Top Tweets for #ENDIAstudy
Diet intake and physical activity in #pregnancy were similar for women with and without #type1diabetes, but overall suboptimal. #ENDIAstudy @BetaCellCRE @UniofAdelaide @RobsInstitute
Read here ➡️ https://t.co/fzD9R8L1wM
@AmDiabetesAssn @ADA_DiabetesPro @ADA_Pubs
ZnT8A detected in young children often progressed to multiple islet autoantibodies and were detected in multiple assay formats. ZnT8A detected by ELISA often remained single in older children and not detected in other assay formats #ENDIAstudy https://t.co/2cZPffMWJn
Positive results from #type1diabetes and #coeliacdisease #screening do not increase maternal perceived #stress some 1–2 years later. #ENDIAstudy @BetaCellCRE @UniofAdelaide @RobsInstitute https://t.co/t9gNOtl8ra
Altered vaginal microbiome composition in pregnancy with #T1D may be associated with pre-term birth and pre-eclampsia–G. vaginalis could be a target for future risk reduction strategies. #endiastudy #Microbiome #Pregnancy #PretermBirth #Preeclampsia https://t.co/0WJ5mOMV2k 🔓
@RobsInstitute past Director Prof Sarah Robertson, highlights the role of the institute to help Prof Couper bring the #endiastudy to further significant funding in 2015 from @JDRFaus and @HelmsleyTrust #rrisym
Wow! Changes in the maternal brain during pregnancy!
@BetaCellCRE #ENDIAstudy @UNSWObGyn_Paeds @UNSWBABS @UNSWMedicine @neuraustralia @MRC_microbiome @Amanda_Henry_AK @emadelomar
@JDRFaus @HelmsleyTrust @rlcmrf
So much more we should investigate in our pregnancy cohorts, that we hadn't appreciated/thought to look for and its possible association with virome, microbiome, developing fetus and child health implications!
Does the brain change during pregnancy? You bet it does. How about doing 26 MRI scans on a single person pre-conception to 2 years post-partum. WOW! Laura Pritschet and colleagues nailed it with their new paper in @NatureNeuro.
Key Points:
- The authors point out that pregnancy is a period of profound hormonal and physiological changes.
- The authors did something incredible by mapping neuroanatomical changes in an individual from preconception through two years postpartum.
- Boom! There were pronounced decreases in gray matter volume and cortical thickness.
- There were increases in white matter microstructural integrity, ventricle volume and cerebrospinal fluid.
- There were few regions untouched by the 'transition to motherhood.'
My take: This study shows us how a single brain in a single person can be a powerful resource when scanned serially over time. This method is hard to pull off, however what it has the potential to teach us about neuroscience is mind-blowing. Though this paper is only a single subject, the data provides a comprehensive map of the human brain across gestation. It will be interesting to add to the dataset, so we can understand changes across multiple persons and multiple conditions. The convergence of evidence is revealing that pregnancy as associated with dramatic neuroplasticity. How about a shout out to this 38-year-old woman who underwent 26 MRI scans along with blood draws from 3 weeks preconception through 2 years postpartum!
https://t.co/LEnPHzKCcl #pregnancy #brain @ndosenbach @andreashorn_ @EMiddlebrooksMD
A dietary pattern higher in fresh foods during #pregnancy was associated with a more than 60% reduction in risk of pre-eclampsia & premature birth in women with #type1diabetes. #ENDIAstudy @BetaCellCRE @UniofAdelaide @RobsInstitute https://t.co/v8JMMQpW2V 🔓
Buzzed to be a part (Aussie lead) of this cross-continent & cross-cohort (prospective #type1diabetes birth cohorts) collab between #ENDIAstudy @BetaCellCRE x #TEDDY
@NIH R01 @NIDDKgov
Kudos to PIs John Altin (Fellow Aussie) @TGenResearch & @jtladner @NAU for championing this!
Exciting work from our #ENDIAstudy collaborators.
Great news for women with #T1D in pregnancy who want to reduce risk of pre-eclampsia & preterm delivery. Eating more fresh food improves outcomes. Diet remains extremely important, even with new tech developments.
