Gharpure Lab

This group focuses on synthesis of natural and unnatural product and developing new synthetic methodologies.
Student-run twitter account for Gharpure Lab IITB..

[Ponneri C Ravikumar @ravikumar_lab]

A symposium on Innovations in Natural Products and Synthetic Strategies (INPSS) was held at The Park Hotel, Hyderabad. The event was organised in honour of Prof. A. Srikrishna's 70th Birthday. Eminent speakers from across India delivered insightful talks on cutting-edge research.

[J Org Chem/Org Lett @JOC_OL]

In #OrgLett: @GharpureLab from @iitbombay shares a unified strategy for the synthesis of spiroketals from cyclopropenes! @sjgharpure, @guptakrish50 https://t.co/opEGZdR2PJ

[J Org Chem/Org Lett @JOC_OL]

In #OrgLett: @GharpureLab reports MHAT segment coupling of alkenols with acceptors via C-C radical translocation and remote oxidative 1,5/6-hydrogen atom transfer

@sjgharpure, @RupaliSChavan, @DipakFartade

https://t.co/ApaRFhgxOk

[J Org Chem/Org Lett @JOC_OL]

In #OrgLett, @GharpureLab from @iitbombay demonstrates PIDA mediated keto-oximation of O-alkynyl hydroxylamines for the synthesis of 3-acyl isoxazolines and 1,2-oxazines.

@sjgharpure, @kaushikpatel94, @JuhiPal16, @showkat_09, @sanyog_negi

https://t.co/v8QuN8zCq3

[J Org Chem/Org Lett @JOC_OL]

In #OrgLett: @GharpureLab from @iitbombay demonstrates a simple tweak in gold(I) catalyst loading and reaction time results in divergent formation of isoxazolidine & isoxazoline via hydroamination/1,3-sulfonyl migration cascade. @sjgharpure, @JuhiPal16 https://t.co/cn1z0VycfR

[J Org Chem/Org Lett @JOC_OL]

Now in #OrgLett @GharpureLab reports MHAT 5-exo-trig and Baldwin-disfavoured 5-endo-trig radical cyclization for the synthesis of fused indoles and pyrroles, and accomplished total synthesis of bruceolline E/H https://t.co/6M0w0W155z @sjgharpure @RupaliSChavan @simrannarang89

[EurJOC @EurJOC]

Enantiospecific Total Synthesis of (-)-Hyacinthacine A1 and (+)-Hyacinthacine A1 and Their Homologues Using Nitrogen Substituted Donor-Acceptor Cyclopropane by @sjgharpure and @Rajpatel_91 @GharpureLab https://t.co/blyoaj6zNB

[Gharpure Lab @GharpureLab]

Happy to share our new approach for the enantiospecific total synthesis of both the isomer of Hyacinthacine A1 and their homologous !

[EurJOC @EurJOC]

Enantiospecific Total Synthesis of (-)-Hyacinthacine A1 and (+)-Hyacinthacine A1 and Their Homologues Using Nitrogen Substituted Donor-Acceptor Cyclopropane by @sjgharpure and @Rajpatel_91 @GharpureLab https://t.co/blyoaj6zNB

[Asian Chemical Editorial Society (ACES) @ACES_Journals]

Stereoselective Synthesis of Pyrrolo/Pyrido[2,1-a]isoindoles via Alkyne Iminium Ion #Cyclization of Vinylogous Carbamates. Santosh Gharpure et al. @iitbombay @GharpureLab @sjgharpure @sanyog_negi https://t.co/GUTZALgJX4

[J Org Chem/Org Lett @JOC_OL]

New in #OrgLett @GharpureLab demonstrates base-promoted synthesis of cyclic and spiro heterocyclic β-ketosulfones via hydroalkoxylation-initiated cascade of sulfone-tethered aryl alkynols https://t.co/I103ujuq4L

@sjgharpure, @DipakFartade, @Santoshknanda87, @Shipra_1997

[Gharpure Lab @GharpureLab]

@DharmendraSVish @JOC_OL @sjgharpure @Rajpatel_91 @guptakrish50 Thank you..

[Gharpure Lab @GharpureLab]

@nanda_laxmi Thank you..

[Gharpure Lab @GharpureLab]

Happy to share our new approach for pyrrolidine and piperidine natural products synthesis.

[J Org Chem/Org Lett @JOC_OL]

Now showing in #OrgLett, @GharpureLab discloses the stereoselective total synthesis of pyrrolidine and piperidine alkaloids via TMSOTf mediated ‘5/6-endo-dig’ reductive hydroamination of enynyl amines. See it here https://t.co/JzejfRY5Jl @sjgharpure, @Rajpatel_91, @guptakrish50,

[Chemical Communications @ChemCommun]

This year’s #RSCPoster is approaching fast! Everyone is welcome to take part, and registration is free. This is your chance to share your work with a global community of scientists 🧪🌍

Register now ➡️ https://t.co/cCqY1kilsd

[The Nobel Prize @NobelPrize]

BREAKING NEWS:
The Royal Swedish Academy of Sciences has decided to award the 2022 #NobelPrize in Chemistry to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless “for the development of click chemistry and bioorthogonal chemistry.”

[Gharpure Lab @GharpureLab]

Congratulations Sanyog !!! for your first publication. Wish many more to come...@sanyog_negi

[J Org Chem/Org Lett @JOC_OL]

Now playing in #JOC Kumari & Gharpure @sjgharpure @iitbombay demonstrate the protecting group dependent synthesis of densely substituted dihydropyrroles v/s pyrroles via 5-exo-trig cascade radical cyclization to alkynyl vinylogous carbamates. Here it is: https://t.co/EqtaGrQ0y8

[The Nobel Prize @NobelPrize]

BREAKING NEWS:
The 2021 #NobelPrize in Chemistry has been awarded to Benjamin List and David W.C. MacMillan “for the development of asymmetric organocatalysis.”

[Gharpure Lab @GharpureLab]

Heartiest congratulations to our farmer PhD student @DharmendraSVish for receiving SAILIFE-NOST Best Thesis award.

[Dharmendra S. Vishwakarma @DharmendraSVish]

I am happy to share that I have been selected for "SAILIFE-NOST Best Thesis award-2020" in Virtual JNOST confrence at IISC Banglore.
#BestThesisAward
#IITBombay
#GharpureLab

[Chemistry at Thieme @thiemechemistry]

Have you signed up for our SOS symposium on Nov 11? 🔝
Take the opportunity & join Gary Molander (@molandergroup), Alois Fürstner, Barry Trost, Janine Cossy, Mark Lautens (@MarkLautens) & Nuno Maulide (@MaulideLab) for this exceptional event!🎉
Read more: https://t.co/FahItB0rPI