Deplorable Scott

[David J Harris Jr @DavidJHarrisJr]

🚨BREAKING: A revolutionary new cancer treatment called Histotripsy is showing incredible promise by literally liquefying tumors using focused sound waves—no surgery, no chemo, and no radiation needed.

Developed by pioneers Dr. Zhen Xu and the late Dr. Charles Cain at the University of Michigan, this FDA-approved technology is now being used at leading hospitals like Johns Hopkins and the Cleveland Clinic.

How it works:
- A robotic arm delivers precise high-intensity ultrasound waves straight to the tumor.
- These waves create tiny gas bubbles inside cancer cells that rapidly expand and collapse.
- The mechanical force destroys the tumor cells, turning the mass into liquid debris that the body naturally clears away.
- It also appears to stimulate the immune system to better recognize and attack remaining cancer cells.
- Because it relies on mechanical disruption rather than heat or radiation, it spares healthy surrounding tissue.

Patients often undergo the quick outpatient procedure and go home the same day. It is currently treating liver tumors, with trials expanding to kidney and brain cancers.

This could be a game-changer in the fight against cancer.

[Pub @PubWanghaf]

I work in the Talarico campaign and I cannot remain silent any longer

I am lifelong, dyed in the wool, blue no matter who Democrat. I have worked in Democrat politics since I could hold a job.

James Talarico is severely mentally unwell. He has crippling anxiety. He cannot hold office.

I have to tell the truth.

[Race 🕊️ @multiplanet1]

A retired NASA engineer who had worked on the Space Shuttle program for 25 years was hired by SpaceX at age 62. He described the first week as the most disorienting experience of his professional life.

At NASA, a design change required 3 meetings, 2 committees, a review board, and 6 to 18 months of documentation. At SpaceX, his new supervisor said "if it works, build it. If it doesn't, change it by Friday."

He sat at his desk after the first day and called his wife. He told her he felt like a man who had been swimming with ankle weights for 25 years and someone just cut them off. He could move. He could decide. He could build something in the morning and test it in the afternoon. The constraint that he had accepted as the nature of aerospace engineering turned out to be the nature of bureaucracy.

Within 6 months he had contributed to more design iterations than he had completed in his last 5 years at NASA. Not because he was working harder. Because the time between having an idea and testing the idea collapsed from months to hours. The same brain. The same knowledge. A different operating system.

He described a specific moment where he proposed a modification to a Raptor engine component. At NASA, the proposal would have entered a queue. At SpaceX, the modification was machined by the end of the day and tested by the following morning. He watched his idea become a physical object in 18 hours. At NASA, 18 hours would not have been enough to schedule the first meeting to discuss whether to schedule a meeting.

He told an interviewer: "I didn't get smarter when I went to SpaceX. I got faster. The intelligence was always there. The system was in the way."

The difference between SpaceX and NASA is not talent. NASA has extraordinary talent. The difference is the time between a thought and a test. SpaceX compresses it. NASA elongates it. The same engineer produces 10x more at SpaceX than at NASA because the bottleneck was never the engineer. It was the meetings about the meetings about the work.

[Commentary: President Trump 47 @Trump47News]

🔻 THEY HACKED THE WRONG MAN.

Friday night. Iran's cyber unit breached **FBI Director Kash Patel's personal email.** They published his photos. They thought they'd humiliate him.

They didn't.

They triggered a protocol.

⚡ Within **6 hours** of the breach, Patel activated **CROSSFIRE RETURN** — a counter-intelligence sequence buried inside the FBI's own architecture since January 2025. The hack didn't steal secrets. It **confirmed a location.** Every digital intrusion leaves a return path. Every return path leads to a server. Every server has an owner.

The owner isn't in Tehran.

The owner is on **K Street, Washington D.C.**

🔺 Now connect the dots from the last 72 hours:

**Thursday** — Senator Kennedy looks Patel in the eye at the Senate hearing and asks: **"Did somebody KILL him?"** The room goes silent. Patel doesn't blink. He says one word: *"Yes."*

**Friday** — Reuters publishes a bombshell: **millions in trades** placed BEFORE Trump's Iran announcement. Options. Futures. Prediction markets. Someone knew. Someone always knows. The same accounts. The same clearing house. The same building on **Constitution Avenue.**

**Saturday** — 8 million people flood the streets. "No Kings" they chant. But who organized it? Who funded the buses? Who printed 3 million identical signs in **48 hours?** That's not grassroots. That's a **$47 million operation.** And the money came from the same accounts Reuters just flagged.

