Trientine and Penicillamine on copper uptake:
🔸Oral 64-Cu PET/CT
🔸TRI reduced 64-Cu intestinal uptake 50%!
🔸Similar to Zinc [Munk et al]
🔸Time for separate 24H-urine copper targets for TRI monitoring?
OA: https://t.co/LTnAFYFKay
@AarhusUni@HepGas@HEP_Journal#livertwitter
What do we actually know about European Management of #WilsonDisease? Thanks to our latest paper in @ojrarediseases we now know a bit more!
🔎 Rather high level of uniformity in care!
🔸 Variations in e.g. Initial treatment of non-hepatic WD, diet restrictions and more! @HepGas
Diagnosing #WilsonDisease in #AcuteLiverFailure
✅ ALF of unknown ethiology
✅ If low ALT, measure total serum copper
✅ If s-Cu-ALT = 2 or more ASSUME WD
✅ While LTx is prepared, perform genetic testing
Recent work by our group from @HepGas
We explore how to identify #WilsonDisease in patients with #acuteliverfailure in @AmJGastro! 💥
Full paper & Visual abstract coming soon 🌞 - with a neat guide How To ✅
Diagnosing Wilson Disease in Acute Liver Failure: Comparison of existing and experimental biomarkers.
@AmJGastro 🔐https://t.co/x8lDmJDs4O
#Wilson#ALF#LiverTwitter#LiverX
Diagnosing Wilson Disease in Acute Liver Failure: Comparison of existing and experimental biomarkers.
@AmJGastro 🔐https://t.co/x8lDmJDs4O
#Wilson#ALF#LiverTwitter#LiverX
💡Relative Exchangeable Copper: an excellent tool for diagnosing Wilson Disease!
💡Total Serum Copper: Surprisingly solid tool as well!
🌞Very happy to be part of this big collaborative effort with our friends from Spain!
#LiverTwitter@LiverInt
https://t.co/v20TyYMH0B
#WilsonAarhus symposium - How to screen for #WilsonDisease in the future?
Dr Hahn (Seattle) on prospects and newest knowledge in this critical field.
Atp7b peptide screening in newborns looks very promising!
Screening = early detection = better patient outcomes!
#LiverTwitter
First day of the #WilsonAarhus symposium!
Cognitive function in WD:
⁃Cognition = QoL
⁃Also in some with hepatic WD
⁃Often improves on chelation therapy
⁃Tips on how physicians can help people with cognitive issues.
Thank you @shribbers#LiverTwitter#WilsonDisease
Looking forward to the 3rd #WilsonAarhus meeting in Aarhus, @HepGas
More than 100 experts will share the newest knowledge - a big win for professionals and patients alike.
X Takeover for the weekend, as we are hosting the 3rd Wilson Aarhus Symposium! 🎓🩺
100+ #WilsonDisease experts will share newest knowledge and help us provide the best possible management!
We will hold lots of sessions and share more throughout 😎
#LiverTwitter#WilsonAarhus
1/ 🚀 JHEP Journal Club🚀
Novel Insights into the Mechanism of Action of the Copper Chelator Bis-Choline Tetrathiomolybdate (TTM) in Wilson's Disease (WD)‼️
🔓https://t.co/uU2v9AXuJo
🫤Wilson👉 Cu2+ load in liver & brain
Frederik Teicher Kirk & cols 🔎 TTM👇👇
@livertwitter
@SMDBaunwall has been selected as a finalist for the annual PhD Cup! He will present his exciting research on fecal transplantation and gut bacteria, of which we are very proud! Learn more here and watch the show on Saturday at 19:00 on DR
https://t.co/fOxfCyLbHj
@HepGas
#WilsonDisease research from Aarhus on the frontpage in @HEP_Journal.
Right in time for the 2024 Wilson symposium in #Aarhus.
Impressive team effort that led to this honor. Thank you @Thomas_Sandahl and the rest of the team!
#LiverTwitter.
Pinned post explains the study.