Top Tweets for #KnowLPA
☝️PCSK9 Inhibitors & Lp(a): Beyond LDL-C Lowering
1️⃣ Evolocumab consistently reduces Lp(a) by ~20–25%, in addition to producing profound LDL-C reductions of approximately 60% across multiple clinical trials.
2️⃣ The magnitude of Lp(a) lowering correlates with LDL-C reduction, suggesting a shared biological pathway influenced by PCSK9 inhibition.
3️⃣ Patients achieving very low LDL-C (<40 mg/dL) experience greater Lp(a) reductions, supporting the concept that reduced LDL competition enhances Lp(a) clearance.
4️⃣ Experimental data indicate that Lp(a) can interact with the LDL receptor (LDLR), although with lower affinity than LDL. Increasing LDLR expression enhances Lp(a) uptake, while PCSK9 inhibition appears to facilitate this process.
👉These findings support the hypothesis that LDLR-mediated clearance contributes to Lp(a) reduction with PCSK9 inhibitors, providing a mechanistic explanation for a clinical observation that had long remained unclear.
🔗🔓 https://t.co/oyYKPYWcr1
@society_eas
@nationallipid

#NLA2026
Congratulations to @nationallipid on a superb annual meeting this past weekend!
The @FamilyHeartFdn team was honored to participate with a booth and two poster presentations on the state of LDL-C control.
🙏🏻 to everyone who visited with us!
#KnowFH
#KnowLpa

#KnowLpa
Great review from @CardiologyToday featuring @FamilyHeartFdn board member @hsbhatia
👇
Lp(a) and cardiovascular risk: What you should know https://t.co/vpxsx8Uyiy
🇺🇸 This #MemorialDay, we remember those who served and sacrificed. At the Family Heart Foundation, we honor their legacy by advancing a future where every heart is protected.
Together—we save lives through research, education, and advocacy.
#KnowFH #KnowLpa #KnowLDL

🙏🏻 to @payalkohlimd for volunteering her time for this important @FamilyHeartFdn webinar!
Please join us for this important conversation on the new 2026 Dyslipidemia Guidelines!👇
#KnowLDL
#KnowLpa
#LowestIsBest
Join us for a Family Heart Webinar: New Dyslipidemia Guidelines: Aligning Science and Care
The new U.S. dyslipidemia guidelines were released in March 2026, placing renewed emphasis on achievement of specific LDL-cholesterol goals, universal screening for Lp(a) in all adults, earlier detection of inherited cholesterol conditions such as familial hypercholesterolemia (FH), and more personalized prevention of atherosclerosis.
On May 19th, hear from Dr. Payal Kohli, FACC, and Family Heart Foundation Chief Innovation Officer, Hilly Paige, as they discuss what these guidelines mean for healthcare practitioners and the community.
Please join us for this interactive session to hear the latest on cardiovascular disease prevention, get your questions answered, and explore what’s ahead for high Lp(a), FH, and our community.
Register here: https://t.co/UIfVsCKfEy

🙏🏻 to @EliLillyandCo and @Amgen for providing unrestricted support towards our efforts to engage primary care clinicians at #IM2026!
#KnowLpa
#KnowLDL
#LowestIsBest
Three days at the @ACPIMPhysicians #IM2026 in San Francisco, and the engagement was incredible.
We achieved:
- A record-breaking 502 screenings on Day 1
- 850 screenings by Day 2
- An overflowing room for our Innovation Theater on lipoprotein(a) with Dr. Laurence Sperling.
Every conversation we have moves prevention forward. Thank you to those who engaged with us at ACP!
Learn more at https://t.co/gtziw4eKSR
#KnowFH #KnowLpa #KnowLDL

#KnowLpa
Great first panel at the @HealthyWomen “Do Your Part for Your Heart” event featuring @CNS_APRN from @TulaneMedicine and @KAWilemon from @FamilyHeartFdn. With genetic risk, the clock starts early, making early identification so critical!