**Sunday** — You're reading this.

⟁ Here's what they don't want you to see:

The hack on Patel wasn't Iranian. It was **routed through Iran** to trigger a diplomatic incident — to STOP the ground operation on **Kharg Island.** Because under Kharg Island aren't just oil reserves. There are **vaults.** And inside those vaults are the original ledgers of every transaction between **1979 and 2024** — every dollar that flowed from Washington to Tehran and back.

**$9.7 trillion.** That's the number.

The same number the Federal Reserve blocked Trump from auditing **two weeks ago.**

Patel now has the return path from the hack. It leads to a server farm in **Northern Virginia.** The same server farm that hosted the **Epstein scheduling database** — the one with 14,000 entries that was "accidentally" deleted in 2020.

It wasn't deleted. It was moved. And now they know where.

**⟁ CODE: CROSSFIRE-R / NODE-KP7 / VAULT-79 / APRIL-2**

The ground operation isn't about Iran.

It's about what's **under** Iran.

And the people who hacked Patel just showed him exactly where to look.

Forward this. Before they realize what they've done.

[Rothmus 🏴 @Rothmus]

Knives killed 1,475 Americans in 2025.

Bare hands killed 623.

Rifles of every kind killed 357.

The gun grabbers still want the rifle banned first, because the rifle is the excuse, and under the guise of protection, the goal is a country that cannot shoot back.

Handguns did the real killing, 5,062 of them, plus another 3,837 guns nobody even bothered to classify, but that is the round they save for later.

Once the “assault weapon” is gone they will call the handgun a battlefield pistol, the shotgun a street sweeper, and the armed neighbor a threat to public safety.

[Race 🕊️ @multiplanet1]

During the Falcon 1 era, a machinist working the overnight shift at SpaceX noticed a micro fracture in a propellant valve that had passed quality inspection. The fracture was invisible to the naked eye. He noticed it because the valve made a sound when he tapped it that was slightly different from the sound the same valve should make. He had machined enough valves to know what "right" sounds like. This one was wrong by a frequency he could hear but couldn't measure.

He pulled the valve from the production line at 3am without authorization. By protocol, he should have flagged it for the quality team in the morning. Instead he put it on a bench, photographed it under magnification, and wrote a single sentence on the inspection tag: "this valve will fail under pressure."

The quality team tested it at 8am. It failed. At the pressure levels it would have experienced during flight, the valve would have ruptured. A ruptured propellant valve during ascent is catastrophic. The rocket would have been lost. Depending on the payload, lives could have been lost.

The machinist had no engineering degree. He had 22 years of machining experience. His hands had produced thousands of valves across three decades. The knowledge that saved a rocket was not in a textbook. It was in his fingertips and his ears. A sound that was wrong by a fraction that no instrument in the building would have flagged.

Elon was told about the valve the next day. He walked to the machine shop. He asked the machinist how he knew. The machinist said "I just heard it." Elon nodded and said "that's the most expensive ear in aerospace."

The missions that succeed are not saved by the famous decisions made in boardrooms. They are saved at 3am by a machinist who heard something wrong in a valve that everyone else said was right.

[The Eagle flies free @Fa21519230]

🚨🚨 El renombrado biólogo del cáncer Thomas Seyfried, PhD, revela: "ahora tenemos un mecanismo que explica por qué los medicamentos antiparasitarios están funcionando".
Profesor Thomas Seyfried:
"Mebendazol, Fenbendazol... Realicé una investigación profunda sobre esto y me pregunté: ¿por qué los medicamentos antiparasitarios funcionan contra las células cancerígenas? Resulta que los parásitos utilizan la fosforilación a nivel de sustrato mitocondrial en los tejidos... y el mebendazol y el fenbendazol matan a esos parásitos. Entonces, lo probé en la célula cancerígena y, por supuesto, el medicamento ataca el sustrato mitocondrial y la glucólisis"...
Los parásitos dependen EXACTAMENTE de la misma vía energética disfuncional que las células cancerígenas, y estos fármacos actúan independientemente del hecho de que el cáncer no sea un parásito...
"Entonces, ahora tenemos un mecanismo que explica por qué los medicamentos antiparasitarios están funcionando, aunque el cáncer no sea un parásita"...
Thomas Seyfried menciona haber evitado investigar la Ivermectina debido a la presión política durante la COVID, pero la Dra. Isabella Cooper, PhD en Ciencia Cetogénica e Hiperinsulinemia, le señala el mecanismo:
"La Ivermectina, en realidad, actúa en la vía de muerte celular mitocondrial"...

[Iain Cameron @theiaincameron]

Hudson Bay is actually shrinking rapidly.

