Top Tweets for #Cellpress
🧬Could eating less protein help us age better?
A new #CellPress review highlights how protein and specific amino acid restriction may influence #longevity by reshaping nutrient-sensing pathways, mitochondrial function, and cellular senescence.
🔬A fascinating look at the biology behind healthy aging—and the potential of dietary interventions to modulate aging pathways.
#HealthyAging #AgingResearch #ProteinRestriction #Nutrition
🧬Research Spotlight | Is protein restriction the key to healthy aging?
A new #Cell Press Blue review synthesizes decades of research on how protein restriction (PR) and targeted amino acid restriction influence the biology of aging.
🔬Key insights:
🔹Protein restriction improves metabolic health and promotes longevity across multiple model organisms
🔹Restricting specific amino acids, particularly isoleucine, valine, and methionine, can recapitulate many benefits of dietary protein restriction
🔹These interventions regulate nutrient-sensing pathways including #mTORC1, #GCN2, #ATF4, and #FGF21, while reducing cellular senescence and improving mitochondrial function
🧬 Rather than simply extending lifespan, dietary protein restriction reshapes the biology of aging through:
🔹Improved metabolic health
🔹Nutrient-sensing pathway remodeling
🔹Reduced cellular senescence
🔹Enhanced mitochondrial function
🔹Epigenetic remodeling
🔹Healthy aging
#Aging #Longevity #ProteinRestriction #AminoAcids #Metabolism #DrugDiscovery #MedicinalChemistry
A #CellPress academic exchange event on July 14 at #HUST brought together over 30 young scholars and graduate students from mechanics, physics, and integrated circuits. #HUSTAcademic
Glad to have presented my work at the #CellPress Symposia, Multifaceted Mitochondria and to have spent 3 inspiring days exchanging ideas with fellow researchers in the field. Thanks to #ANRFIndia travel grant. Thanks to @NathSangeeta @MIRM_blr for the support! #X @PhDsofIndia
Online now: Computational protocol for hierarchical Bayesian modeling of perception and generalization in fear conditioning https://t.co/FzpbPY3v0F #protocol #starprotocols #cellpress
A new Cell study from Hashim M. Al‑Hashimi and colleagues shows how solution NMR can directly link RNA sequence to cellular activity by quantifying conformational ensembles.
Read more: https://t.co/X6GY07esip
#StructuralBiology #NMR #CellPress
Online now: High-resolution Hi-C profiling of human breast tissues using an optimized protocol for clinical samples https://t.co/YMMQuvY0oc #protocol #starprotocols #cellpress
Online now: Protocol for identification of protein citrullination by immunoprecipitation followed by mass spectrometry https://t.co/R1rOLiTRQH #protocol #starprotocols #cellpress
Online now: Protocol for generation of human gallbladder epithelia cells and their derived hepatocytes using a chemically defined approach https://t.co/NY9BooeKBR #protocol #starprotocols #cellpress
Online now: Protocol for modeling the repair of intestinal damage by co-culturing mesenchymal stromal/stem cells and intestinal organoids https://t.co/nT2CwZLRaP #protocol #starprotocols #cellpress
Online now: Protocol to investigate neurophysiological link between resting-state brain activity and clinical symptoms in methamphetamine use disorder https://t.co/9zvtxWCPZ4 #protocol #starprotocols #cellpress
Online now: Protocol for the preparation and analysis of patient-derived organotypic tumor spheroids https://t.co/6Is9aBWXzY #protocol #starprotocols #cellpress
Online now: Protocol to isolate broadly neutralizing monoclonal antibodies against SARS-CoV-2 from human B cells https://t.co/jv0m0BkvOK #protocol #starprotocols #cellpress
Online now: Protocol for nucleo-cytoplasmic fractionation of mammalian cells to study protein translocation via immunoblotting https://t.co/zKYcPjIk1f #protocol #starprotocols #cellpress
Online now: Protocol for quantifying hepatitis B virus transcript abundance and genomic segment distribution from single-cell RNA-seq https://t.co/aN65cS3nNN #protocol #starprotocols #cellpress
Online now: Protocol to study social transmission of stress in group-housed mice using restraint stress https://t.co/s1vHGBFScK #protocol #starprotocols #cellpress
Online now: Protocol for in vitro phagocytosis assay for primary mouse microglia and human embryonic stem cell-derived microglia https://t.co/rCEtE39bmR #protocol #starprotocols #cellpress
Online now: Protocol for RNA-seq library preparation from low-volume total RNA by RNA/cDNA hybrid tagmentation https://t.co/awgB2qxcrC #protocol #starprotocols #cellpress
Online now: Protocol for autofluorescence removal in microglia by photobleaching in free-floating immunofluorescent staining of mouse brain tissue https://t.co/fZ9XzrvoFq #protocol #starprotocols #cellpress
Online now: Protocol for in vivo assessment of glucose metabolism in mouse models https://t.co/q0JiZjc5ig #protocol #starprotocols #cellpress
Online now: Protocol for mitochondria lipid encapsulation using a dual-tube system for mitochondria transfer therapy https://t.co/ZCAYLHXbOk #protocol #starprotocols #cellpress
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