Ellis Bio

Revolutionizing DNA methylation analysis with ultrafast and ultramild bisulfite conversion. 🧬Discover the difference with our SuperMethyl test kit! #EllisBio

[Ellis Bio @Ellis_Bio]

New @Roche Tech Spotlight: a side-by-side look at 5 low-input cfDNA methyl-seq workflows on a single KAPA EvoPrep® library prep. SuperMethyl™ Max came in highest on conversion accuracy and lowest on false-positive rate. https://t.co/ZAfu9WAMG6

#methylation

[Ellis Bio @Ellis_Bio]

Paper: Cheng, Ouellette, Skead et al., Cell Genomics (2026) https://t.co/qXXge4k6yu

[Ellis Bio @Ellis_Bio]

Cancer may leave a trace in blood years early. New in Cell Genomics: cfDNA methylation signals in plasma drawn up to 8 yrs before breast and prostate cancer diagnosis, from just 1.6 mL per person. Signals were modest, and sample quality mattered. 🧬 #DNAmethylation #cfDNA

[Ruitu Lyu @RuituLyu]

Fair point on conventional bisulfite: harsh conversion fragments DNA and costs coverage. That's why we built SuperMethyl™ Ultra-Mild Bisulfite chemistry. 99.8% conversion with almost no DNA damage. Happy to run a head-to-head on matched samples. 🧬

[Ellis Bio @Ellis_Bio]

Organs follow their host's epigenetic clock, not their birth certificate. 🧬 A striking use of DNA methylation from Poganik et al., and a reminder that precise age calls from small biopsies start with clean conversion.

[nature @Nature]

Hearts from young donors age rapidly in the bodies of older recipients, and older hearts are rejuvenated inside young people

https://t.co/f8JG7MiryQ

[Ellis Bio @Ellis_Bio]

@NatureBiotech Durable silencing from transient expression is a big step for epigenetic editing. High-accuracy, base-resolution methylation readouts will be key to tracking on- and off-target effects over time.

[Ellis Bio @Ellis_Bio]

Not all clock noise is biology. Incomplete conversion and DNA loss during bisulfite treatment add technical variance at individual CpGs, especially with low input. Measuring noise is a great step; minimizing it at the bench is the other half.

[Aging Journal @AgingJrnl]

#PaperoftheDay: "Fail-tests of DNA methylation clocks, and development of a noise barometer for measuring epigenetic pressure of aging and disease"

DOI ⬇️
https://t.co/4dTqGIecaO

#Aging #Research #OpenAccess #Gerontology #PeerReviewed #Journal #Publishing

[Ellis Bio @Ellis_Bio]

An FDA panel just voted 7-2 that Galleri's benefits outweigh its risks. Blood-based cancer screening through cfDNA methylation is getting close.

Every one of those tests depends on converting trace amounts of fragmented DNA without losing any. That's what SuperMethyl™ is built for. 🧬 #DNAmethylation #cfDNA

[GRAIL @GrailBio]

Today GRAIL announced a favorable vote from an FDA Advisory Committee for the approval of the Premarket Approval application of the Galleri multi-cancer early detection test (MCED).

The Committee considered Galleri’s safety, effectiveness, and overall benefit-risk profile for screening for the early detection of multiple types of cancer in adults aged 50 years and older.

Read more: https://t.co/Hm97ydCD8y

#MCED #Galleri #CancerScreening

[Ellis Bio @Ellis_Bio]

Full Roche Tech Spotlight: https://t.co/ZAfu9WAMG6 — SuperMethyl Max is available now.

For Research Use Only. Not for use in diagnostic procedures.

[Ellis Bio @Ellis_Bio]

New @Roche Tech Spotlight: a side-by-side look at 5 low-input cfDNA methyl-seq workflows on a single KAPA EvoPrep® library prep. SuperMethyl™ Max came in highest on conversion accuracy and lowest on false-positive rate. https://t.co/ZAfu9WAMG6

#methylation

[Ellis Bio @Ellis_Bio]

Targeted methyl-seq: paired with KAPA HyperCap®, SuperMethyl Max delivered ~2X higher mean target coverage on gDNA, directly relevant for liquid biopsy and MRD research.
#liquidbiopsy

[Ellis Bio @Ellis_Bio]

Ellis Bio looks forward to seeing you in San Francisco on January 12, 2026 for the Midwest Biotech Startup Showcase!