Along some of its very flat shores, the coastline can advance by as much as four metres (14 feet) a year as the land rises out of the water.

The cause? Isostatic rebound from an ice sheet that vanished thousands of years ago.

1/n

[NastyMizrableolfart @MichaelRob87481]

It's about fucking time!

[Deep Leaks @DeepLeaksHQ]

I’m sick to my freaking stomach reading Tulsi Gabbard’s declassified bombshells. They laid out the entire treasonous plot: weaponizing the Zelensky phone call to impeach Trump, with Rudy Giuliani squarely in their crosshairs next.

This wasn’t politics—it was a straight-up coup by corrupt deep state actors to overthrow the will of the American people.

These people belong in prison for this shit. Deeply disturbing and downright terrifying.

[Shawn Hendrix 🔜 Homesteaders of America @TheShawnHendrix]

I remember when Fema told us we could not deliver food in an area as it was their work zone, and they had to ensure the safety of their people.

I said thank you for your opinion unless you’re going to forcefully stop me I’m going to go in and deliver food they did nothing.

[Cathlina King 🇺🇸 @AmeraucanaLover]

More Bureaucratic Bullshit‼️

Let the people eat them if they want.

Ted Nugent made a claim about sandhill cranes that sounded so ridiculous I had to fact-check it. Turns out, he was right. In Michigan, farmers can get federal permission to kill sandhill cranes that are destroying crops, but they can’t keep the birds and eat them. We’re talking about the “ribeye in the sky,” one of the most prized wild game meats in the country. Instead, those birds have to be turned over to be thrown in a dump.

Because sandhill cranes are migratory birds, this falls under federal depredation rules. Under 50 CFR 21.100, farmers can be authorized to kill a limited number of crop-damaging birds, but the cranes must be retrieved, handled according to the permit, and cannot be used for human consumption. In other words. The government says the bird can be killed because it’s causing damage, but eating it afterward is where they draw the line.

That makes absolutely no sense. Farmers are losing crops, enough cranes are causing problems that permits are being issued, and hunters across the country consider them the best wild game meat. Yet instead of creating a common-sense system where that meat can actually be used, we kill the birds and throw them away. Kill it to protect the crop? Fine. Feed somebody with it afterward? Nope. Government logic at its finest. Ted Nugent was right.

— Stephen Ziegler
Outdoor writer | Rack Junkies Podcast

[Brian Roemmele @BrianRoemmele]

THIS IS BIG!

The Cancer Cells That Changed Their Minds

A KAIST team just reversed cancer without killing a single cell — and the method may matter more than the result.

For a century, oncology has had exactly one strategy: find the cancer and destroy it.

Chemotherapy poisons it. Radiation burns it. Surgery cuts it out. Immunotherapy teaches the body to hunt it. Every weapon differs in precision, but not in philosophy. The tumor is an enemy. You win by killing.

Now a team at South Korea's KAIST has proposed a heresy: *what if the tumor doesn't need to die?*

In a study led by Professor Kwang-Hyun Cho of the Department of Bio and Brain Engineering, published in Advanced Science ("Control of Cellular Differentiation Trajectories for Cancer Reversion," DOI 10.1002/advs.202402132), researchers took colon cancer cells and — without poisoning, irradiating, or cutting them — turned them back into normal cells.

Not dead. Not damaged. Just normal again.

The tumors, grown in mice, shrank dramatically. The surrounding tissue was left intact, because there was never an attack to survive.

This is early research — cell lines and animal models, no human trials, real obstacles still unsolved. But the conceptual break is the story. For the first time, cancer treatment has a second verb. Not just destroy. Also: convert.

The digital twin of a cell

The KAIST team's insight begins with a redefinition of what cancer is.

The conventional view treats cancer as a pile of broken machinery: mutations accumulate, checkpoints fail, cells proliferate. Cho's group looked at the same evidence and saw something different — a trajectory. During oncogenesis, they observed, normal cells don't just break. They regress, sliding backward along the differentiation path they followed when they matured. A colon cell becomes, in effect, a confused stem cell: immature, proliferative, lost.

If cancer is a wrong turn on a developmental road, then the treatment question changes. You don't blow up the road. You build a map and find the turn.

That map is what the team calls a digital twin — a complete computational model of the gene network governing a cell's differentiation. Using data from 4,252 intestinal cells, they reconstructed a network of 522 interacting components, capturing how genes regulate one another as a cell matures or degrades.

Then they did the audacious thing: they asked the simulation which levers, flipped together, would push a cancer cell back down the road toward normalcy.

