Top Tweets for #FADRA
$CYCC has two candidates in its pipeline – #fadraciclib (#fadra) and #plogosertib (#plogo) – that are currently in Phase 1-2 for the treatment of different types of #cancer
#Fadra is our lead candidate, a next generation CDK2/9 inhibitor, that is currently being tested in patients with #solidtumors in our Phase 1/2 trial. Check our fadra snapshot or learn more at https://t.co/MsBMZruLYS
Check out a new article by Jordyn Sava at @TargetedOnc that perfectly summarizes our Phase 1/2 study of #fadra.
Read here: https://t.co/W8UdEMQCwt
#drugdiscovery #clinicaltrials #tumors
$CYCC has been investing in tablet formulation due to better patient convenience and increased compliance. They will be available for patients in the ongoing Phase 1 #fadra study.
More about our trials at https://t.co/eCCL40pRlh
Our Chief Executive Officer, Spiro Rombotis, joins @jaredstaylor of the @SliceofHC podcast to discuss the development of the company’s leading candidates targeting cell cycle inhibition for cancer.
#fadra #plogo #oncology #cellcycle
Listen here: https://t.co/kY1OAHC4K7
Choosing the optimal dose schedule is one of many parameters to increase the chance of success in Phase 2. Our #fadra has reached dose level 6A which is the final dose level outlined in the 065-101 protocol.
More at https://t.co/eCCL40pRlh
Would you like to learn more about our study design and the progress of oral #fadraciclib #fadra in patients with different types of solid tumors and lymphomas? Watch the video where Spiro Rombotis, CEO, presents our recent updates. $CYCC
https://t.co/qRMhl7YeNL
Would you like to learn more about our study design and the progress of oral #fadraciclib #fadra in patients with different types of solid tumors and lymphomas? Watch the video where Dr. Mark Kirschbaum, CMO, presents our recent updates. $CYCC
https://t.co/qRMhl7YeNL
2/ Ongoing Phase 1/2 clinical study of fadraciclib #fadra (dose level 6A) in patients with advanced solid tumors and lymphomas suggests achieving target engagement levels on continuous dosing. Data expected to be available in the middle of the year. $CYCC
Our lead candidate #fadraciclib (#fadra) is a dual inhibitor of both CDK2
and CDK9, enzymes involved in cell cycle regulation, whose inhibition induces
apoptosis resulting in death of cancer cells.
To learn more about our science, visit https://t.co/MsBMZruLYS
$CYCC
This year, the $CYCC team will continue to advance its pipeline for the treatment of #solidtumors and #lymphomas. With oral #fadra scheduled to enter Phase 2, we expect final data from the dose escalation stage and RP2D determination in 1H 2023.
More at https://t.co/MsBMZruLYS
2/ Four patients with cervical, endometrial, hepatocellular and ovarian cancer showed stable disease with target lesion reductions after the first 5 dose levels of oral #fadraciclib #fadra. $CYCC
https://t.co/9zrGQyFtd7
$CYCC ‘s lead candidate oral #fadra, a CDK2/9 inhibitor, shows broad activity in dose level 5 across multiple tumors and is now enrolling at final #doseescalation level 6a to determine RP2D in its Phase 1/2 study.
More on our updates at https://t.co/9zrGQyEVnz
#ListenIn to a new episode of @HopkinsBioPod where Spiro Rombotis, President and CEO of $CYCC, explains the #cellcycle targeting approach to treat cancers using their lead drug, oral #fadra.
Click to listen -> https://t.co/kZDXjqILvY
#podcast
Dose vs. schedule - What’s the right balance in a clinical trial? Listen to this episode of the #EmpoweredPatientPodcast as @karenjagoda speaks with $CYCC ‘s CEO, Spiro Rombotis, on clinical trials for #fadra, CDK2/9 inhibitor -> https://t.co/DyDdi84r6g #cancer
Listen to #podcast with @karenjagoda as she speaks with $CYCC ‘s CEO, Spiro Rombotis, on clinical trials for #fadra, CDK2/9 inhibitor, which forces cancer cells to undergo programmed cell death.
#ListenIn and #ReadOn at #EmpoweredPatientPodcast: https://t.co/DyDdi84YVO
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