Top Tweets for #Painscience
Choose an evidence-informed Refresher Course in pain research, clinical care, policy or education before Bangkok: https://t.co/v0BWrXzaZJ #WC2026 #PainScience
Choose an evidence-informed Refresher Course in pain research, clinical care, policy or education before Bangkok: https://t.co/D95U2WgCCT #WC2026 #PainScience
Choose an evidence-informed Refresher Course in pain research, clinical care, policy or education before Bangkok: https://t.co/aik3OA1ab1 #WC2026 #PainScience
14 days to Bangkok. Past attendees: What is one piece of advice or one must-do you would share with a first-time attendee? Explore #WC2026: https://t.co/FzhPMwmWWw #PainScience
14 days to Bangkok. Past attendees: What is one piece of advice or one must-do you would share with a first-time attendee? Explore #WC2026: https://t.co/7IkfDuSm4L #PainScience
Build your #IASP2026 schedule before you arrive in Bangkok. Use the official app to save sessions, set reminders, review poster abstracts, navigate BITEC and receive program updates: https://t.co/ynVtOHrRyz #PainScience
#Chronicpain is still often misunderstood when patients’ standard tests show “normal” results.
In his latest post, Tonix CEO @SethLederman, M.D. discusses why listening to patients and integrating the latest #painscience is key to better care.
Read more: https://t.co/zoIXpvzVAl
Many patients with #chronicpain are told that nothing is wrong when their tests appear normal.
In my latest post, I explain why this gap persists and how the latest #painscience research can explain symptoms that imaging cannot capture.
We need to listen more closely to patients.
Read more: https://t.co/1r7SFojsZE
Three weeks to Bangkok. What are you most looking forward to at #IASP2026: the science, practical learning, posters, networking or something else? Share it in the comments. #PainScience
🟢 OPEN ACCESS - https://t.co/1EA8onI5FI - Physiotherapy waiting times can be a window of opportunity to provide short, digital pain science education. This can support patients whilst they wait but did not enhance usual physiotherapy care #Physiotherapy #PainScience #PatientEducation #DigitalHealth
🧬 Los biomarcadores podrían transformar la forma de comprender y evaluar el dolor, pero... ¿hasta dónde llega realmente su utilidad?
Conoce la evidencia actual en este webinar de EFIC
📅 22 de septiembre | 12:30 h (CET)
🔗 https://t.co/EGjS5Ngesf
#PainScience #DolorCrónico #Investigación #Biomarcadores
Pain science advances when global perspectives come together. More than 5,000 pain professionals will meet in Bangkok for #WC2026, with plenary speakers from around the world. Meet the faculty: https://t.co/yoGZibDgNx #PainScience
Pain science advances when global perspectives come together. More than 5,000 pain professionals will meet in Bangkok for #WC2026, with plenary speakers from around the world, including @link_physio. https://t.co/oJxsL22qyz #PainScience
Pain science advances when global perspectives come together. More than 5,000 pain professionals will meet in Bangkok for #WC2026, with plenary speakers from around the world, including @link_physio. https://t.co/nJeGgknRg7 #PainScience
Pain science advances when global perspectives come together. More than 5,000 pain professionals will meet in Bangkok for #WC2026, with plenary speakers from around the world, including @link_physio. https://t.co/yoGZibDgNx #PainScience
🧠⚡ 𝗡𝗢 𝗡𝗢𝗖𝗜𝗖𝗘𝗣𝗧𝗢𝗥𝗦 - 𝗪𝗛𝗬 𝗕𝗟𝗢𝗖𝗞 𝗧𝗛𝗘 𝗡𝗘𝗥𝗩𝗘?
#RegionalAnaesthesia #RegionalAnesthesia #PainScience #Nociception #Nociceptors #PainPathways #NerveBlocks #Transduction #InflammatoryPain #NeuropathicPain #MechanismBasedAnalgesia #AnesthesiaEducation #PainMedicine #RAEducation #MedEd
#GrayZonesInRA #GrayAreasInRA
𝗚𝗥𝗔𝗬 𝗭𝗢𝗡𝗘𝗦 𝗜𝗡 𝗥𝗔:
🔬 𝗔. 𝗡𝗢𝗖𝗜𝗖𝗘𝗣𝗧𝗢𝗥𝗦 𝗚𝗘𝗡𝗘𝗥𝗔𝗧𝗘 𝗧𝗛𝗘 𝗦𝗜𝗚𝗡𝗔𝗟
▫️ Nociceptors are specialized sensory nerve endings.
