Top Tweets for #Drug_Interaction
#drug_interaction
🔴STATINS+ 🔴Strong CYP3A4 inhibitors
✅Inhibitors : protease inhibitors (including ritonavir), cobicistat,
clarithromycin, erythromycin, azole antifungals, cyclosporine,
grape fruit/grape fruit juice
📌Risk:
•↑ levels of CYP3A4 substrates: lovastatin, simvastatin, atorvastatin.
•↑ myopathy risk; if severe (with high CPK), can cause rhabdomyolysis with acute renal failure (ARF).
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