#Myeloma Paper of the Day: Circulating tumor cells (dependent on 1⁰ genomic events, high-risk 2⁰ events (amp 1q, del 1p, del 13q, biallelic TP53 mutations, increased APOBEC)) are compound biomarker for BM high-risk genomic alterations/tumor load: https://t.co/2Epk2nX5ph. #mmsm
#Myeloma Paper of the Day: Selective depletion of B-cell subsets (mature, immature and small pre-B cells + normal PCs) underlies increased risk of infection in myeloma patients treated with anti-BCMA versus anti-GPRC5D bispecific T-cell engagers: https://t.co/dLuFqTvHpN. #mmsm
#ASH2025 first of three abstracts from the European CTC consortium #mmsm@Dagostino_MD shows how CTCs are complementary to the R2-ISS and IMS/IMWG genomic risk score, supporting the future integration of CTCs in myeloma staging!
@LucaBertamini@TomasJelinekMD@DZihala
#Myeloma Paper of the Day: Study of extramedullary myeloma tumor microenvironment finds significantly reduced effector-to-tumor ratio, fewer CD4⁺ T cells, more regulatory CD16⁻ NK cells, higher proportion of exhausted, tumor-reactive CD8+ T cells: https://t.co/42xtmO0ekj. #mmsm
📢We are thrilled to invite you to XX. Myeloma & VIII. Cell Therapy Workshop, organized by Blood Cancer Research Group and Czech Myeloma group 📢
Join us in Ostrava 🇨🇿 for 2-day multidisciplinary workshop 🧬
Save the date and follow us for more updates!
#Myeloma Paper of the Day: Spatial transcriptomics reveals profound subclonal heterogeneity and T-cell dysfunction (exhausted TIM3+/PD-1+ T-cells) in extramedullary myeloma with oxidative phosphorylation representing the major metabolic program: https://t.co/DhA5WYmVKY. #mmsm
We talk about diversity & inclusion in academia BUT:
-open access journals with 5k$ publication fee
-congresses with >50$ submission fee and registration fee of 100s of $
-meet the expert sessions you have to pay for
...
Change only happens when we act instead of pretend!
📢Happy to share our new paper recently published in @LeukemiaJnl. @TomasJelinekMD and his team conducted a comprehensive NGS analysis to reveal molecular changes from the time of diagnosis to extramedullary #MultipleMyeloma relapse. Congrats to authors🙌🔗https://t.co/vEMFxm4zyu
#preprint
wondering why your assembly is so strange? try Karyon for diagnosing possible causes:
"Karyon: a computational framework for the diagnosis of hybrids, aneuploids, and other non-standard architectures in genome assemblies."
https://t.co/bKNT8n0gxb
Still a few weeks left to apply for the open PhD position in my lab to study #protists diversity & interactions! Read more about the position: https://t.co/RlQIIGIHTg
@UniWarszawski@BiolUW#NCN#MicroDiver
(2/2) I am also hiring 3-4 more PhD students soon, starting Fall 2021 - Fall 2022. If you know anyone interested in working in genomics, microbial ecology, and protists, please send them my way. Official job ads will be out soon. @protistologists @ISEPprotists
(1/2) My latest NSF proposal "PurSUiT: Sampling amoeboid protists as a reservoir of unknown/undescribed eukaryotic diversity" has officially been awarded. In the next few months, I will be recruiting 2 postdocs (microbial ecology and genomics). #NSFfunded@protistologists
Still a few weeks left to apply for this open PhD position to study #anaerobic microbial #eukaryotes (#protists) and their prokaryotic comrades. Read more about the position: https://t.co/je7UyuWjPT
Or student life at @lunduniversity: https://t.co/rToDdgOiHc
We are looking for a bioinformatician with knowledge of microbial 'omics to support ongoing research and education at @MIB_WUR. Come join us! Apply here: https://t.co/BID3jM83oy pls RT!
1/ How do microbial eukaryotes and prokaryotes work together to survive in anoxic environments? Come join my lab at @Biology_LU as a PhD student to investigate the #evolution and #molecular basis of metabolic syntrophy in anaerobic #protists. #phdpositions https://t.co/je7UyuWjPT
Identification of resistance pathways and therapeutic targets in relapsed multiple myeloma patients through single-cell sequencing. Great congrats Yael, Ido and team! @NatureMedicine #mmsm @IMFmyeloma @theMMRF @myelomacrowd https://t.co/Q7lp8jfG7o