passed back in that period, called the Smoot-Hawley tariff, greatly deepened the depression and prevented economic recovery.

You see, at first when someone says, let's impose tariffs on foreign imports, it looks like they're doing the patriotic thing by protecting American products and jobs. And sometimes for a short while, it works, but only for a short time. What eventually occurs is, first, homegrown industries start relying on government protection in the form of high tariffs. They stop competing and stop making the innovative management and technological changes they need to succeed in world markets.

And then, while all this is going on, something even worse occurs. High tariffs inevitably lead to retaliation by foreign countries and the triggering of fierce trade wars. The result is more and more tariffs, higher and higher trade barriers, and less and less competition. So soon, because of the prices made artificially high by tariffs that subsidize inefficiency and poor management, people stop buying.

Then the worst happens. Markets shrink and collapse, businesses and industry shut down, and millions of people lose their jobs. The memory of all this occurring back in the 30s made me determined when I came to Washington to spare the American people the protectionist legislation that destroys prosperity. Now, it hasn't always been easy. There are those in the Congress, just as there were back in the 30s, who want to go for the quick political advantage, who risk America's prosperity for the sake of a short-term appeal to some special interest group, who forget that more than 5 million American jobs are directly tied to the foreign export business, and additional millions are tied to imports.

Well, I've never forgotten those jobs. And on trade issues, by and large, we've done well.

[Dan Carbin @DanCarbin]

@fordnation Run this ad more. Run it everywhere. https://t.co/6nzT9DW4S6

[Dan Carbin @DanCarbin]

How hilariously inappropriate that the picture accompanying this article including the “it’s happening!” tagline by Metrolinx. So much public faith has been lost in this botched transit fiasco. https://t.co/JZC9qetD4V

[Dan Carbin @DanCarbin]

RIP Jim Bradley. This is a touching tribute by @spaikin. I learned a ton just watching Bradley in action at the Cabinet table. He understood his community so well, which is why he just kept winning and winning in a tough riding. https://t.co/cSEQKmozo8

[Dan Carbin @DanCarbin]

I think we need to start planning for a world where there is no longer a government owned and delivered postal service. That is obviously the final destination. https://t.co/XWsJRvZP27

[Dan Carbin @DanCarbin]

I agree. MAGA is now the clear present danger to freedom of expression, but both parties in the US have been too far keen to cancel and shut down dissenting voices when what we need is a diversity (or even cacophony) of competing perspectives to keep democracy healthy.

[Barack Obama @BarackObama]

After years of complaining about cancel culture, the current administration has taken it to a new and dangerous level by routinely threatening regulatory action against media companies unless they muzzle or fire reporters and commentators it doesn’t like. https://t.co/uts7JpJZzN