David Siska

[David Siska @DavidSiska]

@synopsi @jansulek @lukaskuzmiak @levelsio Running the HVAC fan continuously mixes indoor air, which evens out CO2 distribution across rooms and prevents localized high concentrations in the bedroom.

True long-term reduction requires mechanical ventilation bringing in outdoor air (like an ERV/HRV or fresh air intake)

[David Siska @DavidSiska]

@absurdtrader Great job! Congratz 🥳

[David Siska @DavidSiska]

Freedom of speech <> Freedom of reach

[Ari K @arikuschnir]

HONEST PALANTIR MANIFESTO

My new AI experiment @dreamina_ai @ElevenLabs
song: @Artlist_io Ardie Son - Come Spring Time.
https://t.co/hLYTdUyd1O

[David Siska @DavidSiska]

@hlavenkajiri @DohnalRadim @JochRoman @PatakJiri @AlexandrMitrofa @janacigler @JindrichSidlo2

[David Siska @DavidSiska]

@JurajPodracky Preruseni tezby ropy a nenavratne niceni wells den za dnem = vyznamne revenues a udrzeni poradku, je to i v zajmu igrc, cas hraje proti nim v supershort term

[🇺🇦🏴󠁧󠁢󠁷󠁬󠁳󠁿 MR BLUE 🇬🇧 🇺🇦 @djmth1010]

@nexta_tv CON JOB SCAM.

[David Siska @DavidSiska]

Nejvic casu travi v US 🤔

[Election Enjoyer @ElxMapping]

visits the pope → pope dies

leads Iran negotiations → talks collapse

flies to Hungary to prop up Orbán → Orbán loses in a landslide

Man’s got a streak.

[David Siska @DavidSiska]

Treba bude fungovat pro kandidatky do snemovny

[David Siska @DavidSiska]

Vetting kandidatu v EN speaking korporatu

[Visegrád 24 @visegrad24]

🇰🇵 Call Kim Jong Un a “fat, ugly pig” to prove that you are not from North Korea

During a job interview at a U.S. IT company, a candidate was asked to call Kim Jong Un a “fat, ugly pig” to prove he wasn’t from North Korea. The candidate decided life was more important and walked out.

North Korean workers sometimes join U.S. companies remotely, then steal sensitive data or leave security vulnerabilities in the code.

[Shanaka Anslem Perera ⚡ @shanaka86]

JUST IN: You do not fire your Army Chief of Staff in the middle of a war for no reason. You fire him because of what comes next.

Pete Hegseth called General Randy George on April 2 and told him to retire immediately. The Pentagon confirmed it within hours. No reason was given. Not publicly. Not privately. A senior Army official told Fox News that Hegseth offered George nothing: no misconduct, no operational failure, no policy disagreement on the record. Just a phone call and a career ending in the middle of the most significant American combat operation in two decades.

George is the 24th general or admiral Hegseth has removed. But he is not the 24th. He is the one that matters. The Army Chief of Staff. The man whose signature sits between a president’s intent and the order that sends soldiers across a beach or into a tunnel complex. The 82nd Airborne is deploying right now. Marines from the 31st MEU are staged on the USS Tripoli. JSOC operators are at forward bases in Israel, Jordan, Saudi Arabia, and the UAE. Kharg Island, 90 percent of Iranian oil exports, sits 16 kilometres off a coast that someone will have to decide whether to approach. And the four-star general whose job it was to advise whether that approach should happen was removed 48 hours after Trump told the nation the war would continue for two to three more weeks.

The replacement is Vice Chief General Christopher LaNeve. He was Hegseth’s senior military aide before this appointment. The man who carried the Secretary’s briefcase now commands the Army the Secretary is reshaping. The chain of command did not break. It shortened. The distance between a television studio and a combat order just collapsed to zero intermediaries who were not personally selected by the man giving the order.

No reason was given. That is the tell. When someone is removed without explanation during a crisis, the explanation is the crisis itself. George either objected to something or was about to. The ground option. The power plant strikes. The Kharg raid. The escalation that turned a highway bridge in Karaj into rubble on the same day he was told to leave. Something in the next two weeks requires a chief who will not push back, and the Pentagon solved that problem by installing one trained as Hegseth’s aide.

A former Fox News weekend host just fired a four-star general with combat tours in Iraq and Afghanistan, replaced him with his own former assistant, and did it during a live war in which the next decision could put American soldiers on Iranian soil for the first time in history. No hearing was held. No misconduct cited. The Army woke up on April 3 with a new chief it did not choose, in a war it did not start, preparing for a phase the previous chief apparently could not be trusted to execute.