Don’t overlook sex differences in CVH & explore our Lp(a)-related resources to learn more: https://t.co/D4AfvQRGqM #KnowLpa #LpaAwarenessDay @fhpatienteurope

We’re attending the @ACCinTouch Scientific Session & Expo this weekend in New Orleans.
Stop by to connect with the Family Heart team and learn more about resources for FH and high Lp(a). If you’re there, be sure to find us.
#KnowFH #KnowLpa #KnowLDL

#KnowLpa
Very interesting analysis! The @FamilyHeartFdn has launched a new educational campaign called Lp(a) AW(a)RE to address this!👇
Most Clinicians Not Prescribing Preventively for Elevated Lp(a) in Low-Risk Patients https://t.co/xedWINpplN
You can’t lower Lp(a) with #diet or #exercise.
But #lifestyle still matters.
🫀 Reduce overall #CV risk
🥗 Support metabolic #health
It’s about managing the whole risk profile
👉 https://t.co/TBvjeYnBW6
#KnowLpa #LpaAwarenessDay #Cardiology @society_eas
Encourage your patients with elevated Lp(a) levels to maintain a healthy lifestyle, and make sure you also learn more about lipoprotein(a) through our educational resources: https://t.co/D4AfvQRGqM #KnowLpa #LpaAwarenessDay @fhpatienteurope

Lp(a) testing isn’t just clinically important.
It’s economically smart.
📊 Cost-effective in primary prevention (40–69y)
✔️ Better risk prediction
✔️ Better outcomes
✔️ Better use of resources
Why aren’t we implementing it?
👉 https://t.co/TBvjeYnBW6
#KnowLpa @society_eas
The International Study on the cost-effectiveness of Lp(a) testing shows that using Lp(a) to reclassify cardiovascular disease (CVD) risk in the primary prevention population aged 40–69 years is a highly cost-effective way to prevent CVD.
Implementing Lp(a) testing is not only strongly justified from a clinical perspective, but is also likely to deliver a financial return on investment when considered from a societal perspective.
These results support the immediate implementation of Lp(a) testing in primary prevention populations in high-income countries.
Learn more about this study and other Lp(a)-related initiatives here: https://t.co/JpII7Aq5a8 #KnowLpa #LpaAwarenessDay @fhpatienteurope

Thank you, @Hasselbeck, for sharing your story and helping us highlight why understanding your risk for cardiovascular disease matters for individuals and families.
Learn more about Cholesterol Connect and get your screening kit: https://t.co/Jp95IOMj6k 💗
#KnowLpa #KnowLDL
Encourage your patients with elevated Lp(a) levels to maintain a healthy lifestyle, and make sure you also learn more about lipoprotein(a) through our educational resources: https://t.co/D4AfvQRGqM #KnowLpa #LpaAwarenessDay @fhpatienteurope

Learn about the unique role of Lp(a) as a genetic determinant for #ASCVD risk & the importance of testing for Lp(a) levels to better understand your patients’ cardiovascular health w/ ACC's online course. ⬇️
More: https://t.co/OY9j8lZRfI
#LpaAwarenessDay #KnowLpa #ACCEd

Thank you to everyone who made this #LpaAwarenessDay so impactful. Every post, share, and conversation helped raise awareness about Lp(a) and reach more families with lifesaving information. Learn more and get free at-home screening at https://t.co/mFh4ZEuTTm. #KnowLpa
Dr. @ijeomaheartdoc of @EmoryMedicine and Family Heart Foundation Ambassador Chuck Lane help raise awareness about lipoprotein(a) as part of our Lp(a) Awareness Media Tour.
https://t.co/roPLoeYU2e
#KnowLpa #LpaAwarenessDay
March 24 is Lipoprotein(a) Awareness Day. Elevated Lp(a) is an inherited, often under-recognized cardiovascular risk factor. Today we recognize the importance of awareness and education to #KnowLpa. Learn more from the @FamilyHeartFdn: https://t.co/z034Ysfloh

Check out this free CME opportunity on #LpaAwarenessDay! Knowledge is power.👊 #KnowLpa
🔗https://t.co/G0plBM2Pfe
Don’t miss this FREE CME opportunity!
Elevated Lp(a) is a key risk enhancer for ASCVD. This 2-part on-demand series with Drs. Erin Michos & Pamela Morris breaks down what you need to know about Lp(a), LDL-C, and management strategies.
Start learning now: https://t.co/T3BHHf7g9p
@medliveofficial @ASPCardio

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