A wonderful collaboration with the medicinal chemistry lab of Alexios Matralis and valued colleagues! First small molecule leads targeting #fibroblast activation driving chronic #inflammatorydisease and #fibrosis.
Yes! It's public! Our lab's new work providing the first evidence of spatial spreading of intestinal inflammation via distinct fibroblast subsets. Amazing work .. all because of amazing Lida et al! @BSRC_Fleming@CrohnsColitisFn@ERC_Research https://t.co/ODPspDapn7
Proud and extremely happy to see our recent work published today @NAR_Open! Congratulations to all the (past and present) members of the #MFlab@BSRC_Fleming that contributed!
https://t.co/pOgXLk9DGu
Repurposing the antipsychotic drug amisulpride for targeting synovial fibroblast activation in arthritis: https://t.co/MmO6Pr6Afa
@KolliasLab@BSRC_Fleming#Therapeutics
Kollias and colleagues examine FRC development during lymphoid organogenesis in gut PP: two separate mesenchymal cell lineages converge and form mosaic microenvironments that support immune cell activation and maintain intestinal homeostasis https://t.co/KCniKQSAH0