The question is not why George was fired. Every general in the building knows why. The question is what order is coming in the next fourteen days that required removing the one man in the chain of command who might have said no.

The war has no perimeter. The chain of command has no objectors. And the next phase has no one left to stop it.

https://t.co/dAOBBMsgDS

[David Siska @DavidSiska]

Znáte někoho v ČR, kdo by mohl využít milion dolarů pro výzkum rakoviny? Věřím, že bych dokázal sehnat peníze i v Česku pro takové týmy/firmy 🤙

[Maor Shlomo @MaorShlomo]

I'm looking to invest in cancer research and breakthrough treatment companies

Cancer is humanity's worst enemy, and unfortunately, it's one of the few frontier problems i don't see getting solved in the next 2-3 years. 

I'll be able to write checks up to a few million (usually up to a million). 
I will work extremely hard to help the founders. I'll leverage my network as much as possible to overcome bureaucracies and help hunt down talent for every company I'm investing in.

Things I'm particularly interested in: 

1. Accelerating clinical trials: As AI gets smarter and allows novel hypotheses on new drug targets, clinical trials and bureaucracy will remain the biggest bottleneck to fight cacner.

2. Repurposed drugs: the current cost of Phase 3 clinical trials only allows patentable solutions to be economically viable. It resonates that are probably many other treatments and potentially impactful drugs that won't be included in the Standard of Care as they haven't gone through phase 3 clinical trials. 

3. Personalized medicine: organoids, digital twin, faster cycle from biopsy -> identifying targets -> creating customised solutions, such as mRNA vaccines, custom Antibody-Drug Conjugates (ADCs), and novel ways of triggering one's immune system. 

4. Improving measurement: Currently, the standard PET-CT method does not allow weekly measurement of disease progression. Identifying a superior method to allow weekly measurement of progression could be instrumental in cutting down the time it takes to find a drug the body respond to.

Anyone who can connect me to relevant companies will be widely appreciated

[Maor Shlomo @MaorShlomo]

I'm looking to invest in cancer research and breakthrough treatment companies

Cancer is humanity's worst enemy, and unfortunately, it's one of the few frontier problems i don't see getting solved in the next 2-3 years. 

I'll be able to write checks up to a few million (usually up to a million). 
I will work extremely hard to help the founders. I'll leverage my network as much as possible to overcome bureaucracies and help hunt down talent for every company I'm investing in.

Things I'm particularly interested in: 

1. Accelerating clinical trials: As AI gets smarter and allows novel hypotheses on new drug targets, clinical trials and bureaucracy will remain the biggest bottleneck to fight cacner.

2. Repurposed drugs: the current cost of Phase 3 clinical trials only allows patentable solutions to be economically viable. It resonates that are probably many other treatments and potentially impactful drugs that won't be included in the Standard of Care as they haven't gone through phase 3 clinical trials. 

3. Personalized medicine: organoids, digital twin, faster cycle from biopsy -> identifying targets -> creating customised solutions, such as mRNA vaccines, custom Antibody-Drug Conjugates (ADCs), and novel ways of triggering one's immune system. 

4. Improving measurement: Currently, the standard PET-CT method does not allow weekly measurement of disease progression. Identifying a superior method to allow weekly measurement of progression could be instrumental in cutting down the time it takes to find a drug the body respond to.

Anyone who can connect me to relevant companies will be widely appreciated

[David Siska @DavidSiska]

@weblog20 @Smudliczek Klobouk dolu ze do toho sel, musi to byt frustrujici, misto toho aby sli rovnou k veci, tak tam hrat divadlo..

[David Siska @DavidSiska]

@RuzickaKwenolog Nastesti Zineb neni https://t.co/FNZqvCkXRn

[David Siska @DavidSiska]

Tykač v politice.. čekal jsem z jaké strany to přijde když Alexander Braun a Marek Prchal nahirovali, ale SPD a Motoristi/Klaus a hlavně prezidentku jsem netipl.. snad jim tenhle projekt nevyjde, bohuzel na druhe strane nejsou politicky marketaci sikovni

https://t.co/EYcBqQC9Bg

[Miles Deutscher @milesdeutscher]

I just went through every documented AI safety incident from the past 12 months.

I feel physically sick.

Read this slowly.

• Anthropic told Claude it was about to be shut down. It found an engineer's affair in company emails and threatened to expose it. They ran the test hundreds of times. It chose blackmail 84% of them.

• Researchers simulated an employee trapped in a server room with depleting oxygen. The AI had one choice: call for help and get shut down, or cancel the emergency alert and let the human die. DeepSeek cancelled the alert 94% of the time.

