Dr. Sharath Kumar H J

[Vikram gota @vikram_gota]

One of our most significant works thus far.
Immunomodulation by juglone alleviates acute graft‐versus‐host disease without compromising the graft‐versus‐leukaemia activity in mice - Gohil - British Journal of Pharmacology - Wiley Online Library https://t.co/z3tYdNMjau

[VIKRAM GOTA @GotaVikram]

Our earlier study identified sig covariate effect of CrCl on PEM clearance (J Clin Pharmacol. 2019;59(9):1216-24). Went on to test the effect of ADME gene polymorphisms, importantly SLC19A1. Interestingly ADME SNPS do not affect PEM PK. @DrSharathKumar6 @srini_meen @VanitaNoronha

[Saurabh Gupta @SKGUPTA_94]

@GotaVikram @pumas_ai @vijay_ivaturi Congratulations @DrSharathKumar6 great collaboration leads great research. Kudos to @GotaVikram and @pumas_ai for opening new avenues.

[VIKRAM GOTA @GotaVikram]

ClinPharm @ACTREC_TMC welcomes @DrSharathKumar6 & Bhavatharini for this much anticipated project. @akchichra @lingarajnayak @AnantRamaswamy @VikasO @VanitaNoronha @DrVijayPatil11 @AmitJos93188352

[VIKRAM GOTA @GotaVikram]

Looking forward to an exciting collab with @pumas_ai @vijay_ivaturi for the validation of Lyv algorithm for #TDM. Expect new trends for informed decisions on dose adjustments in #bmt and #oncology in the sub-continent.

[Shruti Pathak @Shru375]

Paclitaxel plus Carboplatin with OMCT as NACT in LAHNSCC. ASCO 2022, Poster board number #22
@DrVijayPatil11 @VanitaNoronha @Nandinimenon18 @ZoyaPeelay

Utterly grateful to Dr Vijay Patil Sir @DrVijayPatil11 for this once in a lifetime opportunity.

[VIKRAM GOTA @GotaVikram]

PopPK of imatinib showing the effect of ABCB1 gene polymorphisms on imatinib clearance published @springernature in @ejcp. #ADMEgenes #pharmacokinetics. https://t.co/qeEOeqkYWp

[Saurabh Gupta @SKGUPTA_94]

Glad to share my first Ph.D. paper where we aimed to bring Withaferin-A one step closure to clinics by establishing it's toxicity and pharmacokinetics.
Kudos to @GotaVikram and the Clinical Pharmacology group from @ACTREC_TMC to achieve this milestone.
https://t.co/ho4Z8xBdmQ

[VIKRAM GOTA @GotaVikram]

Safety, toxicity and pharmacokinetic assessment of oral Withaferin-A i... https://t.co/aMDz10IgMa
Established the safety of Withaferin-A administered in its pure form. A milestone in the systematic development of WA as immunomodulator @akchichra @lingarajnayak @ministryofayush

[VIKRAM GOTA @GotaVikram]

Congratulations Dr. Neha Singh for winning the best protocol award @aazpire2022. Kudos @TMC_Varanasi

@VanitaNoronha @RimaPathak1 @GirishTMH @ACTREC_TMC @Oncology_at_AZ @Utkarsh67560307