@LDC_tweets
Latest from the #ENDIAstudy: pregnant people with #T1D who consume a diet associated with relatively modest increases in fresh food reduce their risk of #preeclampsia by 63% and #prematurebirth by 65%. https://t.co/nebJVNMk2k @JDRFaus @HelmsleyTrust @BetaCellCRE @DiabetologiaJnl
Latest from the #ENDIAstudy: pregnant people with #T1D who consume a diet associated with relatively modest increases in fresh food reduce their risk of #preeclampsia by 63% and #prematurebirth by 65%. https://t.co/nebJVNMk2k @JDRFaus @HelmsleyTrust @BetaCellCRE @DiabetologiaJnl
Thank you to our funders for their continued support @HelmsleyTrust @DiabetesAus Australian Diabetes Society (ADS) @nhmrc @JDRFaus @JDRFResearch @EU_Commission @NIDDKgov @ispad_org @fidonlus and the village of study group members & participants of the #ENDIAstudy @BetaCellCRE !!!
Congratulations to the #ENDIAstudy team including our own @AveniHaynes1 @ProfLizDavis on the paper published in @ADA_Pubs 'Dysglycemia Is Detectable Using Continuous Glucose Monitoring in Very Young Children at Risk of Type 1 Diabetes'. Read it here👇 https://t.co/BLLDQlUVI3
#ENDIAstudy results in @ADA_Pubs reporting that #CGM is well tolerated in very young #isletautoantibody positive children showing measurable glycemic variability before requiring insulin and without #T1D symptoms https://t.co/LWWrLLlR6f @AveniHaynes1 @JDRFaus @HelmsleyTrust
The #ENDIAstudy cohort profile paper is out! We describe the demographics of 2435 parents of 1473 ENDIA children representing 1214 families across Australia united in finding the causes of #type1diabetes. Read more: https://t.co/iio7ARczTq @JDRFaus @HelmsleyTrust @BetaCellCRE
Similar studies & #t1d risk screening programs in Australia include our @Type1Screen, the #ENDIAstudy @BetaCellCRE and the general population screening pilot
Another exciting collaboration with the #ENDIAStudy
Randi K. Johnson, PhD, MPH, assistant professor in the @CUBiomedInfo, has received a $500,000 grant from @JDRFaus to investigate maternal pregnancy factors that impact the offspring’s risk of developing type 1 diabetes. Learn more about the study: https://t.co/qXP04obdJi
@maspenno @UniofAdelaide @RobsInstitute @ClaireMeek5 nicely said, Megan. Research knows no boundaries! Exciting times ahead for #ENDIAstudy
Some of our #ENDIAstudy participants may have never been to the UK, but their blood samples will soon be making the trip! The @UniofAdelaide @RobsInstitute are excited to collaborate with @ClaireMeek5 on this great project on #type1diabetes in #pregnancy 🤰💙
News | University of Leicester researcher joins global push to prevent type 1 diabetes
➡️ https://t.co/O7oSf0Carg
#CitizensOfChange | @ClaireMeek5 @LeicResearch @JDRFUK @LDC_tweets @HelmsleyTrust
Exciting new projects as #ENDIAstudy resources go global thanks to @JDRFaus and @HelmsleyTrust! The @UniofAdelaide @RobsInstitute team will be working closely with @CUBiomedInfo to investigate why #type1diabetes in pregnancy reduces a child's risk of developing #T1D 👩🔬🥼💙
Randi K. Johnson, PhD, MPH, assistant professor in the @CUBiomedInfo, has received a $500,000 grant from @JDRFaus to investigate maternal pregnancy factors that impact the offspring’s risk of developing type 1 diabetes. Learn more about the study: https://t.co/qXP04obdJi
@JDRFaus @AlboMP Even the Australian Prime Minister was interested in what the #ENDIAstudy team are planning with our new collaborators @DrSatvika @ClaireMeek5 @CUBiomedInfo @ufdiabetes and @tvatanen
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