@simocristea Tobias Hürter in "Too Big for a Single Mind" talks about a law of conservation of genius, where the brilliant theoretical physicists are often terrible at experimental physics, and vice versa. I think there is something along these lines in every field
Besides your 8 MB calculation is incorrect because it is based on the protein coding regions. It has been understood for a while that much of the step improvements in evolution happens in the regulatory non coding space. It is as if you are comparing two binaries by looking only at the .data 🤷♂️
To make the argument clearer, the folding is not entirely determined by the sequence. So not every stretch of a DNA sequence will fold the same way. It is governed by another orthogonal system of histones that you are not accounting for. This system keeps state that is inherited next to the actual DNA, and is the reason why 2 eggs can never merge to form a viable cell, they are not folded correctly
@fredsters_s If you had already done the work of doing self service, why not just keep the freemium but restrict it just enough so that it serves as a free demo environment but is unusable otherwise? That phone call is a barrier for most engineering types unless your company is well known
1/2 @mbiranek. I have never sought to *justify* Putin's indefensible invasion. I oppose all aggressive war on principle. Why can people not see the distinction between justifying an action, and explaining the conditions in which it became possible?
All of the plenary talks were amazing at Bridges this year! @mathgrrl gave the last one, and during the talk she gave everyone a 3D printed copy of this knot, which has the surprising property there does not exist a plane that is tangent to the knot in three places. So it rolls!
@nntaleb@LieraMarco Another factor: historically, the cost and inconvenience of traveling rate limited immigration, and probably selected for the type of ppl who could immigrate. Though I imagine exceptions exist (eg Germanic tribes to Rome?)
This video of a red-tailed hawk seemingly suspended in the air earned Bill Bryant the win for the Audubon Society 2021 Award in the video category [source: https://t.co/eaXlSEjHF0]. The hawk's head is perfectly still while its body stabilizes around it