Gout Study Group

The Gout Study Group is comprised of experts in the field of uric acid biology and basic and clinical science related to gout. Follow us for the latest on gout!

[Gout Study Group @GoutGroup]

A trial examined the safety and efficacy of pegloticase with methotrexate (MTX) vs placebo (PBO). Findings support MTX as an effective co-therapy to pegloticase. Read here: https://t.co/YjzybQ9KjS

[Gout Study Group @GoutGroup]

It was found that gout patients who experienced a cardiovascular event had significantly higher odds of a recent gout flare in the days before that event. Results suggest gout flares are associated with an increase in cardiovascular events. #gout https://t.co/OCt0ziyVGE

[Gout Study Group @GoutGroup]

A study examined the safety/efficacy of pegloticase combined with methotrexate in #gout patients. An increased proportion maintained therapeutic response at 6 months when treated with pegloticase and methotrexate compared to using pegloticase alone. https://t.co/DVCowKn1Zh

[Gout Study Group @GoutGroup]

A study performed a genome-wide transcriptome analysis on a gouty mouse model. Results showed transcriptional changes, namely elevated inflammation and broad activation of immune pathways in joint and nervous systems. https://t.co/SWH21jy9Be

[Gout Study Group @GoutGroup]

This study examined the frequency and predictors of flares over 2 years during a urate-lowering therapy treat-to-target strategy in #gout patients. Flares remained frequent during the first year but decreased in frequency during the second.

https://t.co/xMCDfcl2BD

[Gout Study Group @GoutGroup]

A study set out to develop and assess the usability of a web-based patient-tailored tool, I-Change Gout, to support urate-lowering therapy adherence in gout patients. Results provide initial support for the usability of this tool. https://t.co/XOb1auUvqu

[Gout Study Group @GoutGroup]

A study examined the relative efficacy and safety of allopurinol and febuxostat for the treatment of hyperuricemia. Both treatments reached serum urate goals in patients and allopurinol was found to be non-inferior to febuxostat in controlling #gout flares
https://t.co/KXEl3GQULM

[Gout Study Group @GoutGroup]

A Mendelian randomization analysis was performed to assess whether alcohol consumption affects the risk of developing hyperuricemia and gout. Results indicate that alcohol consumption doesn't have a causal effect on the development of hyperuricemia or gout
https://t.co/DsHBhU3Gvc

[Gout Study Group @GoutGroup]

A study assessed the accuracy and precision of 3MD with VMIs in the DECT assessment of MSU compared with a commercial 2MD and DT material decomposition methods. 3MD was found to be accurate and detects a lower concentration of MSU than either 2MD or DT. https://t.co/uJzTzYMmHj

[Gout Study Group @GoutGroup]

A study examined data between 2007-2008 and 2017-2018 to assess the trends in risk factor control and medication use to explore characteristics associated with risk factor control. Results showed a decreased blood pressure control trend. https://t.co/SinCeFhiBw #gout

[Gout Study Group @GoutGroup]

A study assessed the benefit of long term pegloticase use in #gout patients to lower serum urate. Results found that there were significant clinical benefits in patients achieving a urate-lowering effect in the first 6 months of treatment.
https://t.co/tSdTPuIyaz #medicine

[Gout Study Group @GoutGroup]

A study compared DECT examinations in 2013 and 2019 to assess the role of DECT in the clinical evaluation of #gout. Results indicate an evolving role for DECT in gout evaluation. Read about the results here: https://t.co/Fxbeav0Khr

[Gout Study Group @GoutGroup]

A study examined if following guideline-based healthy eating patterns was associated with risk of incident female gout. It was found that the women most adherent to these healthy diets had significantly lower risk of incident #gout.

https://t.co/e00FraKcdE

[Gout Study Group @GoutGroup]

A study examined the cost-effectiveness of various #gout treatments. Allopurinol and febuxostat were both found to be cost-effective compared to no therapy. Colchicine, naproxen, and prednisone had similar health economic implications.
https://t.co/86vUP1fyED

[Gout Study Group @GoutGroup]

This analysis examined whether single or repeat testing of serum urate more accurately predicts incident gout. It was found that repeat testing is not superior to a single measure for the prediction of incident #gout over time.
https://t.co/PkhgMpDikx

[Gout Study Group @GoutGroup]

A study examined the #gout incidence and association with behavioral factors within a large multiethnic adult population. Notable ethnic differences were observed in gout risk and associations with modifiable behavioral factors: https://t.co/HbVLJHMYpK

[Gout Study Group @GoutGroup]

This study set out to identify key genes and pathways related to #gout. It was found that pro-ADM expression was higher in the gout group, meaning it can be used as an inflammation-related biomarker for acute gout attacks.

https://t.co/hjkCJY414F

[Gout Study Group @GoutGroup]

A study assessed whether #gout is a risk factor for COVID-19 diagnosis and COVID-19 related death. Results found an increased risk of COVID-19 related death in those with gout with a greater burden in women than men.

https://t.co/4K91VEbAXm

[Gout Study Group @GoutGroup]

A rapid #gout detection method and kit were developed to facilitate the colorimetric diagnosis of gout.

https://t.co/7D5yU72x2v

[Gout Study Group @GoutGroup]

This study examined which attributes are most and least important to #gout patients when looking at flare burden over time.

https://t.co/YoKYPOnfme