Evdokiia

Postdoc at @RibackLab

[Evdokiia @Evdokiia_P]

9/ Thank you to everyone in @Ribacklab and to our amazing collaborators! @sciencyelmira
@SuperSciJew

[Evdokiia @Evdokiia_P]

1/ Do cells use phase separation to adapt biosynthetic output to changing demands? In our new preprint, we show that under nutrient limitation, the nucleolus enters a reversible ‘hibernation’ state that slows ribosome biogenesis. See https://t.co/urNZ4ORD16

[Evdokiia @Evdokiia_P]

8/ More broadly, our findings support a role for phase separation not only in compartmentalizing biochemical reactions, but also in tuning their output to physiological demand.

[Gandhar Datar @Gandhar_Datar]

(1/10) How do diverse leukemia mutations converge on the same molecular program?
In our new study @CellCellPress,the @RibackLab and @Goodell_Lab show that disparate mutations rewire shared protein networks to form nuclear condensates called coordinating bodies (C-bodies).🫧

[Evdokiia @Evdokiia_P]

Our lab's first preprint is out! I'm glad to be part of this project - take a look!

[Josh Riback @SuperSciJew]

In lab's #FIRSTPREPRINT, we present methods to measure nanometer organization around & between specific proteins in condensates. We uncover unexpected heterogeneity for a liquid-like phase with local meshwork spanning 10-50nm, stemming from ribosome biogenesis in the nucleolus.

[Josh Riback @SuperSciJew]

🎉 Thrilled to share the @ribacklab’s first PhD defense! Huge congrats to @Gandhar_Datar and co-advisor @Goodell_Lab ! 🎓🔬 Gandhar’s work in biophysics and leukemia led to the discovery of a new phase-separated condensate that drives leukemias. Stay tuned for more insights!

[Josh Riback @SuperSciJew]

Thanks for being such great hosts @BoeynaemsSteven lab. We in the @RibackLab enjoyed sharing our work and hearing the exciting work from you all and @JLeeLab!!!! #HoustonCondensates #ThreeLabsInTheDensePhase

[Riback Lab - Cellular Physical Chemistry Group @RibackLab]

Congrats to @RibackLab members @Gandhar_Datar (co-advised with @Goodell_Lab) for winning the 3rd place talk award on AML condensate form and function and Kris for her @VisiTech_UK #iSIM microscopy image of nucleoli being chosen for the MCB retreat cover!