Top Tweets for #cul4b

almost 4 years ago

Check out our preprint on #CRL4 #paralogs! The unstructured N-terminus of #Cul4B, which we as #Biochemists/#structuralbiologists have long ignored, is regulating the CRL4 function, and preferentially recruits a subset of DCAFs! #ubiquitin #phosphorylation #cytoskeleton #cellcycle

almost 4 years ago

Protein paralogs perform specific functions? Check our new preprint https://t.co/DM2ElKrbZ4 from lab headed by talented @StierAnna, Samuel @weaam_i CUL4B plays #mitosis-specific functions using #phosphorylated & #disordered N-ter Extension. #Ubiquitination #IDPs @ETH @ETH_DBIOL

almost 4 years ago

Did you know #CUL4B is not just #CUL4A? @StierAnna, Samuel, @weaam_i from @PeterLab8 found CUL4B N-term is disordered, phosphorylated and recruits specific #DCAFs relevant for #mitosis and #braindev. Congrats!🥂 @ETH @ETH_DBIOL #E3ligase #ubiquitin #PTMs #XLID #LIS1 #WDR1

almost 4 years ago

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