This event is for investors and founders only, register at https://t.co/JYBDbAPXOX

#JPM2026 #JPMWeek

[Ellis Bio @Ellis_Bio]

We are excited to celebrate the publication of the new Nature Communications article highlighting the impact of Ultra-Mild Bisulfite Sequencing (UMBS), a major advance that addresses long-standing limitations in DNA methylation analysis.
https://t.co/2pC78b4rGR

#dnamethylation

[Ellis Bio @Ellis_Bio]

That's a wrap for day one at ASHG 2025. Excited for day two!

Remember to stop by our poster this afternoon

Board 4037T – Benchmarking next-generation bisulfite chemistry against enzymatic and conventional approaches for DNA methylation analysis

2:30–4:30 PM EDT

[Ellis Bio @Ellis_Bio]

Our innovative SuperMethyl™ Max kit, developed in collaboration with University of Chicago’s Prof. Chuan He, delivers high-fidelity results with unparalleled DNA preservation, all in just a few hours.
https://t.co/PhFZeDL9Qe

[Ellis Bio @Ellis_Bio]

Don’t miss our poster in the Omics Technologies session:
Board 4037T – Benchmarking next-generation bisulfite chemistry against enzymatic and conventional approaches for DNA methylation analysis

Thursday, October 16, 2025
2:30–4:30 PM EDT
Exhibit & Poster Hall, Lower Level

[Ellis Bio @Ellis_Bio]

Don't miss the train to elevate your methylation research!

Discover how our advanced bisulfite kits deliver high-recovery, fast conversion, and precise results. Catch our poster: Omics Tech, Board 4037T on benchmarking next-gen bisulfite chemistry, Oct 16, 2:30–4:30 PM.

[Ellis Bio @Ellis_Bio]

🔬 Experience Lower Unconverted Ratios with Ellis Bio’s UBS Kit! 🧬

Say goodbye to insufficient conversion at specific cytosines in your experiments. Our Ultra-fast Bisulfite Sequencing (UBS) kit excels where others fall short:

📉 Lower Unconverted Ratios = Low False Positives:

Ellis Bio: Low false positives, precise results.
Conventional Kits: Insufficient conversion at specific cytosines.

💡 Benefits:

Enhanced data reliability.
Perfect for accurate methylation analysis.

Choose Ellis Bio’s UBS kit for unmatched performance in your research! 🌟

#EllisBio #Genomics #DNA #Research #Biotech #BisulfiteConversion

[Ellis Bio @Ellis_Bio]

🚀 Speed Matters in Bisulfite Conversion! 🧬

At Ellis Bio, our UBS kit stands out among the competition. Check out how we compare:

🔬 Conversion Speed:

Ellis Bio: 8 mins; The fastest kit in the market!
Competitor A: 8 mins + 1 hr
Competitor B: 2.7 hrs
Competitor C: 5 hrs
🛠️ Efficiency and Accuracy:

💡 Why Choose Ellis Bio?

Save precious time and achieve reliable results.
Ideal for high-throughput applications and tight schedules.
Join the future of DNA methylation analysis with Ellis Bio! 🌟

#EllisBio #Genomics #DNAmethylation #Research #Biotech #BisulfiteConversion

[Ellis Bio @Ellis_Bio]

🔬 Minimize DNA Damage with Ellis Bio’s UBS Kit! 🧬

Traditional bisulfite conversion kits can cause significant DNA degradation. Our Ultra-fast Bisulfite Sequencing (UBS) kit changes the game:

🛠️ Less DNA Damage:

Ellis Bio: Minimal damage, preserving DNA integrity.
Conventional Kits: High levels of degradation.

💡 Advantages:

Reliable results with preserved DNA.
Ideal for sensitive and precious samples.
Elevate your DNA methylation analysis with the superior quality of Ellis Bio’s UBS kit! 🌟

#EllisBio #Genomics #DNAMethylation #Research #Biotech #BisulfiteConversion