Our work, @ron_dorit lab in collaboration with @kevansf and @bignerdzzy is out! This dual drug strategy that reduces alcohol consumption in mice, allows mTORC1 inhibition specifically in the brain while protecting the periphery from sides effects :
https://t.co/xacX4APAF5
Our last preprint in collaboration with Kevan Shokat and Ziyang Zhang is out!Brain-specific Inhibition of mTORC1 by a Dual Drug Strategy: A Novel Approach for the Treatment of AUD https://t.co/3d1dv1wxE4
Paper of the week: excellent @NPP_Journal paper of Ron and Alvarez labs showing a role of cAMP-Fyn signaling in dorsomedial striatum direct pathway in homecage alcohol intake in mice
https://t.co/NAMEMd7cNC
cAMP-Fyn axis in the DMS dMSNs is a molecular transducer of mech