@SaintSFGil this is also unfortunately kind of a wiki game, so I'd recommend pulling it up and reading what items do as you find them, it can save a lot of headaches.
@SaintSFGil theres a weird kind of dev expectation that everyone is a longterm player, with all the DLC made exponentially harder. If it continues to keep kicking your ass, I'd recommend disabling the DLCs and playing base-game for a bit until you feel comfortable with the mechanics.