▫️ Their membranes contain receptors and ion channels.
▫️ They detect heat, pressure, acidity, ATP & tissue injury.
▫️ Inflammatory mediators activate or sensitize them.
▫️ A local generator potential develops.
▫️ A weak stimulus may remain below threshold.
▫️ A strong or prolonged stimulus reaches threshold.
▫️ An action potential is then generated.
▫️ This conversion is called TRANSDUCTION.
⚠️ An action potential is a nociceptive signal, not pain itself.
🔥 𝗕. 𝗡𝗘𝗥𝗩𝗘𝗦 𝗧𝗥𝗔𝗡𝗦𝗠𝗜𝗧 𝗧𝗛𝗘 𝗦𝗜𝗚𝗡𝗔𝗟
▫️ Nociceptors generate the signal.
▫️ Peripheral nerves transmit it.
▫️ The spinal cord processes it.
▫️ The brain interprets it as pain.
🌊 Inflammation is the WATERFALL.
▫️ Nociceptors are the TURBINES.
▫️ Nerves are the transmission CABLES.
▫️ No turbine means no electricity.
▫️ No functioning nociceptor means no inflammatory signal from that tissue.
✂️ 𝗖. 𝗪𝗛𝗔𝗧 𝗔𝗙𝗧𝗘𝗥 𝗧𝗜𝗦𝗦𝗨𝗘 𝗘𝗫𝗖𝗜𝗦𝗜𝗢𝗡?
▫️ Excision removes the tissue & its nociceptors.
▫️ The removed tissue cannot generate inflammatory signals.
▫️ Its nerve cannot transmit signals from tissue that no longer exists.
▫️ Blocking that nerve only because it previously supplied the tissue may add little benefit.
▫️ However, the wound still contains nociceptors.
▫️ Skin, fascia, muscle & periosteum may remain painful.
▫️ The same nerve may supply these structures.
▫️ A proximal block may therefore still provide analgesia.
⚡ 𝗗. 𝗪𝗛𝗘𝗡 𝗜𝗦 𝗧𝗛𝗘 𝗡𝗘𝗥𝗩𝗘 𝗕𝗟𝗢𝗖𝗞 𝗨𝗦𝗘𝗙𝗨𝗟?
▫️ When remaining painful tissues share that nerve.
▫️ When the surgical wound lies in its territory.
▫️ When nerve injury causes ectopic discharges.
▫️ When regeneration or neuroma creates neuropathic pain.
▫️ A proximal block may interrupt these signals.
⚠️ No painful territory + no nerve injury + no ectopic activity = little reason to block.
💊 Neuropathic pain requires a different strategy.
▫️ Anti-inflammatory drugs target nociceptor activation.
▫️ Neuropathic agents target abnormal neural excitability.
🎯 𝗞𝗘𝗬 𝗧𝗔𝗞𝗘𝗔𝗪𝗔𝗬𝗦
▫️ Nociceptors generate the signal.
▫️ Nerves normally transmit the signal.
▫️ Excision removes that tissue’s inflammatory generator.
▫️ The nerve block is not automatically useful.
▫️ Block the current pain pathway, not the historical innervation.
🔥 No nociceptor input and no ectopic discharge - little value in blocking the nerve.
⚡ Remaining nociceptive input or an injured nerve - the block may still help.
🧠 Do not ask only, “Which nerve supplied the structure?”
🎯 Ask, “What is generating the pain signal now?”
Can your expectations actually change how your brain experiences pain?
On this week's episode of Bendy Bodies, we discuss research showing that expectations can influence how the brain processes pain.
#ChronicPain #PainScience #Neuroscience #HypermobileEDS #BendyBodiesPodcast
Pain can persist when the brain detects a mismatch between body signals and expectations.
This doesn't mean the pain is imaginary: It means the nervous system may still be in protection mode, even after the original threat has changed.
#PainScience #Neuroscience #BrainHealth
Ziru’s project at KITE Research Institute is to develop and test an AI-enabled, clinician-supervised Brain Rewiring Application for people with #ChronicPain
Join me in welcoming Dr. Ziru Wang to Canada!🇨🇦
#CanadaLeads #UHN #AI #PainScience #Neuroscience #BrainScience
Pain doesn’t stay in one place
💬 Have you ever treated one area and noticed relief somewhere else?
#BendyBodies #ChronicPain #Hypermobility #PainScience #Substack
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