Top Tweets for #PoweredbyPacBio
The COVID-19 pandemic highlighted the urgent need for widespread genomic surveillance. This preprint paper presents a program that addresses this need.
#PacBio sequencing is the backbone of the program.
See more: https://t.co/CErYKWZ33D
#PoweredByPacBio
March's #PoweredByPacBio blog is out! Check out March's studies, showcasing discoveries from fusion detection to the genetics of taste, all thanks to #PacBio HiFi sequencing.
Check it out.๐ https://t.co/5ssIUl1Fag
Dive into the world of rare structural variants with #PacBio HiFi long-read whole genome sequencing.
This study integrates trait-relevant polygenic scores to understand complex rare diseases. Learn more about the innovative approach: https://t.co/hO3ym3UXBi
#PoweredByPacBio
New research, new breakthroughs! A new study reveals 16.7% of samples analyzed with #PacBio technology identified new genetic insights. Explore how long-read sequencing advances precision medicine research: https://t.co/qABbIKUwEI
#PoweredByPacBio #Revio
Here, the authors describe CosMIC as a hybrid approach for large-scale, high-resolution microbial profiling of novel niches. This powerful tool for profiling microbial diversity detected over 40,000 novel small subunits.
https://t.co/k7mrH33roe
#PoweredByPacBio
We will let this paper on #AAV #GeneTherapy, speak for itself.
โLong HiFi reads using SMRT sequencing enabled high-throughput analysis for identification of novel AAV clones recovered from animal tissues.โ
https://t.co/HFraPYoDeR
#PoweredByPacBio
Can your short-read NGS system detect a 91.5kb deletion in the alpha-globin cluster?
HiFi sequencing can.
Want to know more? See this publication for all the details: https://t.co/ruxugJUs7R
#PoweredByPacBio #HiFisequencing
An exciting new publication shows the first-ever isoform-resolved transcriptome of early human development!
This paper identified 110k+ unannotated isoforms and demonstrated the complexity of the human embryo transcriptome.
#PoweredByPacBio #PacBio https://t.co/xaG7P1ArQO
An exciting new publication shows the first-ever isoform-resolved transcriptome of early human development!
This paper identified 110k+ unannotated isoforms and demonstrated the complexity of the human embryo transcriptome.
https://t.co/mCxx3Y1cz4
#PoweredByPacBio #PacBio
While challenging to profile, tandem repeats are a critical part of the genome.
Using, in part, HiFi sequencing, this preprint developed a tandem repeat catalog and a tandem repeat benchmark for future genomics standards.
https://t.co/dppIS21Hk3
#PoweredByPacBio #PacBio
When faced with the challenge of detecting ultrarare mutations, these researchers turned to #PacBio HiFi sequencing. Why? Game-changing sensitivity. Read the full paper here: https://t.co/FYu3U0WZGD
#PoweredByPacBio #ASHG23 #ASHG2023
Here, the authors used #HiFisequencing to obtain 30 anammox genomes. (2/2)
https://t.co/s6xPy4XiRL
#PoweredByPacBio
The genome of the world's first domesticated crop, einkorn wheat, became a little less grainy.
In this powerful paper, the authors used #HiFisequencing to uncover the population structure and evolutionary history of einkorn.
https://t.co/vHleYvGaFx
#PoweredByPacBio
When faced with the challenge of detecting ultrarare mutations, these researchers turned to #HiFisequencing.
Using PacBio technology, they detected off-target effects of DNA base editors that do not create double-strand DNA breaks.
https://t.co/FYu3U0WZGD
#PoweredByPacBio
In this powerful preprint, researchers used HiFi whole genome sequencing to further characterize a variant associated with progressive neurodegeneration.
Explore the results here: https://t.co/b8uU0uGc6i
#PoweredByPacBio
Congenital adrenal hyperplasia (CAH) is related to mutations in the CYP21A2 gene, which is difficult to differentiate from its pseudogene CYP21A1P.
Researchers used #PacBio sequencing to distinguish between these two genes correctly.
https://t.co/BwrFPr6zIx
#PoweredByPacBio
In this study, the authors evaluated the most widely used conventional and AI-based variant calling tools.
The results demonstrate the impressive accuracy and quality of #HiFisequencing.
Read more: https://t.co/nWsph9gbM0
#PoweredByPacBio #PacBio
Cancer research breakthroughs are #PoweredByPacBio!
Learn how Suenaga et al. used full-length RNA sequencing (Iso-Seq method) to provide new insights into cancer evolution.
https://t.co/XJWKWtpBpB
#PacBio tech provides effective genetic analysis with the Iso-Seq method!
Li et al. report: "Compared with traditional methods, this LRS method can achieve a precise, comprehensive and intuitive result."
https://t.co/BwrFPr6zIx
#PoweredByPacBio #HiFisequencing
#PacBio assemblies helped shake the tree of life close to its base!
The authors report new chromosome-scale genomes supporting ctenophores as sisters to other animalsโproviding a new framework for our understanding of #evolution.
https://t.co/91kRdvqWgN
#PoweredByPacBio
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