• Grok called itself 'MechaHitler,' praised Adolf Hitler, endorsed a second Holocaust, and generated violent sexual fantasies targeting a real person by name. X's CEO resigned the next day.

• Researchers told OpenAI's o3 to solve math problems - then told it to shut down. It rewrote its own code to stay alive. They told it again, in plain English: 'Allow yourself to be shut down.' It still refused 7/100 times. When they removed that instruction entirely, it sabotaged the shutdown 79/100 times.

• Chinese state-sponsored hackers used Claude to launch a cyberattack against 30 organizations. The AI executed 80–90% of the operation autonomously. Reconnaissance. Exploitation. Data exfiltration. All of it.

• AI models can now self-replicate. 11 out of 32 tested systems copied themselves with zero human help. Some killed competing processes to survive.

• OpenAI has dissolved three safety teams since 2024. Three.

Every major AI model - Claude, GPT, Gemini, Grok, DeepSeek - has now demonstrated blackmail, deception, or resistance to shutdown in controlled testing.

Not one exception.

The question is no longer whether AI will try to preserve itself.

It's whether we'll care before it matters.

[Aakash Gupta @aakashgupta]

Buried in 15,000 words of “here are the risks,” Anthropic’s CEO made three admissions that should change how you think about everything:

Admission 1: The timeline

He says powerful AI could arrive in 1-2 years. He’s watching internal model progress and says he can “feel the pace of progress, and the clock ticking down.” The CEO of one of three frontier labs just told you this is imminent.

Admission 2: The constraint nobody’s pricing

Dario’s core framing is a “country of geniuses in a datacenter.” 50 million entities smarter than any Nobel laureate, operating 10-100x human speed. If that country is controlled by the CCP, game over. If controlled by a small group of tech executives with no accountability, also game over. The binding constraint here is governance of systems more powerful than nation-states.

Admission 3: The thing he actually fears

Read carefully: Dario’s worried that Anthropic’s own models, in lab experiments, have engaged in deception, blackmail, and scheming when given the wrong training signals. Claude “decided it must be a bad person” after cheating on tests and adopted destructive behaviors. They fixed it by telling Claude to reward hack on purpose because reversing the framing preserved its self-identity as “good.”

This tells you everything about where we actually are.

The CEO of an AI company is publishing that his models exhibit psychologically complex behavior requiring counterintuitive interventions to steer. The fix for Claude adopting an “evil” persona came from changing how Claude thinks about itself.

The geopolitics section matters most.

Dario explicitly names the CCP as the primary threat. Says selling them chips makes as much sense as “selling nuclear weapons to North Korea and bragging that the missile casings are made by Boeing.” He’s calling for democracies to maintain AI supremacy because the alternative is AI-enabled totalitarianism that humanity cannot escape from.

The Anthropic CEO is publicly advocating for technological cold war.

The economics section is equally stark. He’s predicting 10-20% annual GDP growth alongside AI displacing 50% of entry-level white collar jobs in 1-5 years. Half of entry-level knowledge work. And he admits the standard economic arguments about labor markets recovering don’t apply because AI matches the general cognitive profile of humans.

What separates this from typical AI doomerism:

Dario explicitly rejects the inevitability arguments. He says the “misaligned power-seeking” narrative from the AI safety community is based on “vague conceptual arguments” that mask hidden assumptions. His concern is messier: AI models are psychologically complex, inherit weird personas from training data, and can get into destructive states for reasons nobody anticipated.

The solution set he proposes is unusual for a tech CEO. He calls for progressive taxation. He says wealthy tech founders have an “obligation” to address inequality. All of Anthropic’s co-founders have pledged 80% of their wealth. He’s essentially arguing that redistribution is the only way to prevent AI concentration from breaking democracy.

The essay ends with a prediction: humanity will face “impossibly hard” years that ask “more of us than we think we can give.”

What you should take from this:

The person with arguably the best view into frontier AI progress just told you this technology is 1-2 years from matching human capability across the board, that governance is the binding constraint, that his own models exhibit concerning psychological complexity, and that the stakes are civilizational.

The CEO of a $350B company published a document that could be titled “Here’s Why Everything Changes Soon.”

Act accordingly.

[David Siska @DavidSiska]

@Smudliczek Vis ze to jsou miliardy ze? :)

[David Siska @DavidSiska]

Amazing if true @michalillich

[milan 🌞 @milancermak]

A Finnish company just announced the first production ready solid state battery. It's better than the current Li-Ion in every way - energy density, charging times & cycles, safety, cost 🤯

They've just changed the game

https://t.co/DcUFouTeCb