How to Remember 4th and 5th Gen. Cephalosporins!
☑️Fourth Generation
- cefepime
- cefpirome
All contain "pi" + "me" within their names.
☑️Fifth Generation
- Ceftobiprole
- Ceftaroline
- Ceftolozane
All contain "ceft" + "ol" within their names.
💊Montelukast is the active ingredient of the medicine, Singulair; a drug used in the maintenance treatment of asthma.
Montelukast works as a leukotriene receptor antagonist - blocking the action of leukotriene D4 in the lungs, causing smooth muscle relaxation.
Baricitinib works by acting as an inhibitor of JAK1 and JAK2; a drug used to treat rheumatoid arthritis.
Lapatinib = interrupts HER2/neu and EGFR pathways.
Sunitinib = targets VEGFRs and platelet-derived growth factor receptors.
Nilotinib = Bcr-Abl tyrosine kinase inhibitor.
Spironolactone is a steroid that blocks the effects of testosterone whilst also having estrogen-like effects; a drug used as a K-sparing diuretic.
Side effects with spironolactone include:
- gynecomastia
- hyperkalemia
- electrolyte abnormalities
- mood changes
- reduced libido