Ewan Gerken

PhD Candidate @ The University of Adelaide

Doing cool neuroscience stuff with zebrafish 🐟🧠🔬

[Ewan Gerken @EwanGerken]

Excited to release a preprint on our MPS III #Sanfilippo syndrome zebrafish! 🐟🧠 super interesting results in our quest to understand this disease and help children and families living with childhood dementia!

Thanks to @SFCFoundtn for their vital support of this project!

[bioRxiv @biorxivpreprint]

Zebrafish models of Mucopolysaccharidosis types IIIA, B, & C show hyperactivity and changes in oligodendrocyte state https://t.co/BHjhVCmU1X #bioRxiv

[Ewan Gerken @EwanGerken]

@AFLFantasy Yes, stuck as emergency 😭

[Ewan Gerken @EwanGerken]

@psych_genes Agreed! Time of day is an automatic inclusion as a variable in all our behavioural analyses 🐟 @kariisssaaa

[Ewan Gerken @EwanGerken]

@AFLFantasy @AFL Can only afford one of Green or Gulden this round, whoever I don't trade in will come in next round. Love the value of Green but don't want to miss a juicy matchup for Gulden this week. Green will still be value next week?

[Ewan Gerken @EwanGerken]

@AFLFantasy Trade out strategy: Graham, Colby, H. Thomas, Garcia, or others who are selected like Keane?

[Ewan Gerken @EwanGerken]

@AFLFantasy @AFL Hey fellas, got a bucket of issues this week

How do I prioritize trade outs for the following players?

Blakey, Horne-Francis, Dempsey, Roberts, Keane, now Graham. If I trade the first two I can bring in Serong AND another premo.

[Ewan Gerken @EwanGerken]

Media release from the @SFCFoundtn giving an update on our work. Interesting findings, however we have lots more to learn! 🐟🔬👨‍🔬

[Sanfilippo CFoundtn @SFCFoundtn]

Project Update: A/Prof Michael Lardelli from @UniofAdelaide & team have completed their Incubator project funded by @SFCFoundtn to develop 3 new zebrafish models of #Sanfilippo & undertake behavioural & transcriptomic analysis: https://t.co/PC76B26v2Z #ChildhoodDementia @ADandCD

[Ewan Gerken @EwanGerken]

A story from the ABC on the impact and challenges of #Sanfilippo syndrome for families. Pretty clear that more research into #childhooddementia is needed! 🧠🔬

https://t.co/CuiyoVs5bE

[ABC News @abcnews]

You might know of dementia as mainly affecting older Australians, but in rare cases, it also affects children. Families say childhood dementia is underfunded and under-researched, and they want greater public awareness to help improve their children's lives. #abc730

[Ewan Gerken @EwanGerken]

@kariisssaaa @agrayseal Lol @agrayseal it's not bedtime yet! 😴

[Ewan Gerken @EwanGerken]

@TimSargeant1 Disappointed I couldn't make it this year! I'm sure @kariisssaaa will keep me informed of any cool lyso/auto work that is presented 🙏🧠♻️

[Ewan Gerken @EwanGerken]

Thanks to The #Sanfilippo Children's Foundation for asking me to appear on their website 😊 here I give some insights into my research motivations and hobbies outside of the lab 🔬🧠⚽️🏕 definitely need to work on my photogenicity though 😂

#researcherprofile

[Sanfilippo CFoundtn @SFCFoundtn]

Ewan Gerken is a PhD Candidate at The University of Adelaide who uses zebrafish models of Sanfilippo and early-onset Alzheimer’s Disease to study how these diseases affect the brain’s cells and zebrafish behaviour. Read more about his work: https://t.co/TVrcZjw6NQ

[Ewan Gerken @EwanGerken]

https://t.co/zBsFol7Sxk

[Ewan Gerken @EwanGerken]

Yesterday was World #Sanfilippo Awareness Day! In true PhD student fashion I was in the lab until 10pm 🐟🧪 however on my way home I managed to grab this late night pic of Adelaide Oval lit up beautifully in support of Sanfilippo syndrome 💜 to learn more head to @SFCFoundtn

[Ewan Gerken @EwanGerken]

I can say from sitting next to him every day that Lachie has put immense effort into making this an elegant and efficient package! 📈

@baerlachlan can I claim authorship for helping with the name? 🧐

[Lachlan Baer @baerlachlan]

tadar is now available with the release of Bioconductor 3.18! My first R package and another one for @stevie_ped 🥳 tadar enables Differential Allelic Representation analysis, improving our inferences from RNA-seq data in non-isogenic organisms.
More info: https://t.co/OMhdnP8jzD

[Seb Dworkin @DworkinSeb]

Networking in Adelaide

[Dr Meming @Dr_Meming]

When somebody asks if you’ve figured out what you want to do after your PhD

[Ewan Gerken @EwanGerken]

We at the Lardelli lab are big fans of cost efficiency 🤩

[Karissa Barthelson @kariisssaaa]

Got sick of buying PCR enzymes so we made our own! 100 mLs of taq that's going to last us years! @AcademicChatter

[Ewan Gerken @EwanGerken]

@kariisssaaa @AcademicChatter @agrayseal @kariisssaaa not as expensive to drop a plate of PCRs on the floor now! 😁

[Ewan Gerken @EwanGerken]

@BrownRyan97 @PeterMacCC Bit of a celebrity mate! Awesome! 🤝

[Ryan Brown @BrownRyan97]

Congratulations @EwanGerken & authors! An awesome preprint that uses zebrafish to model the #RareDisease, Sanfilippo Syndrome! 🐟 🎉

[Lachlan Baer @baerlachlan]

Woohoo! Our lab's first manuscript of Sanfilippo syndrome zebrafish models. Lots of information on the generation and characterisation of mutants, RNA-seq analysis and behaviour assays in this one.