Top Tweets for #ASOCHAT
Does neoadjuvant chemo before CRS/HIPEC help in metachronous CRPM? Across 199 patients, no diff in OS, RFS, PCI, or rate of CC — only higher periop morbidity. Findings similar to prelim results from CAIRO6 phase 3, argue for individualized selection @SocSurgOnc #ASOchat
July Issue: A Retrospective Examination of Neoadjuvant Chemotherapy for Metachronous Colorectal #PeritonealMetastases Prior to #CRSHIPEC @melanieongchin
https://t.co/R0HbCTPMcs
@SchultzKurt
@SyedAAhmad5
@SocSurgOnc
If you have retroperitoneal sarcoma, you may be interested in this #ASOchat among surgeons. #leiomyosarcoma #liposarcoma
@AnnSurgOncol @alegronchi STRASS2 (also known as EA7211 in the US) has accrued just over 160 patients internationally. We encourage surgeons to consider referring your pts for enrollment in this trial.#ASOchat
@kencardonaMD @DrPandalai @AMVillanoMD @JeffreyFarma @SyedAAhmad5 Dr. @kencardonaMD, I noticed that in the trial design collection of tumor tissue for central pathology review is mandatory. Any opportunities for correlative biomarkers / translational work here, or strictly for standardized histologic review? #ASOchat
@DrPandalai @AndrewFlemingMD @kencardonaMD @JeffreyFarma @SyedAAhmad5 Always tough balance between optimizing duration of follow up and getting answers soon enough. #RPS and other sarcomas are notorious for late recurrences like this. Yet another hurdle we face studying these #ASOchat @DrPandalai @AndrewFlemingMD
@DrPandalai @AndrewFlemingMD @JeffreyFarma @AMVillanoMD @SyedAAhmad5 Tom Delaney studied whether delivering higher radiation dose specifically to the “high-risk margin” — the region judged most likely to have microscopic residual tumor / positive margin — one might improve local control. Not universally standard. #ASOchat
@kencardonaMD @AnnSurgOncol @alegronchi @chandrajitraut @AMVillanoMD @JeffreyFarma Innovative design! Looking forward to following along! @Strexit2Horizon #ASOchat
@AndrewFlemingMD @AnnSurgOncol @alegronchi @chandrajitraut @AMVillanoMD @JeffreyFarma Yes. Internationally, all pts that meet STRASS2 enrollment criteria but do not enroll on trial are placed in registry arm of trial (STEXIT2). Real world date. #ASOchat
@AndrewFlemingMD @kencardonaMD @AnnSurgOncol @chandrajitraut Since I do love this topic and you asked @AndrewFlemingMD, a few more articles for light reading tomorrow #ASOchat
Experience from MDACC -https://t.co/lgsdORggBL
Work by @wbalrefaie and myself - https://t.co/nfQcFPtVCa
@DrPandalai @kencardonaMD @JeffreyFarma @AMVillanoMD @SyedAAhmad5 Great thought, @DrPandalai. Any idea if these patients will be followed that long? #ASOchat
Super important we all contribute the best we can to trials like these for rare diseases like #RPS! Thankful for having this open here in the US @kencardonaMD. Open here at @FoxChaseCancer #ASOchat
@AnnSurgOncol @alegronchi STRASS2 (also known as EA7211 in the US) has accrued just over 160 patients internationally. We encourage surgeons to consider referring your pts for enrollment in this trial.#ASOchat
Please keep the conversation going! and a huge thank you to @kencardonaMD as our invited expert and @DrPandalai @SyedAAhmad5 and @AMVillanoMD for helping to plan this event @SocSurgOnc @TARPSWG #sarcoma #ASOchat @CureSarcoma @AmCollSurgeons
@AnnSurgOncol and @SocSurgOnc want to thank all our participants for a great conversation. Looking for further comments and discussion regarding the always challenging management of RPS #sarcoma #ASOchat
@kencardonaMD What a wonderful way to close the discussion. More evidence that pre-op RT for WDLPS and G1-G2 DD LPS may improve abdominal RFS #ASOchat more to come and keep enrolling to STRASS 2 #sarcoma @SocSurgOnc @TARPSWG @SarcomaAlliance @CureSarcoma
Be sure to check out STRASS2 / EA7211, recruiting now! (NCT 04031677). #ASOchat
@AnnSurgOncol @alegronchi STRASS2 (also known as EA7211 in the US) has accrued just over 160 patients internationally. We encourage surgeons to consider referring your pts for enrollment in this trial.#ASOchat
@AnnSurgOncol @alegronchi @chandrajitraut In the study of rare cancers, studies such as this one are critical to continue to move the field forward and provide insight on histology-specfic mgmt. #ASOchat
@AndrewFlemingMD @kencardonaMD @AnnSurgOncol @chandrajitraut Of course! Great data that challenged the compartmental resection paradigm for a more histology-tailored approach #ASOchat
https://t.co/PopZcmHBFK
@AnnSurgOncol @alegronchi STRASS2 (also known as EA7211 in the US) has accrued just over 160 patients internationally. We encourage surgeons to consider referring your pts for enrollment in this trial.#ASOchat
9c. There was improved abdominal RFS in the pre-op RT cohort compared to surgery alone HR 0.61 95% CI (0.42-0.89) #ASOChat
9d. This improvement in abdominal RFS was even more pronounced for WD-LPS and G1/G2 DD-LPS patients (HR 0.63 95% CI 0.40-0.97) #ASOChat
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