Gabe Shaya MD MPH

Cardiologist . ❤️ Imaging, lifelong learner

[Gabe Shaya MD MPH @GabeShaya]

@drjohnm Why compare to aspirin? How about nothing (if aspirin not otherwise indicated)?

[Gabe Shaya MD MPH @GabeShaya]

@nntaleb interesting thought. Can you point to data supporting this assertion? What would be “optimal” LDL; in which population?

[Gabe Shaya MD MPH @GabeShaya]

1. Many professional medical society guidelines regarding essentially every chronic disease points to the importance of healthy lifestyle habits. How do you frame that as ignoring?

2. Changing lifestyle habits is notoriously difficult even in the most intensive clinical trial settings. “Telling” somebody to practice healthy habits is not likely to be effective, especially in those who are most vulnerable. Depression, by definition, manifests in difficulty practicing healthy habits. Similarly, it is not effective to “tell” people with obesity to eat less and burn more calories…obviously

3. Healthy lifestyle and medications need not be viewed as mutually exclusive.

4. Any evidence that eating steak cures depression? Curious about this.

[Nick Norwitz MD PhD @nicknorwitz]

🚨FINALLY! The Lean Mass Hyper-Responder 1 Year Data Just Dropped!🚨
https://t.co/7W4ac4jl2b

🫀Most participants showed NO OR MINIMAL or progression of coronary plaque
🫀Neither ApoB nor LDL exposure predicted plaque progression
🫀But plaque predicted plaque progression, leading to the conclusion and Title:

1/10) 🧵This thread will give you some high-level points, direct you to more information, and tell you how 🫵YOU🫵 can help change “the science”

(🔗 links at the end!)

ht/ @realDaveFeldman @AdrianSotoMota @Metabolic_Mind @janellison @bschermd @BudoffMd @khurramn1

[Rick Steves @RickSteves]

Repeating lies endlessly, the fascist leader promises quick solutions and simple answers to complicated problems.

Stream my hour-long special “Rick Steves’ The Story of Fascism in Europe” at https://t.co/IyqHmfNqJx.

[Ash Paul @pash22]

Have the benefits of statins been overstated?
https://t.co/qfJ4htmjow via @pbyrne82

[Gabe Shaya MD MPH @GabeShaya]

@aknabdMD @MarkDSiegel1 @YaleIMed @TradIMYale Amazing Ashkan congratulations

[Gabe Shaya MD MPH @GabeShaya]

Thought provoking trials, but not entirely sure how much weight to put on hospitalizations/symptoms without blinding. We know there is favorable remodeling post TAVR as redemonstrated. This, compared to known hard adverse procedural events (ie pacemaker). Wouldn’t mind the placebo question as much were it not for cost and known procedural risks. High rate and relatively short time to conversion may also go away with blinding.

[Gabe Shaya MD MPH @GabeShaya]

@VPrasadMDMPH Agree that waste should be avoided. Do you think this will create an avenue for an uptick in industry-funded research to fill the void?

[Gabe Shaya MD MPH @GabeShaya]

@RichardAFerraro @JACCJournals Corroborates our experience @WellSpan with PCCT over the last year. Exceptional ability to get actionable answers despite high calcified plaque burden and stents saving patients from unnecessary invasive procedures. Hopefully will promote more excitement for cardiac CT generally!

[Gabe Shaya MD MPH @GabeShaya]

@VPrasadMDMPH ❤️ “dingbat”

[Gabe Shaya MD MPH @GabeShaya]

Provocative

https://t.co/0sWFUZNUTr

[Khurram Nasir @khurramn1]

Another #PowerOfZero triumphs 🙂

[Gabe Shaya MD MPH @GabeShaya]

@rblument1 @CiccaroneCenter @hopkinsheart @seamuswhelton Congrats @seamuswhelton !

[Kevin S Shah, MD @KevinShahMD]

@VPrasadMDMPH Traveling in-person for interviews (residency and fellowship) really pushed the applicant to showcase their interest because you had to (1) find coverage, (2) pay for hotel/travel, and (3) show up in person. It was not perfect, but it helped both sides in many ways.

[Gabe Shaya MD MPH @GabeShaya]

@khurramn1 Perhaps QoL metrics should’ve been the primary outcome? I don’t think monitor-measured AF burden is patient-centric or particularly important unless linked to clinical outcomes or QoL.

[John Mandrola, MD @drjohnm]

The first sham-controlled AF ablation trial has been done. Twenty years (and millions of procedures) after we started doing this procedure.

The study has limitations but it is a big step forward. I need to take some time to sort it out.

For now, though, our profession should have been bolder and humbler about this much sooner. #ESCCongress

[Gabe Shaya MD MPH @GabeShaya]

@RichardAFerraro Need head to head vs spiro.

[Gabe Shaya MD MPH @GabeShaya]

@rblument1 @CiccaroneCenter @ErinMichos @hopkinsheart Congratulations! @ErinMichos

[John Mandrola, MD @drjohnm]

In my work with @AndrewFoy82 @MRuzieh over at @CVtrials I discovered another shocking trial.

Pts with severe CAD. One group gets PTCA (fixed). One group gets tablet (atorvastatin)

AVERT trial
https://t.co/UVSgbl8PZt

Amazingly -- LOOK AT THIS DATA for major adverse events