Top Tweets for #PRIOn
It was great to host Dr. DeFranco from @ColoradoStateU (Telling Lab)
Joe delivered a fantastic seminar on #prion strain evolution and gene-targeted mice that sparked lively discussions and ideas for future collaborations. Bonus: we officially welcome Joe to #KriosHugger community
@Franca_ole I doubt $RHHBY, $ALPMY, or $LLY would move seriously on $SGMO 's STAC-BBB platform without seeing credible human validation.
The fastest way to achieve that is through #Prion Disease: ST-506
TgVole(I109)1x 🐁 for #Prion Bioassays: Baseline Definition of Spontaneous Neuropathology to Ensure Accurate Interpretation. 🧠🔬
Inés Xancó @CReSA_r en colaboración con @CICbioGUNE
Trial readiness for preventive gene therapy in hereditary #prion disease: willingness, preferences, and decision-making among confirmed carriers and individuals at genetic risk. 🧠🧬🥼
Hasier Eraña @CICbioGUNE
In vitro evaluation of Jamaican fruit bat as a potential vector of #prion diseases. 🦇🔬🧠
Carlos M. Díaz-Domínguez @CICbioGUNE @ColoStateNews (Colorado State University; CIC bioGUNE).
Cristina Sampedro‑Torres‑Quevedo @CICbioGUNE
Rapid generation of #prion disease models using AAV‑delivered PrP variants in knockout mice
$SGMO says tox studies for #Prion are now complete and negotiations are proceeding for the CTA in Great Britian
Any food that contains thiaminases will make you worse. You need thiamine to survive.. Plant proteins kill… more thiamine = stronger plant defence. Less thiamine neurological issues.
#vaccineinjury #thiamine #prion #moderna #pfizer
$SGMO Prion ST-506 gene therapy poster. I believe this is new. >95% PRNP prion repression https://t.co/tE1r9inVed
$XBI #prion #FDA @RFKJr_Official @FDA @US_FDA
$SGMO #PRION
Creutzfeldt–Jakob disease is an Alzheimer’s disease-related dementia
evidence that, like Creutzfeldt–Jakob disease, Alzheimer’s disease and Alzheimer’s disease-related dementias may be #transmissible under rare circumstances.
https://t.co/TxQJy8c6qh
Nice paper from colleagues emphasising prion-like mechanisms in dementia and inclusion of CJD in funding mechanisms for dementia disorders. Surprising resistance to prion-like mechanisms in dementia communities which imo often stems from poor understanding https://t.co/Yt9YCTHsnz
Malgré des biais méthodologiques grossiers en faveur des vaccins, un risque accru de 23% d'hospitalisation pour cancer après injection ARNm (+80% après correction) https://t.co/ztsuQZw60Y via @GibertiePatrice
@PhiBoostGlow @CoyoteSanctuary @HouseLyndseyRN @Ryanmor54929339 @dryostradamus @brucep13 @JCPEREZCODEX @MeasslainteIRL I followed McCairn's call, so in order: #KevinMcCairn Live Stream 15/10/2025 / #NeuroWarfare: Fixing Bayonets Against #PRION Invasion...
@GothamGirl_1 @Corona_N_Lyme @sandymacrae23 @SangamoTx @JohnMarkels I agree in part. That said, $RHHBY and $LLY likely have strong interest in $SGMO ’s STAC-BBB #capsid.
But its real value begins only once it is validated in humans (#prion disease).
That creates some shared interest and should make some form of financing possible.
#TWEETORIAL
Have you ever heard of the terms 'Agrypnia Excitata', 'Oneiric Stupor' or 'Fatal Familial Insomnia'? If you are a medical history nerd like me, read this 🧵 to learn more!
#NeuroX #Neurology #SleepMedicine #Parasomnia #Prion #Epilepsy #Dementia #CJD
@Franca_ole It seems highly unlikely that @genentech would file an #IND for $SGMO ’s STAC-BBB #capsid before any human data exist. The first clinical testing will likely be in #prion disease, probably not before the end of this year.
$RHHBY @SangamoTx
📢#Specialissue: From #Prion #Molecular #Mechanisms to Targeted Therapeutics: Informing the Broader #Proteinopathy #Paradigm
⏰Deadline: 31 August 2026
🎓Guest Editors: Dr. Patricia Aguilar-Calvo
📖Find out more at https://t.co/o5ycr7LHX9 @MDPIBiologySubj
$SGMO
One of the more recent developments is a patent application for the treatment of #prion diseases, published as WO2025/194009. It describes zinc finger proteins that are designed to specifically repress the PRNP gene. Since prion proteins play a central role in diseases such as Creutzfeldt-Jakob disease, this technology could open up long-term therapeutic approaches for neurodegenerative diseases that have been difficult to treat until now. This application is currently still in the international PCT process, but will typically be converted into national patents later on including in China, Japan and South Korea.
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