Two decades of synthetic lethality in cancer with PARP inhibitors. Still one of the most fascinating mechanisms of actions for a targeted anticancer therapy. Reviewed by those that developed/unveiled it. https://t.co/6rDRtikQz8
Unfortunately I know friends who still suffer from Long-COVID while the current administration wants to forget and not measure the situation today or tomorrow.
Wonderful descriptive depiction. One take-home is that if you are getting infections despite vaccination, there is an evident, and high chance of long covid manifestation in bodily systems
I will make a thread on the charlatans who said long covid was less than 5% later
We should be prioritizing prevention of cancer instead of the major focus on detection and treatment. A new @CellCellPress perspective
https://t.co/Gkso3gGPOI
RxPONDER Cognitive substudy now out in @JAMAOnc
Chemo-ET: greater negative impact on pt-reported cognitive fnx vs ET alone in pre/post menopausal persistent over 36 mo
Further supports value of selecting pts who can avoid chemo
@KalinskyKevin@lynnhenrymd@irenekangmd
How a restricted diet (DR) improves the immune response to cancer and success of immunotherapy in the experimental model. T cell metabolic reprogramming @NatMetabolism
https://t.co/yMttGEmvLi
The "second brain" of the body—the gut (enteric) nervous system—can tamp down inflammation of the gut lining via release of a neuropeptide, a discovery that may help vs inflammatory bowel disease @NatImmunol
https://t.co/Q866pDnAdO
It's ridiculous this was even necessary.
The Annals of Internal Medicine has rejected HHS Secretary RFK Jr's demand to retract the Danish vaccine study of 1.2 million children, finding 'no evidence of scientific misconduct.' (1/2)
https://t.co/2Ljg7hEozJ"
BARDA invested in mRNA technology precisely because it could deliver safe, scalable vaccines in record time, a capability proven during COVID.
By dismantling that platform, we’re crippling our front-line defense, just ahead of unknown biological threats.
https://t.co/ymD0Y55gA0
Cambodia has confirmed its 15th human case of #H5N1 in 2025. That brings the year’s total to 15 cases and 7 deaths (CFR: 46.6%). Since 2005: 87 cases, 50 deaths (CFR: 57.5%).
#AvianInfluenza#Zoonoses#BirdFlu#Spillover
@tmprowell I am not often on this platform anymore but I am here reading this and wishing I could do more to mourn with you. I will continue to work toward fewer cancer deaths no matter what.
Today "a milestone in the evolution of personalized therapies for rare & ultra-rare inborn errors of metabolism"
—the 1st human to undergo custom genome editing
—outgrowth of decades of NIH funded research
https://t.co/HmJxYWDCV7
https://t.co/4DsNELnBut @NEJM
https://t.co/y7NMGPpXnE
Online now in our Computational Cancer Biology and Technology section "Characterization of an Enhance RNA Signature Reveals Treatment Strategies for Improving Immunotherapy Efficacy in Cancer" https://t.co/0XnedOD60C
By @lenghan_bioinfo et al.