The answer came through a system they built called BENEIN (Boolean Network Inference and Control), which models gene interactions as logical relationships and systematically tests which interventions redirect the network's state. The simulation pointed to three master regulators — the genes MYB, HDAC2, and FOXA2 — acting together as the switch that holds the cancerous state in place.

Turn all three off simultaneously, the model predicted, and the cell would stop proliferating and differentiate into something resembling a normal intestinal cell.

They tested it, and it worked.

In three colon cancer cell lines, suppressing MYB, HDAC2, and FOXA2 together strongly induced differentiation into normal-like cells. The cancer cells began expressing markers of healthy intestinal tissue. Proliferation collapsed — not because the cells died, but because they grew up.

In animal models, tumors formed from the reprogrammed cells were dramatically smaller than controls, and under the microscope they looked far more like normal tissue. The signature achievement, and the one that would matter most to any patient reading this: there was no collateral damage. Nothing was poisoned, burned, or irradiated. The healthy tissue never came under fire, because there was no fire.

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[Bernd Kaiser @Bernd_Kaiser_BD]

Die Japaner haben offensichtlich völlig den Verstand verloren. Anstatt jedem Zuwanderer sofort ein Leben auf Kosten der heimischen Steuerzahler zu finanzieren, drehen sie den Spieß doch glatt um.
Ein handfester Skandal!

Japans Regierungschefin Sanae Takaichi macht das dauerhafte Aufenthaltsrecht zu einem echten Privileg – und beendet das staatliche Gratis-Abo.
Wer dauerhaft bleiben will, zahlt künftig 200.000 Yen Gebühr.
Eine gnadenlose Verzwanzigfachung!
Und es kommt noch schlimmer:
Man verlangt allen Ernstes, dass Einwanderer ein Einkommen auf dem Niveau eines normalen japanischen Haushalts nachweisen, ihre eigenen Rentenansprüche sichern und – man wagt es hierzulande kaum auszusprechen – die Landessprache beherrschen sowie die gesellschaftlichen Regeln respektieren.
Wer auch nur mit alten Steuerschulden auffällt, hat verspielt.

Wo bleibt da bitteschön die bedingungslose Willkommenskultur?
Wie kann ein Staat nur knallhart erwarten, dass Migranten dem Land einen Mehrwert bringen, statt umgekehrt?
Wir wissen schließlich:
Einwanderung muss die Einheimischen Milliarden kosten, sonst ist sie einfach nicht bunt und tolerant genug.

Das Schockierendste an diesem japanischen „Irrweg“?
Die Bürger feiern ihn.
Die Zustimmungswerte der Regierung schießen in die Höhe, weil das Volk ein Gefühl von Gerechtigkeit zurückbekommt.
Währenddessen stottert man sich hier von einem wirkungslosen Gipfel zum nächsten.

Vielleicht sollten unsere Politiker eine Studienreise nach Tokio buchen.
Aber Vorsicht: Dort regiert gesunder Menschenverstand.
Das könnte das Berliner Weltbild irreparabel zerstören.

#Takaichi #Japan #Migration

https://t.co/Q5VDYBac27

[SaltyGoat @SaltyGoat17]

The fact that the price of gas in Texas is ~$3.70 a gallon and ~$6.70 a gallon in California shows you a few things

1. It's NOT Trump
2. It's NOT Iran
3. IT IS destructive Democrat policies in California

Don't let Gavin Newsom within 100 miles of the White House!!

[Lara Logan @laralogan]

Have to admit, he has a point….

[AcmeAcres.us @idahobeef]

A coyote pairs for life. Kill one and eight others take his place.

That is the arithmetic of a vacant territory.

Greg Judy laid it out on The Stockman Grassfarmer this week. A pair of coyotes holds a home range and defends it. Remove one and you have disrupted the balance. What moves in is a crowd of hungry transients, not a single animal.

Oklahoma hired a professional hunter. He took about 80 coyotes in one winter. The next year the coyotes came in droves. Guard dogs did not stop them. The sheep had to be driven behind an electric fence every night to keep them off.

There is a book about a rancher who was convinced prairie dogs would bankrupt him. He hired a hunter and a trapper and exterminated the coyotes outright. Then the prairie dogs came and took the farm.

His conclusion, written down: every farmer who buys a ranch should keep pliers, a hammer, and two goats in his toolbox.

Nature does not tolerate monoculture. Each species you build a home for on your ground supports eight others. The more different creatures you can attract to a place, the stronger that place gets.

That is why we run the ranch as a web. Diversity pays the feed bill.

Your rancher,
Jason Hanley | 208-714-0478